Children's Mercy Hospital Kansas City

This study looks at two ways of taking progesterone for teens with Turner syndrome who are on hormone replacement therapy. One group takes progesterone for 12 days each month, the other takes it every day. Researchers will track bleeding patterns and how the teens feel, to see wh…

This study tests whether a portable, low-field MRI machine can detect brain injuries in children who are on ECMO (a heart-lung bypass machine). The MRI is brought to the bedside, avoiding the need to move critically ill children. Researchers will scan children at several time poi…

This study is testing a new, portable MRI machine that uses a very low magnetic field on children who already need a brain scan. The goal is to see if this low-field MRI can produce images as good as standard MRI, CT, or ultrasound. Up to 250 children from birth to 22 years old w…

This study looks at whether the measles, mumps, and rubella (MMR) vaccine is safe and works well in children aged 1 to 17 who have had a heart transplant. About 60 children will receive the standard MMR vaccine and be monitored for side effects and immune response. The goal is to…

This study adapts a group therapy program called Regulating Together for children aged 8-12 with autism and intellectual disability who struggle with emotions like irritability and aggression. The therapy uses relaxation, mindfulness, and parent training to help kids regulate the…

This study tests whether a home-based virtual reality (VR) neurofeedback program is practical and helpful for adolescents aged 10-16 with migraine. Participants use a wearable EEG headband that reads brain activity and guides the VR experience during short sessions three times a …

This study tests a group program to help teens (ages 13-17.5) with Prader-Willi Syndrome and their families learn practical ways to handle irritability, meltdowns, and anxiety. Ten participants will attend weekly 90-minute sessions. The goal is to see if the program improves emot…

This study tests whether live, group exercise sessions delivered via video chat can improve fitness in teens (ages 12-19) with certain types of congenital heart disease. 74 participants will either join the remote exercise program or receive standard exercise handouts. The main g…

This study is testing a device called ViBandz, which uses small vibrating motors strapped to the body to provide vibration therapy. Researchers want to see if it is easy and comfortable for children with neurological conditions to use at home. The study will involve 30 children a…

This study tests whether two 90-minute sessions of Focused Acceptance and Commitment Therapy (FACT) can reduce stress, anxiety, and depression in parents of children aged 2-6 with pediatric feeding disorder. About 80 parents will be randomly assigned to FACT or a nutrition educat…

This study tests a survey called Spotlight AQ that teens and young adults with type 1 diabetes fill out before their clinic visit. The survey asks about their therapy, feelings, social life, and diabetes knowledge. Doctors then use the results to guide the visit. The goal is to s…

This study tests a new pillow-like device that helps babies with tracheostomies (breathing tubes) lie on their stomachs for tummy time. Researchers want to see if the device fits well, is comfortable, and allows the baby to breathe safely. Parents and healthcare providers will sh…

This study looks at how liver fat changes the way the body processes rosuvastatin, a common cholesterol drug, in children aged 8 to 21. Researchers will give a single dose to 50 kids with high cholesterol and measure drug levels and response. The goal is to understand if fatty li…

This study is testing how the drug trihexyphenidyl is processed in the bodies of 40 children aged 5-17 with dystonic cerebral palsy. Researchers want to see if a child's genetic makeup changes how the drug works, which could help create personalized dosing plans. Participants wil…

This study is testing a new, low-field MRI scanner on 500 children to see if it can produce clear brain images without the need for sedation. The goal is to compare this portable scanner to standard MRI, CT, or ultrasound. If successful, it could make brain imaging safer and more…

This study looks at how liver congestion and scarring affect the way the body processes two common drugs, sildenafil and pravastatin, in people with Fontan circulation. Researchers will give a single dose of each drug to 15 participants aged 8 and older and measure drug levels in…

This study tests whether functional MRI (fMRI) brain scans can detect changes caused by a single dose of naltrexone in adolescents aged 13-21 with eating disorders involving binge eating or purging. Participants receive both naltrexone and a placebo in random order, two weeks apa…