Spinal fluid DNA test could personalize brain cancer therapy

NCT ID NCT07689721

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study explores whether analyzing tumor DNA in cerebrospinal fluid can help doctors make better treatment decisions for people with malignant brain tumors or brain metastases from lung or breast cancer. Participants undergo a standard spinal tap or fluid collection, and the fluid is tested with a special DNA assay alongside usual methods. The goal is to see if this test improves how well the disease is controlled in the central nervous system over six months, while also monitoring safety. The results could lead to more personalized and timely treatments for these serious conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Belay Summit CSF ctDNA assay (diagnostic test)
What this could lead to
If successful, this approach could help doctors tailor treatments more precisely for brain cancer patients, potentially improving survival and reducing unnecessary therapies.
What could go wrong
This is an early-stage, single-center study with a small sample size. The test may not reliably predict outcomes, and treatment decisions are not standardized, limiting generalizability.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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