Which iron pill works best? small study tests natural vs. standard supplements

NCT ID NCT07563686

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how well healthy pre-menopausal women with low iron stores absorb iron from two different supplements: Spatone (a natural iron-rich water) and ferrous sulphate (a standard iron pill). Fourteen women took three different doses (5, 10, and 15 mg) of each supplement in a random order. Researchers measured iron absorption by tracking a special stable isotope in the blood. The goal was to see which supplement and dose provides the best iron uptake, which could help guide dietary recommendations for iron deficiency.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Spatone (natural iron-rich water) and ferrous sulphate (standard iron supplement)

What this could lead to

If it works, this could help identify which iron supplement is better absorbed, potentially improving dietary advice for women with low iron.

What could go wrong

This is a small, early-stage study with only 14 participants, so results may not apply to everyone. It measures absorption in a lab setting, not real-world effectiveness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

iron deficiency anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • King's College London

    London, Greater London, SE1 9NH, United Kingdom