New study: can targeted radiation save thinking skills in patients with multiple brain tumors?
NCT ID NCT02953717
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two types of radiation for people with 11 to 20 brain tumors that spread from other cancers. One group got Gamma Knife radiosurgery, which targets each tumor precisely. The other got whole brain radiation, which treats the entire brain. The goal was to see which approach better protects memory and thinking. 81 patients took part, and researchers measured cognitive decline three months after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Gamma Knife radiosurgery and whole brain radiation therapy
- What this could lead to
- If Gamma Knife causes fewer memory and thinking problems, it could become the preferred treatment for patients with multiple brain metastases.
- What could go wrong
- This is a small, completed study with only 81 participants. Results may not apply to all patients, and Gamma Knife may not control tumors as well as whole brain radiation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gamma Knife Center Tilburg, Elisabeth-TweeSteden Hospital
Tilburg, North Brabant, 5022 GC, Netherlands
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