Anxiety disorder

This study tested a treatment called CPT-SMART that combines PTSD therapy, smoking cessation counseling, medication, and financial incentives to help veterans quit smoking. 120 veteran smokers with PTSD were randomly assigned to either the full program or a control group. The goa…

This study tests a program called Project YES+ for youth aged 15-21 living with HIV in Zambia. The program combines peer mentoring with mental health support to reduce stigma, violence, and depression. Researchers will enroll 400 participants to see if the program is feasible and…

This study tests whether a combination of a special omega-3 supplement (LIPINOVA®) and a home-based exercise and education program can improve quality of life for people with lingering post-COVID symptoms. About 146 adults aged 18–70 who have had symptoms for more than 12 weeks w…

This trial tests whether a structured family support program helps relatives of critically ill patients in intensive care units (ICUs). The program includes a specialist nurse who supports families from admission through discharge and follow-up, plus better communication between …

This study tests a small ear device that gently stimulates nerves to see if it helps people with both PTSD and opioid use disorder stay on buprenorphine therapy. Twenty participants will use either the active device or a placebo for 12 weeks. Researchers will check if they keep t…

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tests whether a computer-assisted tool helps mental health providers in rural VA clinics deliver cognitive behavioral therapy (CBT) more effectively for depression and anxiety. About 34 therapists and 167 veterans will take part. Therapists are randomly assigned to use…

This small study tested whether transcranial magnetic stimulation (TMS) can lower blood pressure and ease PTSD symptoms in women aged 18-44 who have both conditions. Four participants received 30 TMS sessions over 6 weeks. Researchers measured changes in 24-hour blood pressure an…

This study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to s…

This completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…

This Phase 3 trial tested a once-daily extended-release capsule called centanafadine in 315 adults with both ADHD and anxiety (generalized or social anxiety). For 8 weeks, participants received either the drug or a placebo. The study measured changes in ADHD symptoms using a clin…

This study looked at 6 people with schizophrenia who were already taking a combination of two long-acting injectable medications: Abilify Maintena and Rexulti. Researchers tracked their symptoms and side effects over 6 months to see how well the combo worked in everyday life. The…

This study tested a blended collaborative care model that uses telemedicine to integrate mental health treatment into primary care at smaller VA clinics serving rural veterans. Researchers enrolled 318 veterans who screened positive for depression, alcohol use disorder, or PTSD. …

This study tested whether a 3-year physical activity program could help prevent colon cancer from coming back in 889 patients who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. Participants were randomly assigned to either the exercise program plus…

This study tested whether giving people with alcohol dependence a one-month course of diazepam (40 mg per day) after detoxification could reduce the chance of relapsing into drinking within the next three months. The standard detoxification treatment is usually about one week. Th…

This study tested a program called Positive Minds-Strong Bodies Enhanced (PMSB-E) in 427 older adults from racial, ethnic, and linguistic minority groups who had depression, anxiety, and some mobility issues. The program combined mental health support with physical exercises to h…

This study tested whether N-acetylcysteine (NAC), a widely available supplement, could help people with both alcohol use disorder and PTSD. 182 adults took either NAC or a placebo daily for 12 weeks, along with weekly therapy. Researchers measured changes in drinking habits, crav…

This study tested two ways to help primary care doctors prescribe opioids more safely for patients with chronic pain, depression, or anxiety. One approach used an electronic tool that reminded doctors about risk checks and guidelines. The other added a team of a pharmacist, a soc…

This study tested a collaborative care model for people with opioid use disorder and depression, anxiety, or PTSD. 567 adults received medication (buprenorphine-naloxone or naltrexone) along with therapy and support from a primary care team. The goal was to reduce opioid use and …

This study tested a 12-month telephone-based nurse care program for 805 adults with depression and signs of opioid use disorder. Participants were randomly assigned to receive nurse support or usual care. The goal was to see if the program could improve treatment for opioid use a…

This early-stage study tested whether a brief therapy program plus a mobile app could help pregnant and postpartum women stay on their buprenorphine medication for opioid use disorder. Fifteen pregnant women took part, attending therapy sessions and using the app for up to 9 mont…

This study tested whether a speech analysis platform called AcceXible can accurately screen for depression and anxiety in university students. Over 900 students aged 16-25 provided voice samples through open-ended speaking tasks. The platform analyzed acoustic and linguistic feat…

This study tested a smartphone app that analyzes speech to screen for depression and anxiety in 785 university students aged 16-25. Participants completed speaking tasks, and the app's accuracy was compared to standard mental health questionnaires. The goal is to provide a quick,…

This study tested whether personalized, intensive nursing follow-up (by phone, home visits, or hospital consultations) after a suicide attempt could prevent another attempt or crisis in people with mood disorders. 380 participants were followed for one year. The goal was to see i…

This study tested whether prazosin, a drug normally used for high blood pressure, could prevent post-traumatic stress disorder (PTSD) in people who recently experienced a traumatic event like an accident or assault. Researchers gave the drug to 15 adults who showed signs of acute…

This study tested an online mentoring program for transgender and gender minority youth aged 14-18. The program paired each teen with an adult transgender mentor for seven 90-minute group sessions focused on building social and emotional skills. The goal was to prevent problems l…

This study follows up on 217 children who took part in a cognitive behavioral therapy program for anxiety and depression 5 years earlier. Researchers want to see if the program helped prevent these conditions from developing or worsening over time. The children, now teenagers, wi…

This study tested an online program called PROCARE-I+ designed to prevent anxiety and depression in teenagers who are at high risk. Thirty adolescents with early symptoms took part in the program, which included extra modules tailored to their needs. Results showed improvements i…

This study tested an online psychological program designed to prevent depression in people with atrial fibrillation (AF), a common heart rhythm problem. The program combined phone or video sessions with online modules and exercises over 4-12 weeks. The trial included 28 adults wi…

This study tested whether a single dose of hydrocortisone, given within 6 hours of a traumatic event, could prevent PTSD. 201 trauma survivors from two hospitals received either hydrocortisone or a placebo. Researchers tracked their mental health for 28 weeks to see if the drug r…

This trial investigates whether a structured educational program led by nurses can reduce anxiety and improve outcomes for adults undergoing their first heart surgery. Participants are randomly assigned to receive either the nurse-led program or usual care. The program covers pre…

This study tested whether a 3-month home exercise program on an elliptical machine and 3 months of bright light therapy could improve movement, balance, and mood in adults with traumatic brain injury. Thirty-four participants (including healthy volunteers) were enrolled. The goal…

This trial explores whether a group-based psychomotor therapy—using breathing, relaxation, and body awareness exercises—can be a practical and acceptable way to help young adults (ages 18-35) with anxiety. The study focuses on whether people will join and stick with the program, …

This study tests whether a 6-week mindfulness program (MBSR) can reduce PTSD symptoms and improve quality of life in people who have been in a road traffic accident. About 110 adults aged 18-60 with PTSD will be randomly assigned to either MBSR or standard care. Researchers will …

This study tests whether a brief, telehealth-delivered therapy called Written Exposure Therapy (WET) can help autistic adults who have experienced trauma. Participants complete five weekly writing sessions and wear a Fitbit to track sleep, activity, and heart rate. The goal is to…

This study tests whether writing about imagined future scenarios (worst-case, best-case, or neutral) can reduce social anxiety symptoms. 270 adults with elevated social anxiety will complete three online writing sessions over three weeks. Researchers will measure changes in anxie…

This study tests whether watching an augmented reality (AR) educational video on a tablet can lower anxiety in people about to undergo cardiac catheterization, a common heart procedure. Participants in the experimental group view the AR video in addition to receiving standard pap…

This study tested whether using a stress ball during a routine fetal checkup (non-stress test) helps pregnant women feel less anxious and more comfortable. 70 pregnant women participated. The goal was to see if this simple, drug-free tool can improve the testing experience for mo…

This study tests whether a headset that delivers tiny electrical pulses to nerves behind the ear can reduce anxiety in teens aged 12-17 with Generalized Anxiety Disorder. Sixty participants will use either the active device or a sham (fake) device for 30 minutes a day, 5 days a w…

This study tests whether watching short telenovela-style videos can reduce anxiety and boost confidence in African-American and Hispanic family caregivers of hospice patients. 62 caregivers will either watch the videos during telehealth visits or receive usual hospice care. The g…

This study tests whether a mindfulness app called Headspace can help low-income parents reduce stress, anxiety, and depression. Participants use the app on their own schedule for guided meditations. Researchers measure changes in stress and mood over time to see if the app provid…

This study tested whether using a virtual reality headset showing calming scenery for 20-30 minutes could lower anxiety in parents whose children were in the hospital. 485 parents participated, and their anxiety levels were measured and compared to standard care without any tech-…

This pilot study tests whether a short, evidence-based therapy called Written Exposure Therapy (WET) can help reduce PTSD symptoms in adults who are in residential treatment for substance use disorders. Participants complete five guided writing sessions about their trauma. The st…

This trial tests whether a brief online group therapy called EMDR Flash can help adults who survived the 2023 Kahramanmaraş earthquakes in Türkiye. Participants receive two 60-90 minute group sessions via Zoom and are compared to a waitlist group. The study measures changes in PT…

This study tested a 5-month early time-restricted eating plan (eating only between 7 AM and 3 PM) in 100 highly trained young male judo athletes. Researchers measured changes in body composition, muscle damage markers, and psychological factors like anxiety and self-confidence. T…

This pilot study tested a six-session culturally adapted cognitive behavioral therapy (Ca-CBT) for depression and anxiety in 50 people living with HIV in Pakistan. The therapy was delivered by trained HIV health workers and included culturally relevant stories and materials. The …

This study tested a counseling program called Youth Friendship Bench SA for young women aged 18-25 in South Africa who had symptoms of depression, anxiety, or stress. The program included individual and group counseling sessions, plus optional text reminders. The goal was to see …

This study tests whether placing ice inside the rectum before a prostate biopsy can lower pain, anxiety, stress hormone levels, and complications like bleeding. About 84 men having their first prostate biopsy will either receive standard care or ice application. The goal is to se…

This study tested whether adding dog-assisted therapy to usual care helps teens aged 12-18 with mental health issues like anxiety, depression, and emotional dysregulation. 70 teens in a day hospital were randomly assigned to either get dog therapy plus usual care or usual care al…

This study tested whether special light glasses could improve sleep, concentration, and mood in university students. 39 students with sleep problems wore the glasses for three weeks. The goal was to see if different light intensities made a difference. If successful, light therap…

