Which exercise burns fat better: upper or lower body?
NCT ID NCT07658261
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how upper body versus lower body combined strength and endurance training affects two key proteins in overweight and obese men: myostatin, which regulates muscle growth, and hormone-sensitive lipase, which helps break down fat. Thirty-six men were split into three groups: upper body training, lower body training, or no exercise. The goal is to see if focusing on different body parts changes how these proteins respond, which could inform better exercise recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
combined resistance and aerobic training
What this could lead to
If successful, this could help tailor exercise programs to better target muscle growth and fat metabolism in overweight individuals.
What could go wrong
This is a small, early-stage study with only 36 participants, so results may not apply to everyone. It measures biological markers, not long-term health outcomes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Sports and Health Sciences of the University of Tehran
Tehran, Tehran Province, Iran