Can freezing ovarian tissue help people with turner syndrome or early menopause have kids?

NCT ID NCT04948658

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether freezing ovarian tissue can help preserve fertility in people aged 2-21 with conditions like Turner syndrome, galactosemia, or premature ovarian insufficiency. Participants may have surgery to remove and freeze a gonad, with a small piece used for research. The goal is to understand why these conditions cause infertility and if frozen tissue can be used later for childbearing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gonadal tissue freezing (cryopreservation)

What this could lead to

If successful, this could offer a way for people with certain conditions to preserve their fertility and potentially have biological children in the future.

What could go wrong

This is an early-stage observational study, not a treatment trial. The frozen tissue may not lead to successful pregnancy, and storage costs after one year are not covered.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disorder of sexual differentiation galactosemia ovarian dysfunction primary ovarian failure Turner syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••