This pilot study tested whether a non-invasive device that uses magnetic pulses to stimulate the brain (rTMS) could safely help cancer survivors with depression and anxiety. Twenty-four adults who had been treated for any type of cancer and still had major depression received eit…

This trial investigates whether a double-reading animated film, watched by both children and their parents before surgery, can reduce anxiety in children aged 3 to 7. The film uses avatars to walk the child through their hospital journey, from room to operating room. Researchers …

This study tested whether squeezing a stress ball or listening to music during coronary angiography (a heart imaging procedure) can lower pain and anxiety. 180 patients were randomly assigned to use a stress ball, listen to music, or receive standard care. Researchers measured an…

This study tested whether watching calming nature videos through virtual reality glasses or doing progressive muscle relaxation exercises could reduce anxiety in high-risk pregnant women during a non-stress test (NST). 126 women were randomly assigned to one of three groups: VR, …

This study tests whether a mobile app providing education based on the Life Model can help reduce anxiety and improve daily living activities in people who have had their thyroid gland removed for benign disease. About 68 participants will either receive standard discharge instru…

This study tested whether watching an animated educational video before a nail biopsy could reduce anxiety, improve understanding, and boost satisfaction. Thirty adults scheduled for a nail biopsy were shown the video. Researchers measured their anxiety, health literacy, and sati…

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study tested whether online counseling from a nurse, starting 24 hours before a colonoscopy, could help patients feel less pain and anxiety and be more comfortable. Sixty adults were split into two groups: one got standard care, the other got extra nurse support via face-to-…

This study tested whether repeating positive affirmations during a routine pregnancy test (Non-Stress Test) can lower pain, anxiety, fear, and stress. 90 pregnant women participated, with some using affirmations and others receiving standard care. The goal is to see if this simpl…

This study tested whether daily gummies containing L-theanine and lion's mane mushroom extract could reduce stress, anxiety, and improve sleep in university students. 67 students aged 18-25 took either the gummies or no supplement for 8 weeks. The goal was to see if this natural …

This study looked at whether touch-massage can reduce anxiety in people with blood disorders (like leukemia or lymphoma) who are hospitalized in a sterile, isolated room. Sixty-two patients received three massage sessions, and researchers measured their anxiety levels before and …

This study tested whether monthly 45-minute psychological interviews over 6 months could reduce post-traumatic stress symptoms in cancer patients affected by the COVID-19 pandemic. It included 29 adults with solid tumors who had moderate to high PTSD symptoms. The goal was to see…

This completed study tested two psychological techniques—imagery rescripting and imaginal exposure—in 6 adults with obsessive-compulsive disorder (OCD) who experience distressing future-oriented images. Participants completed daily and periodic questionnaires to track symptoms. T…

This study tests if group cognitive behavioral therapy (CBT) can reduce anxiety and insomnia in teens aged 12-20. About 171 participants with both conditions will receive either CBT for anxiety or CBT for insomnia. The goal is to see which approach better improves symptoms, sleep…

This study tests whether watching virtual reality videos of mountains, beaches, and waterfalls before coronary angiography can lower anxiety, boost comfort, and improve patient satisfaction. Researchers will compare first-time angiography patients who use VR goggles to those who …

This pilot study tested a digital mental health program called TEPS for teens aged 12-18 with anxiety. Sixty-six participants were recruited from public libraries and randomly assigned to the digital program or usual library services. The study measured how acceptable, usable, an…

This study looked at whether virtual reality exposure therapy can reduce anxiety in people with a fear of flying. 84 participants who were diagnosed with flight phobia and had a smartphone took part. The researchers measured changes in flight-related anxiety using questionnaires …

This study compared two psychological treatments—cognitive behavioral therapy (CBT) and Ericksonian hypnosis—for reducing symptoms of depression and anxiety. 45 adults with symptoms but no formal diagnosis were randomly assigned to CBT, hypnosis, or a no-treatment control group. …

This study tested whether Swedish massage with lavender or chamomile oils can help reduce pain, fear, and anxiety during labor. 90 pregnant women were split into three groups: one got massage with chamomile oil, one with lavender oil, and one with plain carrier oil. Researchers m…

This study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…

This study tested a 22-minute online training program for parents of children aged 5-12 with long-term health conditions. The training taught simple skills based on Acceptance and Commitment Therapy (ACT) to help parents support their child's anxiety. Only 17 parents took part, a…

This study tests whether a new dental anesthesia pen causes less pain and anxiety than a traditional syringe in children aged 6 to 12 who need a filling. Each child will try both methods (with a two-week break in between) so they can compare the experience directly. The goal is t…

This study tested whether transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic fields to stimulate specific brain areas — can improve daily functioning in veterans with PTSD. Researchers compared real TMS to a sham (fake) treatment in 59 veterans.…

This study tests whether wearing virtual reality glasses during femoral sheath removal — a routine step after a heart catheterization — can lower pain, anxiety, and changes in vital signs. About 60 adults undergoing this procedure will be randomly assigned to either use VR glasse…

This study investigates whether laughter yoga can lower stress and improve quality of life for pregnant women diagnosed with gestational diabetes. Participants will practice laughter yoga sessions that combine breathing exercises, clapping, and playful activities. The trial measu…

This study tested whether a 7-minute paced breathing exercise (6 breaths per minute) could reduce anxiety and stress in 30 adults before outpatient GI procedures like colonoscopy. Participants used a noninvasive vibratory device in the waiting room. Researchers measured changes i…

This study looked at whether holding powerful poses before exposure therapy can increase testosterone levels and make treatment for social anxiety more effective. 73 adults with social anxiety disorder participated. The goal was to see if this simple change could help people feel…

This study tested whether D-cycloserine, an antibiotic that helps the brain unlearn fear, can improve cognitive-behavioral therapy (CBT) for social anxiety. 152 adults with social anxiety took either D-cycloserine or a placebo before or after their therapy sessions. Researchers w…

This pilot study tested whether adding a 16-week meditation program to standard cardiac rehabilitation helps people with coronary artery disease feel less stressed and anxious. Forty participants were split into two groups: one did meditation plus rehab, the other did rehab alone…

This study looked at whether teaching cancer patients about their portable chemotherapy pump (elastomeric pump) can make them feel more comfortable and less anxious. 70 adults receiving 5-FU treatment were split into two groups: one got extra education and a booklet, the other go…

This study tests whether adding the blood pressure medication propranolol to cognitive processing therapy (a type of talk therapy) helps people with both post-traumatic stress disorder (PTSD) and alcohol use disorder. About 48 adults aged 18 to 70 with both conditions will receiv…

This study tested whether watching an immersive virtual reality (VR) video during IUD insertion can lower pain and anxiety. 90 women took part, with half using VR and half receiving standard care. The goal was to see if VR offers a safe, simple, drug-free way to improve the exper…

This study tested whether full-spectrum CBD oil can help with anxiety and depression in people with Parkinson's disease. Twenty-seven participants took one of three daily doses (30, 60, or 300 mg) for two months. Researchers measured changes in anxiety and depression scores, alon…

This study tested if a social robot could help children aged 4-12 with chronic diseases feel less fear and pain during a blood draw. 90 children were split into three groups: one that played with a robot, one that played a digital game, and one that received standard care. The go…

This study tested whether watching telenovela-style educational videos can help family caregivers of hospice patients feel more confident and less anxious. 59 caregivers participated over 8 weeks. The approach used weekly video lessons during regular hospice visits.

This study tested whether giving oral probiotics to adolescents before non-cardiac, non-digestive surgeries could reduce anxiety and depression afterward. 150 teens aged 12-17 were randomly assigned to receive either probiotics or a placebo. Researchers measured anxiety and depre…

This study looked at whether art therapy can reduce anxiety and improve mental strength in people with chronic kidney disease who are on hemodialysis. Eighty adults who had been on dialysis for at least six months took part. The results measured changes in anxiety and psychologic…

This study tested a mobile app called EASE to help people manage anxiety and depression during the COVID-19 pandemic. It included 822 adults who identified as Black, Hispanic, or American Indian and had significant anxiety or depression symptoms. The app provided symptom tracking…

This study looked at whether a web-based program called webSTAIR, which teaches skills to manage emotions and relationships, is feasible and helpful for people with PTSD who are on a waitlist for behavioral health treatment. Seventy adults from a hospital clinic in Boston took pa…

This completed trial tested whether a 4-week mindfulness program delivered via smartphone app could reduce anxiety and stress in college students. 289 students participated, practicing daily mindfulness exercises. The study measured changes in anxiety levels and perceived stress …

This study looked at whether giving a special therapy called EMDR to people in the emergency room right after a traumatic event could help prevent post-traumatic stress disorder (PTSD). About 110 adults who were at high risk for PTSD took part. The therapy uses eye movements to h…

This study tests whether cognitive behavioral therapy (CBT) can reduce anxiety and depression in people with inflammatory bowel disease (Crohn's disease or ulcerative colitis). Participants receive either psychologist-led or self-administered CBT over 8 weeks. The goal is to see …

This study tested whether a gentle ear stimulation technique could reduce stress and anxiety in healthcare workers during the COVID-19 pandemic. 62 workers were randomly assigned to receive the stimulation or be placed on a waiting list. The goal was to see if this simple, non-dr…

This study tested a virtual reality app called StoryTelling Medicine (STM) to see if it could reduce anxiety in children aged 8–13 before elective surgery. The app guides kids through hospital settings in a fun, interactive way. Researchers measured anxiety, heart rate, and stres…

This study tested whether professional socio-aesthetics (specialized beauty and well-being care) can improve quality of life, reduce pain, and ease anxiety in adults undergoing chemotherapy for lung, breast, colon, or prostate cancer. 400 participants were randomly assigned to re…

This study tested whether wearing virtual reality glasses during a common kidney stone treatment (ESWL) can lower patients' pain, anxiety, and improve comfort. Seventy adults undergoing the procedure for the first time took part. Researchers measured pain, anxiety, and comfort le…

This study tested whether acupressure—a technique using gentle pressure on specific points on the body—can reduce anxiety, embarrassment, and fear in people undergoing a bladder function test called urodynamics. Sixty-eight adults were randomly assigned to receive either acupress…

This study tested a shorter version of Cognitive Processing Therapy (CPT) for Veterans with PTSD. Many Veterans drop out of the standard 12-session therapy, missing the most helpful parts. The goal was to find which therapy components work best and deliver them in fewer sessions …

This study tested whether listening to Baroque music for 30 minutes could reduce anxiety in 18 adults with major depressive disorder. Participants listened to a specially chosen set of Baroque pieces, and their anxiety levels were measured before and after. The idea is that the m…

