Which exercise burns fat better: upper or lower body?

NCT ID NCT07658261

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at how upper body versus lower body combined strength and endurance training affects two key proteins in overweight and obese men: myostatin, which regulates muscle growth, and hormone-sensitive lipase, which helps break down fat. Thirty-six men were split into three groups: upper body training, lower body training, or no exercise. The goal is to see if focusing on different body parts changes how these proteins respond, which could inform better exercise recommendations.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
combined resistance and aerobic training
What this could lead to
If successful, this could help tailor exercise programs to better target muscle growth and fat metabolism in overweight individuals.
What could go wrong
This is a small, early-stage study with only 36 participants, so results may not apply to everyone. It measures biological markers, not long-term health outcomes.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Sports and Health Sciences of the University of Tehran

    Tehran, Tehran Province, Iran

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