Dietary guidelines put to the test: does weight loss boost heart benefits?
NCT ID NCT04293224
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether following a Mediterranean-style diet based on U.S. dietary guidelines improves heart health more when combined with weight loss. Researchers will provide all meals for 70 adults with obesity or excess body fat for eight weeks. Participants will be split into groups: some will eat enough to maintain weight, while others will eat less to lose weight. The goal is to see if weight loss adds extra benefits for blood sugar, cholesterol, and blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mediterranean diet pattern
What this could lead to
If successful, this could show that combining a healthy diet with weight loss is better for heart health than diet alone.
What could go wrong
This is a small, early-stage study (70 people) that only looks at short-term changes. Results may not apply to everyone, and the diet is provided, which may not reflect real-world eating habits.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
UC Davis, Western Human Nutrition Research Center
RECRUITINGDavis, California, 95616, United States