This study looked at whether adding a type of talk therapy called prolonged exposure therapy (PET) to standard opioid addiction treatment can help reduce PTSD symptoms. 82 adults with both opioid use disorder and PTSD took part. Some got only addiction treatment, while others als…

This small pilot study tested whether a daily probiotic (Lactobacillus rhamnosus) could reduce abdominal pain and anxiety in children aged 9 to 13. Nine children who had both anxiety and stomach pain took the probiotic for 30 days. Researchers measured changes in pain and anxiety…

This study tested whether using magnetic pulses (rTMS) on the brain while people recall their traumatic memories can reduce PTSD symptoms. 39 adults with PTSD for at least 3 months received either 10Hz or 1Hz rTMS over 2 weeks. Researchers measured changes in PTSD severity using …

This study looked at whether motivational interviewing, a type of counseling that boosts inner motivation, can help nursing students feel less anxious and more confident about their clinical practice. 66 first-year nursing students took part in a randomized trial. The goal was to…

This study looked at whether music therapy can lower anxiety in women with early-stage breast cancer during chemotherapy. Twenty-seven patients took part, with some receiving music therapy sessions while others did not. Researchers measured anxiety levels before and after each ch…

This study tested a type of talk therapy called Behavioral Activation (BA) in 10 U.S. veterans who have both alcohol use disorder and PTSD. BA helps people change their daily activities and thinking to reduce drinking and PTSD symptoms. The study compared BA to another therapy ca…

This study tested a device called Reacor that uses biofeedback to teach mindfulness by showing your heart rate and brain waves in real time. 188 adults with anxiety disorders were split into three groups: biofeedback alone, the medication escitalopram alone, or both together. The…

This study tested a 4-week music program called 'Tuned In' for 133 Hong Kong teens struggling with low mood, anxiety, or loneliness. Participants were randomly assigned to start the program right away or wait 4 weeks. The program, led by a psychologist and music therapist, aimed …

This study looked at whether using a virtual reality hypnosis headset during a frozen embryo transfer is practical and can help lower anxiety. Fifty women undergoing IVF used the headset during the procedure. The main goal was to see if the headset could be used without technical…

This study tested three short, one-time digital sessions (called Project YES) designed to help teens and young adults ages 13-25 who have depression, anxiety, or eating disorder symptoms. Participants completed questionnaires before the session, right after, and again 3 months la…

This study tested whether wearing a virtual reality headset during heart device implantation (like pacemakers) could reduce patients' anxiety and pain. 111 adults were randomly assigned to use VR or standard care. The goal was to see if distraction through VR lowers stress and di…

This study tested an online guided self-help program called EMPOWER for medical professionals with mild depression or anxiety. The program teaches problem-solving and acceptance skills through videos and stories. 161 participants were randomly assigned to the program or a control…

This study tested whether cannabigerol (CBG), a compound from hemp, can improve mood, reduce anxiety, and ease stress. 38 adults who had used cannabis before took CBG or a placebo in a double-blind crossover design. Researchers also tracked side effects like sleepiness and dry mo…

This study tested whether listening to music during a daily cleaning procedure can reduce pain in children aged 6 months to 15 years in a pediatric intensive care unit. Each child experienced the cleaning twice—once with music and once without—and pain was measured using a standa…

This study tested whether wearing virtual reality goggles during the needle stick for dialysis can lower pain and anxiety. Fifty adults on hemodialysis were randomly assigned to either watch VR content during the procedure or receive usual care. The results will show if a simple,…

This study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…

This study tested a 6-week mindful self-compassion program for homeless women with PTSD and substance use. The program includes meditation, group discussions, and home practices. Researchers compared the program to usual care in 202 women living in a residential drug treatment fa…

This study looked at whether having dim light (50-80 lux) in the delivery room can help reduce pain and anxiety during labor. 120 pregnant women in active labor were randomly assigned to either a dimly lit room or standard lighting. Researchers measured pain and anxiety levels at…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were adults aged 18-75 with military-related PTSD and insomnia. The study …

This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help adults with post-traumatic stress disorder (PTSD) in Jordan. 70 people with moderate to severe PTSD symptoms were randomly assigned to receive EMDR from a psychiatric nurse or to a wai…

This study looked at whether painting mandalas during chemotherapy can help reduce anxiety, nausea, and improve comfort. 73 first-time chemotherapy patients took part. One group colored mandalas for at least 30 minutes during treatment, while the other group received standard car…

This study tested whether transcranial magnetic stimulation (TMS), a noninvasive treatment that uses magnetic fields to stimulate brain regions, can improve PTSD symptoms and related brain activity. Fifty adults with partial PTSD received either active TMS or a sham procedure ove…

This study tested a program called RESET, led by community health workers, to improve physical and mental well-being in older adults. Over 450 African American adults aged 50+ with symptoms like depression, anxiety, or chronic pain took part. The program included weekly group pho…

This study tested an online group program called Healthy Minds for people on sick leave due to depression, anxiety, or adjustment disorders. 123 participants either joined the 8-week program or received standard care. Researchers tracked their return to work, symptoms, and job fu…

This study looked at whether hemp-derived cannabinoids can reduce menopause and perimenopause symptoms like hot flashes, anxiety, and mood swings. 104 women aged 40-60 who were not regular cannabis users took part. Researchers tracked their symptoms daily and monthly to see if th…

This study looked at two simple ways to help adults feel less pain and anxiety during a blood draw: doing breathing exercises or squeezing a stress ball. 90 people took part, split into three groups: one did breathing exercises, one used a stress ball, and one had no special tech…

This study tested three ways to deliver Acceptance and Commitment Therapy (ACT) for adults aged 20-40 with mild to moderate PTSD in Pakistan. Participants were split into three groups: standard clinic therapy, clinic therapy with a supporting web app, and fully online therapy wit…

This study tested whether squeezing a stress ball during an ultrasound-guided biopsy can reduce pain and anxiety. 79 adults were randomly assigned to either use a stress ball or receive standard care alone. Researchers measured pain, anxiety levels, and vital signs before and aft…

This pilot study tested a 6-session therapy called Goal-Focused Emotion Regulation Therapy (GET) in 35 young Latino testicular cancer survivors aged 18-39. The therapy helps participants set goals, manage emotions, and find meaning after cancer. Researchers measured anxiety, depr…

This study tested two brief, video-based therapies for women who experienced sexual assault and now struggle with PTSD and heavy drinking. One therapy focused on facing trauma memories, the other on building healthier drinking habits. The goal was to see if these short treatments…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS could help cancer survivors who smoke feel less distressed and smoke fewer cigarettes. 43 participants used the device at home via telehealth. The main goal was to see if people found the dev…

This study tested whether a short, daily Loving-Kindness Meditation (LKM) could help reduce symptoms of depression and anxiety and improve relationships. 240 women college students were randomly assigned to listen to a 5-minute LKM or a visualization meditation each day for one w…

This study tested a brief, community-based psychological program called Problem Management Plus to see if it can reduce depression, anxiety, and distress. Over 1,200 adults with mild to moderate symptoms took part. The program focuses on practical problem-solving skills in just f…

This study tested whether an AI chatbot called Emohaa can reduce symptoms of depression, anxiety, and loneliness in young adults aged 15 to 30. 222 participants with emotional distress were randomly assigned to use the chatbot, receive traditional counseling, or join a waitlist. …

This study looked at whether online laughter therapy could help people on hemodialysis feel less depressed, anxious, and stressed, and improve their quality of life. Sixty-nine adults who were on dialysis took part. They did laughter therapy sessions online. The results showed th…

This study tested whether acupressure, a technique that applies pressure to specific points on the body, can reduce anxiety and improve vital signs like blood pressure and heart rate in people hospitalized with acute coronary syndrome (ACS). Sixty-eight adults with a first-time A…

This study tested two ways to help adults with anxiety and depression become more aware of their emotions and learn to rethink them. One group used a smartwatch to track emotions in real time, while the other reflected on their day each evening. Over six weeks, both groups showed…

This study tested whether a structured education session led by a nurse could lower anxiety and improve quality of life in 188 adults having their first shock wave lithotripsy for kidney stones. The education covered what to expect during the procedure, pain management, and recov…

This study tested whether a short digital task could help NHS staff who kept having unwanted, intrusive memories of traumatic events from working during the COVID-19 pandemic. About 122 healthcare workers took part, using either a memory-competing computer game, a music-listening…

This study tested a program called MOSAIC Plus for pregnant women and mothers of children under 5 who have experienced intimate partner violence and have symptoms of depression or PTSD. The program pairs women with community advocates who provide support and teach skills to impro…

This study looked at whether different intensities of exercise can reduce anxiety in adults with anxiety disorders. 110 sedentary adults with high anxiety sensitivity were assigned to either low-intensity exercise or a program that gradually increased to high-intensity exercise o…

This Phase 3 trial tested whether adding troriluzole to standard OCD medications could reduce symptoms better than a placebo. The study enrolled 589 adults with OCD who had not responded well enough to their current treatment. After 8 weeks, troriluzole did not lead to significan…

This study tested whether aromatherapy with essential oils can reduce anxiety in adults before elective upper limb surgery. 289 participants were randomly assigned to either receive aromatherapy or not. The goal was to see if the scent helped people feel calmer in the operating r…

This study explores whether locally adapted nature-based health interventions can help people with mild to moderate anxiety, depression, or stress. Around 120 adults will take part in weekly outdoor group sessions for at least 10 weeks, focusing on nature interaction, social conn…

This study tested two simple, drug-free methods — squeezing a stress ball or practicing the 4-7-8 breathing technique — to help elderly patients feel less fearful and anxious before an upper GI endoscopy. 75 first-time patients were randomly assigned to one of the techniques, and…

This study tested whether a single dose of BNC210 can quickly reduce anxiety in people with social anxiety disorder. 370 adults took either the drug or a placebo before a public speaking challenge and rated their distress. The goal is to see if BNC210 works as an as-needed treatm…

This study looked at whether multi-family therapy (therapy with several families together) can help teenagers who refuse to go to school because of anxiety. 74 teens aged 12-18 who had been out of school for at least 2 weeks took part. The researchers measured anxiety and school …

This study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…

This study tested whether a 6-week group therapy program (cognitive behaviour therapy) could help reduce anxiety and stress in pregnant women and new mothers. 72 women from Manitoba, Canada, who were pregnant or within 12 months postpartum and had an anxiety disorder took part. T…

This study tested an online psychological service called eClinic for young adults aged 15 to 35 in Hong Kong who have moderate to severe anxiety or depression. The eClinic offers a private, flexible online platform with therapist-guided self-learning modules. Researchers measured…

