Can freezing ovarian tissue help people with turner syndrome or early menopause have kids?
NCT ID NCT04948658
First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 5 times
Summary
This study looks at whether freezing ovarian tissue can help preserve fertility in people aged 2-21 with conditions like Turner syndrome, galactosemia, or premature ovarian insufficiency. Participants may have surgery to remove and freeze a gonad, with a small piece used for research. The goal is to understand why these conditions cause infertility and if frozen tissue can be used later for childbearing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gonadal tissue freezing (cryopreservation)
- What this could lead to
- If successful, this could offer a way for people with certain conditions to preserve their fertility and potentially have biological children in the future.
- What could go wrong
- This is an early-stage observational study, not a treatment trial. The frozen tissue may not lead to successful pregnancy, and storage costs after one year are not covered.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New weekly shot could help girls with turner syndrome grow taller
- Major study launches to unravel mysteries of early menopause
- DNA hunt for why some women face early menopause
- Stem cell shot into ovaries aims to tame perimenopause symptoms