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Nighttime CO2 buildup: a hidden clue in sleep apnea?

NCT ID NCT07809061

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers at a French sleep center are studying adults with obesity who are referred for a sleep study because of suspected obstructive sleep apnea. The team measures how much carbon dioxide builds up in the blood overnight using a skin sensor, then compares that cumulative exposure to the severity of sleep apnea and to sleep quality. Participants also fill out a short questionnaire about how groggy they feel right after waking. The goal is to see whether this carbon dioxide measure adds useful information beyond standard sleep study readings.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the link holds, doctors could gain a new way to measure how much nighttime carbon dioxide exposure matters in obesity-related sleep breathing problems, possibly refining who needs closer attention.
What could go wrong
This is an observational study, so it can show associations but cannot prove cause and effect. The findings may not apply beyond adults with obesity referred for a sleep study, and the carbon dioxide measurement itself can be affected by sensor placement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Nov 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Body mass index (BMI) ≥30 kg/m². * Referred to the Sleep Medicine Center for routine diagnostic polysomnography because of suspected obstructive sleep apnea. * Affiliated with a French health insurance scheme. * Received information about the study and did not object to the use of their data. * Able to understand the study information and complete study questionnaires. Exclusion Criteria: * Legal incapacity or inability to provide non-opposition to participation. * Previous treatment with continuous positive airway pressure (CPAP) or non-invasive ventilation. * Participation in another interventional clinical study that could interfere with the present study.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder obesity-hypoventilation syndrome obstructive sleep apnea syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity (bmi>30) Obesity hypoventilation syndrome (OHS) Obstructive sleep apnea Sleep hypoventilation

How to take part

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  1. The places running it

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  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Croix-Rousse Hospital, Hospices Civils de Lyon

    Lyon, 69004, France

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