This study tested whether a simple breathing technique called box breathing can help reduce anxiety, pain, and nausea in patients undergoing a procedure called ERCP. Seventy adults were randomly assigned to either learn the breathing technique or receive standard care. The techni…

This study tested whether teaching children aged 9-12 how to manage their time during haemodialysis can reduce their anxiety and fear. Twenty children were split into two groups: one received the training, the other got usual care. Researchers measured anxiety and fear levels bef…

This study tested whether a smartphone app could help people with PTSD quit smoking and avoid starting again. Participants received counseling, stop-smoking medications, and rewards for not smoking, plus the app. The goal was to see if the app made it easier to stay smoke-free co…

This study tested two relaxation methods—laughter yoga and emotional freedom technique (EFT, a type of tapping)—to see if they could lower anxiety in pregnant women. 120 pregnant women with high anxiety scores took part. The goal was to find simple, drug-free ways to help moms-to…

This study tested whether using a virtual reality clinic (Doxy.me VR) is as good as standard online therapy for treating intense fear of dogs, snakes, or spiders. Fifty-four adults participated, and researchers measured how much their phobia symptoms improved. The goal was to see…

This study tested whether wearing virtual reality goggles during dental sealant placement helps children ages 6-18 feel less anxious and behave better. Each child served as their own control, receiving VR on one side of the mouth and standard care on the other. The researchers me…

This study tested whether using a stress ball and listening to relaxing music during a colonoscopy can reduce pain and anxiety. 100 adults undergoing the procedure without sedation were split into two groups: one used the stress ball and music, the other received standard care. T…

This study tested if hand reflexology massage could reduce fatigue and anxiety in adults with end-stage kidney disease who are on maintenance hemodialysis. 70 patients were split into two groups: one received eight 21-minute hand massage sessions during dialysis over four weeks, …

This study tested a personalized treatment plan for 3 mothers and their young children (ages 4-6) who experienced domestic violence and were living in a shelter. The plan included trauma therapy (EMDR) for the parent and child, plus attachment-based therapy, in an order tailored …

This study tested whether using a stress ball during a non-surgical kidney stone treatment (ESWL) can reduce pain and anxiety. 64 adults having their first ESWL session participated. The stress ball is a simple, cheap tool that distracts the mind. Researchers measured pain, anxie…

This study tested whether watching virtual reality (VR) during foot care could lower pain and anxiety in people with diabetic foot ulcers. 64 adults took part, with half using VR and half receiving standard care. Researchers measured pain, anxiety, and vital signs before and afte…

This study tested an internet-based cognitive behavioral therapy (CBT) program called AMTE for adolescents with anxiety and depression. Sixty teens were randomly assigned to either the online program or a control group. The goal was to see if the program could reduce symptoms of …

This study tested a 3-week program that helps cancer patients identify their personal strengths (like hobbies, social support, or personal qualities) and use them to cope better. 32 adults with different cancers took part in card-sorting sessions, phone calls, and home exercises.…

This study tested whether using a stress ball during local anesthesia for hand surgery can lower anxiety and pain. 74 adults were randomly assigned to either squeeze a stress ball or receive standard care. Researchers measured heart rate variability and self-reported anxiety and …

This completed study tested whether giving children the drug dexmedetomidine during tonsillectomy surgery could reduce pain and agitation afterward. 85 children aged 2-10 took part. Researchers measured pain and anxiety levels after the operation to see if the drug helped compare…

This study tested whether a short, trauma-focused therapy called Narrative Exposure Therapy (NET) can help low-income urban teens aged 16–25 who have PTSD from violence and are at risk for substance use. Researchers measured changes in PTSD symptoms and alcohol use. The goal was …

This study tested whether a 6-session educational program could help people receiving electroconvulsive therapy (ECT) feel less stigma and anxiety about their mental health treatment. Sixty adult inpatients with conditions like depression or bipolar disorder took part. Those who …

This study tested a type of talk therapy called natural psychotherapy, based on Morita therapy and adapted for Chinese culture, in 80 adults with obsessive-compulsive disorder (OCD). The goal was to see if it could reduce OCD symptoms, measured by standard scales. Participants at…

This study tested whether Acceptance and Commitment Therapy (ACT) can improve the well-being of parents caring for children with autism. Thirty parents in Saudi Arabia took part in online ACT sessions over five weeks. Researchers measured changes in stigma, mindfulness, and stres…

This study tested whether using virtual reality before or during total knee replacement surgery could help lower anxiety and improve recovery quality. 120 adults who had the surgery participated. The results showed that VR may be a simple, drug-free way to help patients feel calm…

This study looked at whether playing music of a patient's choice during lumbar interventional procedures (like epidural steroid injections) could reduce pain and anxiety in people with chronic back pain. Thirty adults were randomly assigned to hear music or no music during their …

This study tested whether wearing virtual reality goggles showing relaxing nature scenes and music during IUD insertion could reduce pain and anxiety. 70 women were randomly assigned to either VR or standard care. Researchers measured pain, anxiety, comfort, and vital signs. The …

This study looked at whether Emotional Freedom Technique (EFT), a therapy that involves tapping on specific body points, can reduce pain, pain-related beliefs, and anxiety in people recovering from coronary artery bypass graft (CABG) surgery. Researchers enrolled 66 adults and me…

This study tested a 5-week behavioral therapy for women who experienced sexual assault and use alcohol. The therapy combines writing about the trauma with skills to manage alcohol cravings. Researchers measured changes in drinking habits and PTSD symptoms. The goal is to see if e…

This study tested a remote program called "And Now What?" to help prevent depression and anxiety in new mothers. 128 first-time moms in Chile took part, with some receiving the program plus usual care and others only usual care. The program included educational modules, messaging…

This study tested whether interpersonal psychotherapy (IPT) works as well as two established treatments for chronic post-traumatic stress disorder (PTSD): prolonged exposure therapy and relaxation therapy. 110 adults with chronic PTSD took part, receiving weekly sessions over 14 …

This study tested whether extra psychoeducational nursing sessions could improve quality of life, emotional well-being, and reduce anxiety in 120 adults receiving modified electroconvulsive therapy (ECT) for depression, bipolar disorder, or schizophrenia. Half the patients got th…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This study tested whether listening to nature sounds while walking after gallbladder surgery could reduce anxiety, pain, and stress. Seventy adults who had laparoscopic cholecystectomy took part. Patients walked 50 meters while hearing nature sounds, then returned to bed. Their a…

This study looked at whether a special therapy called EMDR or antidepressant medication (SSRIs) helps people with PTSD grow and recover after trauma. 130 adults with PTSD were randomly assigned to one of the two treatments. The main goal was to see which approach leads to more pe…

This study tested whether wearing a virtual reality mask during blood draws and allergy skin tests helps children aged 7 to 13 feel less pain and anxiety. About 300 kids from two hospitals took part. The goal was to see if distracting them with VR makes these procedures easier to…

This study tested whether adding self-esteem boosts during virtual reality (VR) exposure helps people with fear of heights more than VR alone. 83 adults with fear of heights went through a VR height challenge, with some receiving positive feedback and reminders of past successes …

This study tested a problem-solving therapy program for family caregivers of people with cancer who were receiving palliative care. Over 500 caregivers took part to see if the therapy could reduce their anxiety and depression. The goal was to improve caregivers' emotional well-be…

This study tested a digital program to support the mental health of doctors during the COVID-19 pandemic. 293 physicians from Penn Medicine took part. The program included text messages, resource support, and peer groups. Researchers measured changes in well-being, depression, an…

This completed study tested whether a four-week heart rate variability biofeedback program—simple paced breathing exercises—could help young ethnic minority adults (ages 18-35) with a family history of heart disease manage stress and anxiety. Participants were randomly assigned t…

This completed study tested two common PTSD treatments head-to-head: EMDR therapy (a talking therapy with eye movements) and SSRI antidepressants. Sixty adults with PTSD were randomly assigned to one treatment for six weeks. Researchers measured how many people achieved symptom r…

This study looked at whether adding lofexidine to standard buprenorphine treatment can improve symptoms of both PTSD and opioid use disorder in veterans. 84 veterans on stable buprenorphine therapy were enrolled. The goal was to see if the combination reduced opioid use and PTSD …

This study tested whether a 10-minute virtual reality (VR) relaxation session could help nursing students feel less stressed right before a big exam. Fifty students chose a calming VR scene—like a beach or space—and rated their stress before and after. The goal was to see if this…

This study looked at whether a type of talking therapy called Acceptance and Commitment Therapy (ACT), combined with education about eating, could help female university students who struggle with eating attitudes. 120 students took part, with half receiving the therapy and half …

This study looked at whether adding cannabidiol (CBD) to prolonged exposure therapy can reduce PTSD symptoms in military veterans. 136 veterans took either CBD or a placebo alongside their therapy sessions. The goal was to see if CBD helps improve treatment outcomes.

This study tested whether using bandages printed with cartoon characters helps children feel less fear, stress, and pain during burn dressing changes. 42 children aged 6-11 with second-degree burns were randomly assigned to get either cartoon or plain bandages. The goal was to se…

This study tested whether a guided meditation called yoga nidra is practical and helpful for people with PTSD and insomnia. Sixty adults who had experienced a stressful or traumatic event and had trouble sleeping took part. They listened to online recordings daily for 8 weeks, an…

This study tested three online training components for parents of anxious children aged 7-11. Parents learned to reduce accommodation, respond empathetically, or change unhelpful thoughts about their child's anxiety. The goal was to see which components, alone or combined, best l…

This study tests a therapy called Interaction Guidance Therapy (IGT) for mothers with post-traumatic stress disorder (PTSD) after a traumatic pregnancy or childbirth. The therapy uses video feedback to help mothers become more sensitive to their baby's cues. Researchers will comp…

This study looked at whether guided breathing exercises during labor can lower stress, pain, and anxiety while improving birth satisfaction. 124 pregnant women were split into two groups: one did breathing exercises, the other received routine care. Researchers compared their exp…

This study tested compassion-focused therapy (CFT) in 24 women with complex PTSD who struggle with harsh self-criticism. Over 12 weekly group sessions, participants learned skills to be kinder to themselves. Researchers measured changes in self-criticism, PTSD symptoms, and shame…

This study tested whether a short behavioral program called Acceptance and Commitment Therapy (ACT) could reduce pain and improve function in veterans at risk for persistent pain after knee replacement. 402 veterans were randomly assigned to ACT or an attention control group. Res…

This study looked at whether brief Christian prayer, given in person or virtually, can lower pain and anxiety in adults visiting a family medicine clinic. 180 participants with moderate or higher pain or anxiety were randomly assigned to receive prayer or listen to 5 minutes of r…

This pilot study tested whether a single 2-hour breathwork session could help veterans with PTSD. 36 adults took part in a group training led by a certified instructor, followed by a 30-minute talk with a psychologist. The main goal was to see if the approach was practical and ac…

This study tested short, digital exercises (called micro-interventions) designed to reduce distress and improve well-being in breast cancer survivors. 120 women who had been diagnosed with early-stage breast cancer in the past 5 years and had mild-to-moderate anxiety or depressio…

This study tested a weight management program called MOVE!+UP, designed specifically for veterans with PTSD who are overweight or obese. The program adds extra support to standard PTSD care to help overcome barriers like stress and unhealthy habits. Researchers compared it to the…

This study tested a personalized internet-based program (WebTIPS) to help children ages 1-12 feel less anxious before surgery and recover more smoothly. Over 1,200 parent-child pairs took part, with some using the tailored program and others receiving standard online information.…

This study tested whether virtual peer support groups, co-led by a mental health clinician and a trained peer specialist, could help veterans with serious mental illness (like schizophrenia or bipolar with psychosis) feel more socially connected and less distressed. Twenty-eight …

This study looked at whether mindfulness training could help veterans with PTSD who struggle with anger and aggression. 61 veterans took part. The goal was to see if learning to focus on the present moment could help them control angry feelings and reduce aggressive behavior.

