Which progesterone schedule works best for turner syndrome teens?

NCT ID NCT06834594

Recruiting now Disease control Sponsor: Children's Mercy Hospital Kansas City Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at two ways of taking progesterone for teens with Turner syndrome who are on hormone replacement therapy. One group takes progesterone for 12 days each month, the other takes it every day. Researchers will track bleeding patterns and how the teens feel, to see which schedule works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Micronized progesterone (oral capsules)
What this could lead to: If it works, this could point toward a better hormone replacement schedule for teens with Turner syndrome, improving bleeding control and daily comfort.
What could go wrong: This is a small, non-randomized study at one hospital, so results may not apply to everyone. It compares two existing treatments, not a new drug, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

primary ovarian failure Turner syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY OVARIAN INSUFFICIENCY (POI) TURNER SYNDROME

Contacts and locations

Locations

Children's Mercy Hospital
RECRUITING

Kansas City, Missouri, 64108, United States

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