Exercise plus taurine may fight hidden muscle fat in older women

NCT ID NCT07730255

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether 16 weeks of supervised exercise, with or without daily taurine supplements, can reduce fat stored inside the muscles of women aged 60–75 with obesity. Researchers will use MRI scans, muscle biopsies, and blood tests to measure changes in muscle composition, physical function, and gene activity. The goal is to see if this combination can improve muscle health and mobility without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
taurine dietary supplement and concurrent exercise training
What this could lead to
If it works, this could point toward a non-drug strategy to reduce harmful fat inside muscles and improve mobility in older women with obesity.
What could go wrong
This is a small, early-stage trial with only 44 participants. The results may not apply to men or people with different health profiles, and taurine may cause digestive side effects.

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Escola de Educação Física e Esporte de Ribeirão Preto, Ribeirão Preto, São Paulo.

    Ribeirão Preto, São Paulo, 14040-900, Brazil

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