This study tested a new way to help people with social anxiety by training them to replace negative thoughts with positive or neutral ones. 54 university students with high social anxiety were split into two groups: one practiced proactive thought control with AI feedback, the ot…

This study looked at whether Acceptance and Commitment Therapy (ACT), a type of talk therapy, could help university students in Malaysia with mild to moderate anxiety, depression, and stress. 32 students either received six weekly online ACT sessions or were placed on a waiting l…

This study tested whether a 5-minute session of smelling lavender essential oil can help reduce stress, anxiety, and improve satisfaction in emergency department patients. 60 adults admitted to the ER observation unit took part. Half received a lavender-scented tube to sniff, whi…

This study tested a computer program designed to train attention away from threatening faces in 206 youths aged 10-14 with social anxiety disorder. Half received the active training (ABMT) and half a neutral task. The goal was to see if the training could reduce anxiety and chang…

This study tested a version of cognitive behavioral therapy (CBT) that was adapted to fit the cultural background of Canadians of South Asian origin. Researchers worked with 146 adults who had depression or anxiety to see if this tailored therapy could help reduce their symptoms.…

This study tested a version of cognitive behavioral therapy (CBT) that was adapted to be more culturally relevant for Chinese youth in Ontario. 36 participants aged 12 to 21 with anxiety or depression received the therapy from community therapists. The goal was to see if this app…

This study tested a 4-week program called COPE (Coping Options for Parent Empowerment) for parents of teenagers in Spain. The program teaches emotional regulation and positive parenting skills in group sessions. Researchers measured changes in parents' anxiety, depression, stress…

This study tested whether a 5-minute mobile app game could reduce dental anxiety in 114 children aged 7-11 during their first dental visit, compared to the standard tell-show-do technique. Researchers measured pulse rate and anxiety scores before and after the intervention. The g…

This study tested whether low-intensity focused ultrasound, aimed at the amygdala (a brain area linked to emotions), could reduce symptoms of depression, anxiety, bipolar disorder, and PTSD. Twenty-nine adults received daily 10-minute sessions for three weeks. Researchers measure…

This study tested whether Benson's relaxation exercise, a simple technique involving deep breathing and focusing on a meaningful word, could reduce anxiety and fear of movement (kinesiophobia) in 64 people who had total knee replacement. Participants practiced the exercise, and r…

This study tested whether an adapted form of Narrative Exposure Therapy (NET) is acceptable and helpful for adults with mild learning disabilities who have experienced trauma. Thirteen participants completed the therapy, which involved talking through their life events in a struc…

This study tested a group therapy called Cognitive Processing Therapy (CPT) for incarcerated men and women with PTSD. 117 participants were either given the therapy or placed on a waitlist. The main goal was to see if the therapy reduced PTSD symptoms, with secondary goals of red…

This study tested whether a social robot could reduce fear and pain in children aged 5 to 10 during wound dressing. Sixty children were split into two groups: one interacted with the robot while getting their wound dressed, and the other received standard care. Researchers measur…

This study tested a therapy program called 'Being Brave' for children ages 4 to 7 who were at risk for anxiety disorders. The program involved parents and children learning coping skills together. Researchers compared 65 children who received the therapy to those on a waitlist. R…

This study tested whether listening to nada yoga music or squeezing a stress ball can lower anxiety and pain during a Pap smear. 128 women aged 30-56 took part. Researchers measured their anxiety and pain levels before, during, and after the test. The goal was to find simple, dru…

This study tested whether wearing colored glasses (green, red, or blue) for 10 minutes before a tooth extraction could reduce anxiety and pain. 84 adults who had not had a wisdom tooth removed before took part. Researchers measured anxiety using a standard questionnaire and check…

This study tested whether soaking feet in warm water for 20 minutes before pituitary tumor surgery helps patients feel less anxious and keeps vital signs stable. 100 adults were enrolled, with one group receiving the foot bath and the other standard care. Researchers measured anx…

This study tested whether wearing virtual reality glasses during a routine postpartum uterine tone assessment could lower anxiety and pain while increasing comfort. 146 women within 24 hours of giving birth participated. Researchers measured pain with a visual scale and anxiety w…

This study looked at whether using white noise or squeezing a stress ball during a routine fetal heart rate test (NST) can lower anxiety and fear in pregnant women who are scheduled for a planned C-section. 168 women were split into four groups: white noise, stress ball, both, or…

This study tested whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help adults with PTSD from combat or terror. Thirty people who had PTSD for at least 4 years and hadn't improved with standard treatments received 60 daily sessions. Researche…

This study tested whether a 12-session parent-based treatment (Supportive Parenting for Anxious Childhood Emotions) can reduce anxiety in children by changing how their brains respond. 214 children with anxiety disorders participated. The goal was to see if parent training alone …

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) could help young adults aged 18-39 who have cancer or desmoid tumors manage anxiety and depression. The program teaches skills like stress management, goal setting, and positive thinking.…

This study looked at whether hugging and praying during labor can help reduce pain, anxiety, and the feeling of a traumatic birth. 164 pregnant women were offered these comforting actions as often as they wanted during contractions. The goal was to see if simple emotional support…

This study tested a 5-week digital counseling program for 54 women who had a pregnancy loss within the past two months. The program focused on emotional support and coping skills. Researchers measured grief and stress levels before, right after, and up to 6 months later to see if…

This study tested a program called ENCODE designed to help family caregivers of people with dementia manage stress and communicate better about pain. 452 caregivers were randomly assigned to either the ENCODE program or friendly video calls. The goal was to see if the program imp…

This study tested a group-based writing therapy for Chinese teenagers with PTSD or complex PTSD. 53 teens took part, with some receiving the therapy right away and others placed on a waiting list. The therapy involved 5 to 8 group sessions where participants wrote about their tra…

This study tested a counseling program called the Friendship Bench for 106 teens aged 13-18 who have HIV and feel depressed or anxious. The program aims to improve their mood and help them stay engaged in their HIV care. Researchers measured how well the program worked by looking…

This study tested whether letting patients watch their own ACL reconstruction surgery live on a screen helps them feel less afraid of moving after the operation. 65 adults having ACL surgery under spinal anesthesia either watched the procedure or received standard care. The goal …

This pilot study tested a short psychological program called Problem Management Plus (PM+) in 64 refugees and asylum seekers in Switzerland. The program, developed by the World Health Organization, uses simple techniques like problem-solving and stress management to reduce psycho…

This study tested a brief form of cognitive behavioral therapy (bCBT) for Veterans with anxiety. 225 Veterans from three VA medical centers received either bCBT (in-person or by video) or usual care. The goal was to see if this short therapy helps reduce anxiety symptoms better t…

This study tested a 30-minute web-based program for parents of children with anxiety who are waiting for cognitive behavioral therapy. The program aims to reduce how much parents accommodate their child's anxiety, which can make anxiety worse. Researchers recruited 47 parents and…

This study tested a school-based mental health program for teenagers with mild to moderate stress, anxiety, or depression. The program uses acceptance and commitment therapy (ACT) to help teens become more flexible and resilient. Sixty-one students took part in four group session…

This study tested a brief virtual therapy called MAPP (Mindful Adaptive Practice in Pregnancy) to help pregnant women manage COVID-19-related anxiety. 69 women participated, comparing MAPP to usual care. The goal was to see if the therapy is feasible and acceptable, not yet to pr…

This study tested whether methylone, a substance similar to MDMA, can safely reduce PTSD symptoms in adults. 79 participants with moderate to severe PTSD received either methylone or a placebo once a week for four weeks, then were followed for six more weeks. The goal was to see …

This study tested whether using virtual reality (VR) before a first-time heart catheterization could lower anxiety more than just standard education. 180 adults were split into two groups: one got VR plus education, the other only education. Anxiety was measured with a standard q…

This study tested a new psychological treatment for autistic young people who struggle with overwhelming sensory experiences, like sounds or lights. Twenty-five participants completed a group therapy program and did tasks before and after to see if their brain responses and anxie…

This study tested a wearable device called NightWare that uses an Apple Watch to detect when a person is having a nightmare and gently vibrates to wake them just enough to stop the nightmare without fully waking them. The trial included 270 veterans and active-duty service member…

This small study tested whether shining special LED lights on the head could help veterans with mild traumatic brain injury (TBI) and PTSD think more clearly and feel better. Eight veterans received the noninvasive light treatment, and researchers measured changes in memory, atte…

This study tested whether structured educational sessions could reduce tokophobia—an intense fear of pregnancy and childbirth—in 50 pregnant women in Egypt. The program included five sessions covering causes, coping strategies, and lifestyle tips. Researchers measured changes in …

This study tested a handheld device called CalmiGo in 35 adults coming to the emergency department with anxiety or panic attacks. The device uses guided breathing, aromatherapy, and grounding techniques to help people relax without medication. Researchers measured symptoms before…

This study tested whether aromatherapy with lavender and peppermint essential oils can reduce nausea and anxiety in cancer patients during chemotherapy infusions. Forty adult outpatients who reported nausea or anxiety were given a gauze with one to two drops of oil to sniff as ne…

