TURNER SYNDROME

This study tests three doses of vosoritide in 30 children with Noonan syndrome who are still growing but didn't get enough height from growth hormone treatment. The main goal is to see if vosoritide can speed up their growth over 6 months. Researchers will also check for side eff…

This study tests if a once-weekly growth hormone injection works as well as a daily one in children with short stature due to Turner syndrome, SHOX deficiency, being small at birth, or unknown causes. About 186 children will receive either the weekly or daily treatment for up to …

This study looks at how taking progesterone continuously versus in a cycle affects menstrual bleeding in teenagers with Turner Syndrome who are on hormone replacement therapy. Researchers will track bleeding patterns and any related distress. The goal is to find which approach wo…

This study looks at why some people with conditions like Turner Syndrome or galactosemia have trouble getting pregnant, and whether freezing their ovarian tissue can help them have a child in the future. Up to 200 participants aged 2 to 35 will have a small piece of ovarian tissu…

This study tracks 93 women with Turner Syndrome who wanted to become parents. Researchers will count how many succeeded through natural pregnancy, egg donation, or adoption. The goal is to understand the real-world success rate of having children for these women.

This study aims to understand why many people with Turner syndrome experience hearing loss. Researchers will analyze blood samples and perform hearing, balance, and imaging tests on 150 adults with Turner syndrome and healthy controls. The goal is to find specific genetic and epi…

This study follows 400 people aged 12 and older who have or are at risk for noncirrhotic portal hypertension (NCPH), a liver condition that raises blood pressure in the liver without scarring. Researchers will use regular check-ups, imaging, and tests to see how the disease chang…