Drugs and therapy together: a new hope for anxiety, depression, and more?

NCT ID NCT06993662

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disorder, schizophrenia, and personality disorders. About 107 participants aged 18-65 will receive the combined treatment in a private practice setting. The study measures changes in thinking, mood, and overall recovery over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

combination of anxiety and depression medications (anxiolytics and antidepressants) plus cognitive behavioral therapy

What this could lead to

If it works, this could point toward a more effective way to manage multiple mental health conditions by combining standard drugs with talk therapy.

What could go wrong

This is a very early Phase 1 study with no control group, so results may not be reliable. The wide range of conditions and lack of blinding make it hard to know if the combination is truly better than either treatment alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder bipolar disorder Depression depressive disorder obsessive-compulsive disorder personality disorder Personality Disorders post-traumatic stress disorder psychotic disorder Psychotic Disorders schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Private practice of Dr. S. Rakitzi and Dr. P. Georgila ILISION 34 15771 ATHENS GREECE

    Athens, 15771, Greece