This study tested a new, non-invasive treatment for major depression called transcranial photobiomodulation (tPBM), which uses near-infrared light on the scalp. Fifty adults with depression received either real light therapy or a sham treatment three times a week for six weeks. T…

This study tested a digital mental health app designed to help young adults (ages 18-25) who engage in nonsuicidal self-injury and are not currently in treatment. The app provides psychoeducation, skill-building exercises, and daily check-ins. Researchers compared a self-guided v…

This study tested whether a social robot named PARO could help children with rare diseases and their parents feel less anxious and stressed, and improve their relationship. Fourteen families completed four sessions where they interacted with the robot together. The results showed…

This study tested a mindfulness-based program (including breathing exercises and meditation) in 39 Generation Z nursing students during their clinical internship. The goal was to see if it could improve mental health and reduce anxiety, depression, and stress compared to usual ca…

This study looked at whether a short virtual reality mindfulness session could help patients feel less anxious and stressed after heart surgery. 34 adults who had heart bypass or valve repair took part. One group did a 15-minute VR mindfulness exercise, while the other group rece…

This study tested a 4-week nursing program based on self-efficacy theory for 300 lung cancer patients receiving CyberKnife radiation. The program included education, psychological support, and self-management training. Researchers measured changes in anxiety, pain, and quality of…

This study tested a program called EMPOWER for veterans who completed trauma-focused therapy for PTSD and saw improvement. The program includes a workbook and four therapist check-ins over 12 weeks to help veterans manage symptoms on their own. Researchers wanted to see if it cou…

This study tested whether a program combining behavioral activation (helping people do meaningful activities) and medication optimization (adjusting meds) can reduce depression and anxiety in adults 60 and older undergoing heart surgery. 105 participants were split into two group…

This study tested a program that combines counseling (behavioral activation) with medication adjustments to reduce depression and anxiety in adults aged 60 and older who were scheduled for hip or knee replacement surgery. 116 participants were randomly assigned to receive the pro…

This study tested whether wearing earplugs and an eye mask during an MRI scan can lower anxiety. 72 adults having their first MRI were split into two groups: one used the earplugs and eye mask, the other did not. Researchers measured changes in blood pressure, heart rate, breathi…

This study tested an experimental drug called ENX-102 in 47 adults with social anxiety disorder. Participants received either the drug or a placebo to see if it reduced fear and avoidance in social situations. The goal was to measure safety and how well the drug works as a standa…

This study tested whether a gentle arm massage with sesame-lavender oil can reduce acute pain and anxiety in women after mastectomy surgery. 90 women were randomly assigned to receive massage with either sesame-lavender oil, plain sesame oil, or paraffin oil (a placebo). The goal…

This study looked at whether smelling lavender essential oil for 20 minutes before orthopedic surgery could lower anxiety, stress, and depression. 128 adults in Jordan took part, with half inhaling lavender oil and the other half receiving usual care. Results showed that the lave…

This small study tested whether 8 sessions of brief exposure therapy combined with moderate exercise can reduce PTSD symptoms in adults. Twelve participants attended twice-weekly sessions for 4 weeks and completed questionnaires. The goal was to see if this treatment is acceptabl…

This study tested a 360-degree virtual reality (VR) app to help first-year medical students prepare for their first cadaver dissection. 43 students used the VR app or traditional methods, and researchers measured their anxiety levels. The goal was to see if VR could make the expe…

This study tested whether using virtual reality (VR) can help reduce pain and anxiety in people recovering from heart surgery, specifically when chest tubes are removed. 200 adults who had just had heart surgery were given either VR or nitrous oxide (laughing gas) during the proc…

This study tested whether a simple technique called progressive muscle relaxation training can reduce symptoms of post-traumatic stress disorder (PTSD) in people affected by the February 6 Kahramanmaraş earthquake. 44 adults with PTSD took part. The training involves tensing and …

This study tested whether guided breathing exercises (4-7-8 breathing and diaphragmatic breathing) can help reduce pain, anxiety, and improve comfort during the needle insertion for dialysis. 90 adults on hemodialysis were split into three groups: two doing different breathing ex…

This study tested two remotely delivered programs—mindfulness-based cognitive therapy and internet-based cognitive behavioral therapy—against standard remote monitoring alone for reducing depression and substance use related to COVID-19 stress. 113 adults from a health system par…

This study tested whether applying acupressure to a specific point on the hip for one minute before an intramuscular injection could reduce pain, fear, and improve satisfaction. Sixty-eight adults receiving a diclofenac shot were randomly assigned to acupressure or standard care.…

This study tested whether using virtual reality hypnosis before chemotherapy infusions could lower anxiety in men with metastatic prostate cancer. Fifty-three patients were randomly assigned to either receive the VR hypnosis session or standard care before each docetaxel infusion…

This study tested whether watching calming nature scenes together in virtual reality could help hospice patients and their caregivers feel better. 26 patient-caregiver pairs tried the shared VR experience. Researchers measured changes in quality of life, fear of death, and pain, …

This study tested whether using a virtual reality relaxation headset during orthodontic bonding (getting braces put on) can lower anxiety in teens and adults. 62 participants were randomly assigned to either use the VR headset or not. Researchers measured anxiety through question…

This study tested a constipation training program for mothers of children aged 4-6 with functional constipation. The program used motivational interviewing to help mothers manage their child's condition. Researchers measured changes in children's bowel movements and stool consist…

This study tested a mobile app called PCYCARE in 120 first-time pregnant women in their third trimester. The app provides educational modules and guided relaxation sessions over 21 days. Researchers measured changes in anxiety, sleep quality, and childbirth preparedness compared …

This study tested a stress management program for nursing students aged 18-25 who had mild to moderate depression. The program taught cognitive-behavioral skills to handle stress. Students who took part reported lower levels of depression, anxiety, and stress compared to those wh…

This study tested an 8-week online program to help people with multiple sclerosis (MS) improve their problem-solving and coping skills. The goal was to see if the program was easy to use and if it helped reduce anxiety and depression. Thirty adults with MS in Lebanon took part. T…

This pilot study tested whether a 12-week course of a synbiotic supplement (probiotics plus prebiotics) could help reduce anxiety in 30 children with autism spectrum disorder. The main goals were to see if the treatment was safe and tolerable, and to measure any changes in anxiet…

This study looked at whether distracting boys aged 7-10 with a goldfish or a kaleidoscope while they are being taken to the operating room for circumcision can help reduce their fear, anxiety, and pain, and make them more comfortable. Researchers compared these two fun activities…

This study tested a new type of therapy called reminder-focused positive psychiatry (RFPP) for teenagers who have both ADHD and PTSD. The goal was to see if the therapy is acceptable and helpful for reducing symptoms. Eleven teens took part, and the study measured how well they l…

This study tested a therapy called Cognitive Behavioral Therapy for Work Success (CBTw) in 294 veterans with serious mental illness (like depression, bipolar disorder, or PTSD) who were unemployed. The goal was to help them find and keep competitive jobs, which can improve their …

This study tested a 5-week online group program called Rare Group Problem Management Plus (PM+) for parents of children with rare diseases. The program teaches stress management and problem-solving skills to help reduce anxiety, depression, and distress. Eight parents participate…

This pilot study tested a wearable device that gently stimulates a nerve in the ear to help manage anxiety in teenagers with autism. Ten participants used the device at home twice daily for four weeks. The goal was to see if it was safe and easy to use, not yet to prove it works.…

This study tested whether prazosin, a drug used for high blood pressure and PTSD nightmares, can reduce headaches in veterans and service members who had a mild traumatic brain injury. 89 participants received either prazosin or a placebo for 12 weeks. Researchers tracked headach…

This study tested whether a type of compassion meditation could help Veterans with chronic pain who also have depression or PTSD. 142 Veterans were randomly assigned to either compassion meditation training or a health education group. The goal was to see if meditation could redu…

This study looked at whether a 10-week compassion meditation course is a practical and acceptable treatment for veterans with PTSD. Researchers enrolled 113 veterans across multiple U.S. sites and compared the meditation program to a standard relaxation course. The main goal was …

This study tested whether a program that combines behavioral activation (a type of counseling that helps people engage in meaningful activities) with medication optimization (reviewing and adjusting current medications) can reduce anxiety and depression in adults aged 60 and olde…

This study tested whether a cannabidiol (CBD) solution placed under the tongue could help adults with moderate to severe anxiety. 46 participants took either full-spectrum CBD, single-compound CBD, or a placebo three times daily for four weeks, alongside their usual treatments. R…

This study tested a program where parents and children prepare together before surgery to see if it lowers children's anxiety when they get anesthesia. Fifty children aged 5 to 12 having planned surgery took part. The program involved parents being present and prepared for the op…

This study tested a personalized version of cognitive processing therapy (CF-CPT) for veterans with PTSD. 179 veterans participated to see if tailoring therapy to individual needs improves daily functioning, quality of life, and treatment completion compared to standard therapy. …

This study tested two brief mental strategies—reconstrual and repurposing—to see which better reduces sadness and anxiety in 233 young adults aged 18-30. Participants read an emotional story, then practiced one of the strategies and rated their feelings. The goal is to find simpl…

This study tested two simple play activities—bubble breathing and tell-show-do (a storytelling technique)—to see if they could reduce anxiety in children aged 5-12 and their parents before elective surgery. 210 families participated, and their anxiety levels were measured before …

This study tested whether wearing virtual reality glasses or listening to white noise (rain sounds) can reduce pain and anxiety during IV insertion in adults. 76 participants were randomly assigned to one of three groups: VR, white noise, or standard care. Pain and anxiety were m…

This completed study tested whether wearing a special graphene cap that emits far-infrared heat could improve thinking and mood in older adults with mild cognitive decline or Alzheimer's. 126 participants were split into groups based on their cognitive level and received either t…

This study measured how common anxiety and depression are in adolescents with polycystic ovary syndrome (PCOS). 42 teens took a combined oral contraceptive daily for six months. Researchers tracked changes in depression scores to see if the pill improved mood along with PCOS symp…

This study tested two types of mental exercises in 514 older adults with mild to moderate Alzheimer's disease. One group used a computer program with brain games, while the other used physical puzzles and memory cards. The goal was to see if these activities could improve thinkin…

This study tested whether a probiotic called Lactobacillus rhamnosus GG can reduce inflammation and PTSD symptoms in veterans. Researchers enrolled 383 veterans with PTSD and gut issues, giving them either the probiotic or a placebo. The goal was to see if calming inflammation in…

