Kids' obesity may change how acid reflux drugs work
NCT ID NCT04248335
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how obesity affects the way children's bodies process common acid reflux medications like lansoprazole and pantoprazole. Researchers gave a single dose of these drugs to 76 children aged 6-21, both with and without obesity, and measured how long the drugs stayed in their blood. The goal was to understand if obesity changes drug clearance and dosing needs, which could lead to safer, more effective use in kids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lansoprazole, Pantoprazole, Midazolam
- What this could lead to
- If successful, this could help doctors prescribe more accurate doses of acid reflux drugs for children with obesity.
- What could go wrong
- This is a small, completed study focused on measuring drug levels, not testing a new treatment. Results may not apply to all children or lead to immediate changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Mercy Kansas City
Kansas City, Missouri, 64108, United States
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