Brain's food pleasure linked to insulin resistance in obesity study

NCT ID NCT02241603

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 37 obese adults to understand why the brain's pleasure response to food is weaker in obesity. Researchers tested if insulin resistance in the brain causes this reduced response and if weight loss can improve it. The goal is to learn why weight loss is hard and find new ways to treat obesity.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St. Louis VA Medical Center John Cochran Division, St. Louis, MO

    St Louis, Missouri, 63106, United States

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