This study tested whether playing a recording of a mother's voice to children as they wake up from anesthesia can reduce postoperative delirium. Eighty children having tonsil surgery took part. Half heard their mother's reassuring voice during recovery; the other half did not. Re…

This study looked at whether 6 months of supervised exercise training could reduce PTSD symptoms and improve physical health in older veterans with PTSD. 80 veterans took part, with one group doing exercise and another receiving health education. The goal was to see if exercise c…

This study tested a faith-based mobile app called PRAY.COM to see if it helps university students feel better mentally and emotionally. About 450 students used the app for at least 10 minutes each day over 8 weeks. Researchers checked if students liked the app and used it regular…

This study tested a 9-week online mindfulness program for teens aged 12-17 with anxiety or depression. Half of the teens also had a parent or caregiver join the program. Researchers wanted to see if adding a caregiver improved the teen's symptoms. The study was very small (32 par…

This study tested whether psychological interventions can reduce anxiety in women about to undergo egg retrieval with general anesthesia. 180 women participated, with some receiving the intervention and others not. Researchers measured anxiety using a questionnaire just before th…

This study tested a brief, self-guided internet-based cognitive behavioral therapy (iCBT) program designed for university students, researchers, and staff. The program includes four weekly modules to help manage stress and anxiety. Researchers enrolled 35 participants to see if t…

This study tested a group writing therapy for Chinese teenagers with PTSD. 53 teens took part, with some getting the therapy and others on a waiting list. The goal was to see if writing about their trauma in a group setting could ease PTSD symptoms. Results suggest it may help, b…

This study tested whether tailored online writing exercises could help sexual minority women, transgender, and nonbinary people who have experienced trauma. The goal was to reduce PTSD symptoms and heavy drinking. 131 participants completed the writing program and were followed f…

This study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…

This completed Phase 1 trial tested transcranial direct current stimulation (tDCS) in 42 adults with obsessive-compulsive disorder (OCD). Participants received 10 sessions of either low-dose, higher-dose, or fake (sham) electrical stimulation over five days. The goal was to see i…

This study tested whether listening to positive affirmations along with classical music during a cesarean section could lower anxiety and improve breastfeeding. 99 women were split into three groups: one listened to affirmations with music, one listened to music only, and one had…

This study tested whether acupressure—a technique using finger pressure on specific body points—can improve pain, anxiety, sleep quality, and the sense of nursing presence in intensive care patients. Sixty adults in the ICU were split into three groups: one received real acupress…

This study tested whether a trained nurse using 'hypnotic communication'—a calm, supportive way of talking—could help men feel less anxious and experience less pain during a prostate biopsy. One hundred men were randomly assigned to receive either standard care or standard care p…

This small study tested a structured mindfulness program for adults with both substance use disorder and anxiety. Three participants completed the program to see if it was feasible and could help reduce stress and anxiety. The study focused on emotional awareness and coping skill…

This study looked at whether breathing a 50:50 mix of oxygen and nitrous oxide (laughing gas) can reduce pain and anxiety in children aged 1 to 16 during minor procedures like blood draws, stitches, or tube placements. Researchers observed 100 children and measured their pain usi…

This study tested whether wearing a virtual reality headset showing a nature video could reduce pain and anxiety in 90 adults undergoing coronary angiography, a heart procedure where patients are awake. One group watched the VR video during the procedure, while the other received…

This study looks at how the brains of children aged 9 to 12 with anxiety disorders respond to making mistakes. Researchers measure two types of brain activity: one after an error and one after a balance disturbance. Half of the children will use a 45-minute computer program desig…

This study looked at levels of a specific enzyme, α-N-acetylgalactosaminidase, in the blood of people with panic disorder who had never taken medication. Researchers compared these levels to healthy individuals and checked for connections with symptom severity and inflammation. T…

This study tested whether three weekly sessions of basic disaster awareness education could improve disaster literacy and reduce earthquake anxiety in adolescents aged 10-14. A total of 128 students from two middle schools in Erzincan took part, with half receiving the education …

This completed study looked at how well a collaborative care model works for common mental health issues like anxiety and depression in four French health clinics. The model involves a care manager who coordinates between family doctors and mental health specialists. Researchers …

This study developed and tested a new questionnaire called the Excessive Emotional Behaviors Scale (EEBS) for Chinese adults experiencing anxiety or depression. Researchers interviewed 18 people and surveyed 637 participants to refine the scale, which measures behaviors like avoi…

This study looked at whether brain activity patterns can predict how well people with major depression or social anxiety respond to cognitive behavioral therapy (CBT). Over 200 participants were randomly assigned to 12 weeks of CBT or supportive therapy. Researchers measured brai…

This study tested whether a role model-based ethics course could reduce moral injury and stress in 101 second-year medical students in Taiwan. Students chose between a standard version with stories and handouts, or an enhanced version with extra writing and guest speakers. Resear…

This study looked at 6 children with past PTSD to see if changes in attention and memory could predict a relapse. Researchers used computer tasks and standard tests to measure brain function. The goal is to find early warning signs so families can get help sooner.

This study looks at 65 veterans with PTSD who use cannabis frequently. Researchers want to see if reducing cannabis use improves their daily functioning, mental health, and quality of life. No treatment or drug is given—participants simply report their cannabis use and well-being…

This study compared two types of orthodontic appliances—removable braces and clear aligners—in 24 children aged 6 to 12 with crossbite. Researchers measured changes in speech, oral hygiene, pain, anxiety, and quality of life over two weeks. The goal was to understand how each app…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages, including children as young as 8, to track patterns of these conditions over time.…

This study surveys anesthesiologists to explore whether feelings of being a fraud (impostor phenomenon) are linked to everyday memory and attention lapses. Participants complete online questionnaires about impostor feelings, cognitive failures, anxiety, depression, sleep quality,…

This study tested whether using augmented reality (AR) or a 3D hip model helps first-year nursing students learn how to give intramuscular injections better than traditional methods. 146 students were randomly assigned to practice with AR, a 3D model, or a standard model. Researc…

This study looked at 40 people having both wisdom teeth removed, two weeks apart. Researchers measured two natural chemicals in the blood—serotonin and kynurenic acid—before and after surgery to see if they relate to pain and anxiety. The goal was to better understand how these c…

This study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…

This study tested whether oxytocin nasal spray helps people with social anxiety disorder learn safety from watching others. About 120 adults received either oxytocin or a placebo and underwent brain scans. The goal was to see if oxytocin improves the brain's ability to tell threa…

This study surveyed 186 adults with sickle cell disease in the U.S. to learn how the COVID-19 pandemic impacted their stress, anxiety, pain, and healthcare use. Participants completed online questionnaires about their medical history, mental health, and experiences during the pan…

This completed study looked at 1,740 newly married couples to see if the bacteria in their mouth, eyes, and gut are linked to sleep problems, vision issues, and mood. Participants provided samples and completed surveys about sleep, anxiety, depression, and dry eye symptoms. The g…

This study follows couples who gave birth in either a midwifery-led birth unit or a standard obstetric unit in France. Researchers want to see if the type of care affects parents' mental health, especially post-traumatic stress, and the child's development up to two years later. …

This study compared two types of radiation for people with 11 to 20 brain tumors that spread from other cancers. One group got Gamma Knife radiosurgery, which targets each tumor precisely. The other got whole brain radiation, which treats the entire brain. The goal was to see whi…

This study looked at whether an adaptive e-learning course on urgent medical conditions could reduce anxiety and improve skills in junior doctors starting work in emergency departments. 233 new doctors were randomly assigned to either take the course in their first six weeks or r…

This study tested a coaching program for doctors to improve communication with Black and Latinx families during hospital rounds. The program taught doctors to be more respectful, collaborative, and trauma-aware. Researchers measured whether families felt more trust and satisfacti…

This study looked at 103 adults with narcolepsy or obstructive sleep apnea to see if anxiety, social, or work factors affect their ability to stay awake during a standard test. Participants filled out an anxiety questionnaire before the test. The goal is to better understand why …

This study gave 100 healthy adults either 50 mg of CBG or a placebo to see how it affects anxiety, stress, mood, memory, and physical signs like heart rate and blood pressure. Researchers also tracked side effects like sleepiness or dry mouth. The goal is to better understand bot…

This study tested whether daily mood check-ins via a mobile app could help predict and prevent depression in people who recently had a stroke. Over 400 participants used the app for three months while researchers tracked their emotional symptoms. The goal was to see if this kind …

This study followed nearly 10,000 Stanford undergraduates over their college years to understand how social ties, loneliness, and stress relate to anxiety and depression. Researchers used surveys and social network analysis to track changes in mental health. The goal is to create…

This study tested a program called Multi-Family Healing Spaces for families affected by the Rwandan genocide. 319 family members aged 12 and older from five districts took part. The program aimed to improve family communication, resilience, and mental health. Results will show if…

This study tested a web application called PRATICAdr 2.0, designed to help healthcare workers on sick leave due to common mental disorders like depression or anxiety return to work. The app helps coordinators track progress and improve communication. Researchers compared workers …

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This study looked at how the brain and heart respond to stressful images and sounds in women who have had multiple pregnancy losses and also have anxiety. Researchers used special head sensors and heart monitors to measure these reactions in 70 women. The goal was to find pattern…

This study tested whether a single 15-minute session of Butterfly Tapping, a self-administered EMDR technique, could change brain activity in 46 young adults with PTSD. Participants either did the tapping or sat still while their brain waves were recorded. The tapping group showe…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study examines how often patients and their relatives develop post-traumatic stress disorder (PTSD) after a sudden cardiac arrest. Researchers interviewed 45 people (20 survivors and 20 relatives) within a week of the event and again at 3 months using standard questionnaires…

This study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…

This study looked at whether a virtual reality (VR) education program could help first-time radiation therapy patients understand their treatment better and reduce anxiety and depression. 84 cancer patients were split into two groups: one received VR education, the other standard…

This study looked at 202 Polish adults with chronic low back pain to find out how severe their anxiety symptoms are. Participants filled out a questionnaire called GAD-7, which scores anxiety from none to severe. The goal was simply to measure the problem, not to test any treatme…

This study tested whether offering tai chi classes online is a practical way to help veterans with PTSD and chronic pain. Researchers worked with 42 veterans to see if they would attend sessions and find the program satisfactory. The goal was to gather information needed to desig…

This study looked at how often older adults feel anxious or depressed after breaking a bone from a fall and having surgery. Researchers used a simple questionnaire to check symptoms in 40 patients aged 65 and older, both those who had surgery and those who did not. The goal was t…

