Kids' obesity may change how acid reflux drugs work
NCT ID NCT04248335
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how obesity affects the way children's bodies process common acid reflux medications like lansoprazole and pantoprazole. Researchers gave a single dose of these drugs to 76 children aged 6-21, both with and without obesity, and measured how long the drugs stayed in their blood. The goal was to understand if obesity changes drug clearance and dosing needs, which could lead to safer, more effective use in kids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lansoprazole, Pantoprazole, Midazolam
What this could lead to
If successful, this could help doctors prescribe more accurate doses of acid reflux drugs for children with obesity.
What could go wrong
This is a small, completed study focused on measuring drug levels, not testing a new treatment. Results may not apply to all children or lead to immediate changes in care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Mercy Kansas City
Kansas City, Missouri, 64108, United States