Can a memory drug break the grip of Anorexia's rigid habits?
NCT ID NCT06518941
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial tests whether donepezil, a medication used for memory, can help adults with anorexia nervosa weaken the strong habits that drive restrictive eating. Ten participants will receive the drug for up to 8 weeks while staying in an inpatient unit, with weekly check-ins to monitor side effects. Researchers will also measure changes in habit strength and food preferences to see if the approach is worth studying further.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- donepezil
- What this could lead to
- If donepezil proves tolerable and shows promise, it could offer a new medication to help people with anorexia nervosa break rigid eating habits and improve recovery.
- What could go wrong
- This is a very small, early-stage trial focused on feasibility and safety, not effectiveness. Donepezil may cause side effects, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
New York State Psychiatric Institute
New York, New York, 10032, United States
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