Experimental drug targets psoriasis and heart risks in one shot

NCT ID NCT04776629

First seen May 19, 2026 · Last updated May 21, 2026 · Updated 1 time

Summary

This study tested a drug called orticumab in 77 adults with moderate-to-severe psoriasis who also had heart disease risk factors like obesity and high cholesterol. The goal was to see if the drug could safely improve skin symptoms and reduce inflammation. Participants received either orticumab or a placebo, and researchers measured changes in psoriasis severity over 15 weeks.

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Contacts and locations

Locations

  • Blue Coast Research Center

    Vista, California, 92083, United States

  • CCT Research - Springville Dermatology

    Springville, Utah, 84663, United States

  • CCT- Research at the center for Dermatology and Plastic Surgery

    Scottsdale, Arizona, 85260, United States

  • Center for Clinical Studies, LTD.LLP

    Webster, Texas, 77598, United States

  • Dawes Fretzin Clinical Research Group, LLC

    Indianapolis, Indiana, 46250, United States

  • Derm Institute & Skin Care Ctr., Inc.

    Santa Monica, California, 90404, United States

  • Excel Clinical Research

    Las Vegas, Nevada, 89109, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • Las Vegas Clinical Trials

    Las Vegas, Nevada, 89030, United States

  • Orange County Research Center

    Tustin, California, 92780, United States

  • SMS Clinical Research

    Mesquite, Texas, 75149, United States

  • Texas Dermatology and Laser Specialists

    San Antonio, Texas, 78218, United States

  • Vital Prospects Clinical Research Institute, PC

    Tulsa, Oklahoma, 85260, United States

Conditions

Explore the condition pages connected to this study.