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Three-Day fast reshapes fat cells and boosts fat burning, study hints

NCT ID NCT07692646

Recruiting now Knowledge-focused Sponsor: University of Copenhagen Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study investigates what happens inside the body after an 84-hour fast. Researchers will measure peak fat oxidation (how well the body burns fat during exercise), mitochondrial coupling (energy efficiency in cells), and changes in the extracellular matrix (the scaffold around fat cells). The trial includes 40 healthy adults—half with normal weight and half with obesity—to see if fasting affects these processes differently depending on body weight and sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
84-hour fasting
What this could lead to
If successful, this could reveal how fasting changes the body's ability to burn fat and remodel tissue, pointing toward new approaches for weight management.
What could go wrong
This is a small, early-stage study with only 40 participants. Results may not apply to older adults or people with medical conditions. Fasting for 84 hours can be difficult and may cause side effects like dizziness or fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fasting Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FASTING OBESITY (BMI>30) SEX DIFFERENCE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Biomedical Sciences

    RECRUITING

    Copenhagen, 2200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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