Fatty liver may alter statin effects in kids, study warns

NCT ID NCT04903223

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how liver fat changes the way the body processes rosuvastatin, a common cholesterol drug, in children aged 8 to 21. Researchers will give a single dose to 50 kids with high cholesterol and measure drug levels and response. The goal is to understand if fatty liver increases the risk of side effects or makes the drug less effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rosuvastatin 10mg

What this could lead to

If successful, this could help doctors personalize statin doses for children with fatty liver, reducing risk of side effects or treatment failure.

What could go wrong

This is a small, early-phase study (50 participants) focused on understanding drug behavior, not testing a new treatment. Results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia lysosomal lipid storage disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact