Cure My Disease

Don't miss your cure!

 Log in / Sign up

Does concentrating change your breathing? study probes Brain-Breath link in opioid users

NCT ID NCT07829055

Knowledge-focused Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Researchers at UC San Diego want to know whether doing a mental task changes breathing differently in people who take opioid pain medicine every day, people with obstructive sleep apnea, and healthy adults. The study compares three groups of 40 adults in total. Each participant visits the sleep lab once to answer questions and have sensors placed on the skin and scalp. While resting and while doing short computer or paper tasks, their breathing, brain waves, and oxygen levels are recorded. No medicine or treatment is given.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study finds that opioids or sleep apnea disrupt the link between brain activity and breathing, it could shape future research into safer pain treatment and breathing monitoring.
What could go wrong
This is a small observational study of 40 people at a single visit, so it cannot prove cause and effect. Results may not apply to other patients or doses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who have been seen at UC San Diego

Ages

45 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria All participants * Able to provide informed consent * Able to communicate in English, see/hear task stimuli (with usual corrective devices), follow multistep instructions, and complete a brief cognitive-task practice example Opioid group * Daily prescribed opioid use, under medical supervision, for chronic non-cancer pain, for ≥3 months * Prescribed dose ≥20 MME/day (no upper limit) * Stable dose for ≥2 weeks OSA group \- Diagnosed OSA with AHI ≥15 events/hour (documented on a prior clinical sleep study) Healthy control group * No history of chronic prescribed opioid use * No known history/diagnosis of OSA * If a prior sleep study exists, AHI must be \<10 events/hour within the past 3 years Exclusion criteria * Prisoners * Pregnancy * BMI \<20 or \>35 * Unable/unwilling to give informed consent or comply with study procedures * Significant comorbidities of other organ systems (e.g., chronic kidney disease, CHF/active cardiac symptoms, cirrhosis, severe lung disease) * Diseases affecting respiratory muscles or breathing control (neuromuscular, neurodegenerative, congenital) * Psychiatric disease other than controlled mood disorders

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Obstructive sleep apnea are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obstructive sleep apnea Opiod use disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of California San Diego

    San Diego, California, 92037, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.