Can science unlock the secrets of the naturally lean?

NCT ID NCT03981432

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study looks at what makes some women naturally lean without dieting or eating disorders. Researchers will compare eating habits, physical activity, body composition, and appetite responses in three groups: constitutionally lean women, normal-weight women, and women with anorexia nervosa. Participants will take part in lab sessions to measure how exercise and meals affect their appetite and food intake. The goal is to better understand the biological and behavioral profile of natural leanness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Behavioral interventions: rest with fixed meal and rest with ad libitum meal
What this could lead to
If successful, this could help explain why some people stay naturally lean without eating disorders, potentially guiding healthier approaches to weight management.
What could go wrong
The study is small and observational in nature, so findings may not apply broadly. It does not test a treatment, so it won't directly change clinical care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chu Clermont Ferrand

    Clermont-Ferrand, 63003, France

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