This study tested a 10-item questionnaire called DEPITAC, designed for nurses to screen road traffic accident patients for post-traumatic stress disorder (PTSD) while they are still in the surgical unit. Researchers enrolled 274 hospitalized accident victims to see if the simple …

This study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…

This study aimed to find simple ways to predict how much pain people will feel after oral surgery, like having a tooth pulled. Researchers measured things like pain sensitivity before the procedure in 148 adults. The goal was to create a model that helps doctors plan better pain …

This study looked at how people with PTSD pay attention to their surroundings. Researchers used a change blindness test to see if patients are quicker to notice changes, especially emotional ones. 80 adults with PTSD and healthy controls participated. The goal was to understand t…

This study looked at 38 people who had a first stroke in the cerebellum, a brain area involved in mood. Researchers used interviews and smartphone tracking to measure depression, anxiety, and apathy in daily life. The goal was to better understand how these mood problems develop …

This study tested whether a training program called Modeling to Learn (MTL) helps clinic staff improve how many veterans start and finish evidence-based treatments for PTSD, depression, and opioid use disorder. The program uses computer simulations to let staff try out changes to…

This completed study looked at 168 adults with a history of trauma to see if PTSD harms blood vessel function, which could raise heart disease risk. Participants completed behavioral tasks measuring fear and attention, and had their blood vessel health checked. The goal is to und…

This study looked at why Interpersonal Psychotherapy (IPT) helps people with PTSD. Unlike most PTSD therapies, IPT does not involve re-living traumatic memories. Instead, it focuses on improving relationships and emotional awareness. Researchers measured emotional awareness in 29…

This study looks at 128 children who were part of an early intervention program in infancy and are now teenagers. Researchers measure brain activity, stress responses, and behaviors like risk-taking and mood to see if early help made a difference. No new treatment is given; this …

This study looked at 60 teens ages 12 to 18 to see if those with Avoidant and Restrictive Food Intake Disorder (ARFID) had more feeding problems before age 4 compared to healthy teens. Researchers used questionnaires to check early feeding history, growth, and sensory sensitiviti…

This study looked at 60 women who had surgery for borderline or benign ovarian tumors. Researchers used questionnaires to measure anxiety, depression, body image, and sexual health. The goal was to understand the emotional and psychosexual impact of a borderline tumor diagnosis c…

This completed Phase 3 substudy looked at whether MDMA-assisted psychotherapy can change how stress-related genes work in people with PTSD. Researchers collected saliva samples from 45 participants before and after treatment to measure changes in gene activity. The goal was to se…

This study looked at how the COVID-19 pandemic affected the mental health of 193 Amish and Mennonite adults who already had depression, anxiety, or bipolar disorder. Participants filled out surveys about their symptoms and pandemic-related stress over two years. The goal was to u…

This small study tested whether a gentle brain stimulation technique called HD-tDCS could improve the effects of cognitive behavioral therapy (CBT) for people with depression, anxiety, or PTSD. Twenty participants received either real or fake stimulation daily for five weeks whil…

This study looked at whether adding specialty palliative care early on to standard intensive care can improve the experience for critically ill older adults (age 60+) and their families. Over 1,000 patients and their family members took part. The goal was to see if this approach …

This study in Cameroon tested whether training healthcare workers improves how they screen and manage post-traumatic stress disorder (PTSD) in road traffic injury patients. Researchers trained staff at one hospital and measured changes in knowledge and screening rates over six mo…

This study looked at a telemedicine program called TOP that helps rural veterans with PTSD get care without traveling far. Over 500 veterans took part. The goal was to see which method of rolling out the program worked better to reach more patients and improve PTSD symptoms.

This study looks at whether forgiving people's medical debt can improve their mental health, reduce anxiety and depression, and help them get the medical care they need. Over 15,000 adults who owed medical debt were randomly selected to have their debt forgiven by a charity. Rese…

This completed study followed over 7,500 Chinese patients aged 65 and older who had non-cardiac surgery. Researchers measured how many developed anxiety or depression symptoms afterward using standard questionnaires. The goal was to find out how common these symptoms are and what…

This study surveyed over 750 adult patients before elective surgeries to learn about their anxiety and find out which calming methods they find helpful. Participants answered anonymous questionnaires about their feelings and preferences. The goal was to gather information to impr…

This completed study from the University of Toronto looked at whether certain gut bacteria are linked to anxiety, depression, and panic disorders. 500 adults provided stool samples to test for H. pylori and other bacteria. The goal was to understand possible root causes, not to t…

This study looked at whether a 5-session class teaching cognitive behavioral therapy (CBT) skills can increase a brain pattern linked to resilience against PTSD. It involved 30 public safety personnel (like police or firefighters) who were already in a larger study. Researchers u…

This study looked at three digital coping strategies—reappraisal, distraction, and relaxation—to help children aged 9-12 whose parents are separated or divorced. The goal was to see which tools best reduce anxiety, depression, and behavior problems. 148 children and a parent took…

This study looked at 22 adults with spinal cord injury to understand whether anxiety or physical discomfort causes changes in heart rate and blood pressure during bladder catheterization. Participants either did the procedure themselves or had a nurse do it, with some not knowing…

This study compared Kahoot-based quizzes to traditional paper quizzes in 131 physiotherapy students over 4 weeks. Researchers measured test anxiety, stress coping, and motivation. The goal was to see if gamified learning could improve student well-being.

This study looked at how electrical brain stimulation influences approach and avoidance behavior in 13 patients with deep brain stimulators for OCD, depression, or epilepsy. Participants played a computer task with their stimulator turned on and off. The goal was to understand br…

This pilot study adapted a behavioral intervention called BECOME to help people with dementia or mild cognitive impairment and their caregivers manage non-communicable diseases (like diabetes and high blood pressure) and common mental health conditions (like depression and anxiet…

This completed study looked at how constant noise in intensive care units (ICUs) affects healthcare workers. Researchers compared 102 ICU and ward staff on hearing, anxiety, and noise sensitivity. The goal was to see if long-term exposure to ICU noise is linked to health problems…

This study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…

This study looked at how anonymity and data privacy affect the success of online therapy for social anxiety. Over 450 adults used either a fully anonymous or a standard version of a digital self-help program. The goal was to see if privacy options change how well the therapy work…

This study looked at whether simulation-based training for vaginal exams helps midwifery students feel less anxious and more confident. 67 third-year students were split into two groups: one practiced on a simulator in a lab, the other in a real clinical setting. Results showed t…

This study tested whether a special 4-step teaching method (called the Peyton model) helps midwifery students learn prenatal care better than standard training. 64 students were split into two groups and tested on their knowledge, skills, confidence, anxiety, and satisfaction. Th…

This study looked at how children ages 8 to 17 use smartphones and tablets, including social media and games, and how that relates to their mental health, sleep, and physical activity. Over 900 children and their parents used the Aura app and completed surveys for three months. T…

This study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…

This study tested whether holding a newborn skin-to-skin right after a C-section (within 5 minutes) or within the first hour helps with breastfeeding, reduces anxiety, and keeps mom and baby healthy. 92 mothers and their newborns took part. The results showed that early contact c…

This study looked at whether watching short science videos can change how adults with anxiety think about psychological therapy. 262 participants watched 30 minutes of educational videos and filled out surveys about their beliefs and expectations. The goal was to understand if sc…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group t…

This study looked at 120 adults to see if anxiety and depression are linked to a common tooth infection called apical periodontitis. Participants had dental exams and filled out questionnaires about their mental health. The goal was to better understand how emotional well-being a…

This study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…

This study looked at whether levels of certain minerals (like selenium, magnesium, and zinc) in the blood are different in women with fibromyalgia compared to healthy women. It also checked if those mineral levels are linked to how severe the disease is, or to anxiety and depress…

This study monitored the sleep of 48 veterans with trauma-related nightmares using in-home devices. Researchers aimed to understand how nightmares affect sleep and how they change with cognitive-behavioral therapy. The goal is to improve personalized care for veterans suffering f…

This study measured anxiety in 300 adults before they underwent allergy testing. Researchers used a simple 0-to-10 scale and a questionnaire to gauge how anxious patients felt. The goal was to better understand what affects a patient's experience and how anxiety might influence t…

This study tested whether a one-hour class on climate change and pregnancy could help pregnant women feel more aware, less anxious, and more hopeful about the future. 154 pregnant women were split into two groups: one received the class, the other did not. Researchers measured th…

This study looked at whether a simulation-based lab program could help nursing students feel more competent and less anxious when caring for children. Sixty third-year nursing students took part. The program included hands-on practice with tasks like taking vital signs, hygiene c…

This study looked at how parents cope emotionally after their child is hospitalized in intensive care for a severe injury. Researchers checked for signs of anxiety, depression, and post-traumatic stress in 62 parents, 3 to 6 months after the child left the ICU. The goal was to un…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study looked at how psychological trauma affects memory and brain function in teenagers with post-traumatic stress disorder (PTSD). Researchers used MRI scans to compare brain activity in 19 adolescents with PTSD and healthy teens. The goal was to understand the brain areas …

This completed study from the National Institute of Mental Health surveyed over 3,600 English-speaking adults online every two weeks for six months. Researchers asked about mental health symptoms, stress, and behaviors during the COVID-19 pandemic. The goal was to understand how …

This study tested an AI tool called LyssnCBT that listens to therapy sessions and gives therapists feedback on how well they are using cognitive behavioral therapy (CBT). Researchers worked with 449 therapists, supervisors, and clients at five community mental health agencies in …

This completed study looked at how common depression and anxiety are in teenagers with cystic fibrosis and their parents. Researchers used questionnaires during routine clinic visits to screen for symptoms. The goal was to better understand mental health needs in this group.

This study looked at how mindfulness-based cognitive therapy (MBCT) changes brain activity in 61 adults with PTSD. Participants received either MBCT or a mind-body comparison therapy, and researchers used fMRI scans to measure brain connectivity before and after treatment. The go…

This completed study looked at whether mothers' anxiety and depression levels are linked to sleep patterns in children aged 0-36 months who were hospitalized in a general pediatrics clinic. Researchers measured mothers' anxiety and depression using standard questionnaires and com…

This study looked at how the brain develops over time in young teenage girls who have hurt themselves on purpose (non-suicidal self-injury). Researchers used interviews, brain scans (MRI), and thinking tests to understand the condition better. A total of 168 girls took part, incl…

This study looked at 105 adults getting a wisdom tooth removed under anesthesia. Researchers tested whether getting information verbally, through traditional materials, or from an AI source changed how anxious patients felt. The goal was to see which method helps people feel calm…