CBD drops for anxiety: small study shows promise?

NCT ID NCT02548559

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a cannabidiol (CBD) solution placed under the tongue could help adults with moderate to severe anxiety. 46 participants took either full-spectrum CBD, single-compound CBD, or a placebo three times daily for four weeks, alongside their usual treatments. Researchers tracked anxiety levels, mood, sleep, and quality of life to see if CBD offered extra relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabidiol (CBD)

What this could lead to

If it works, this could point toward a natural option for easing anxiety symptoms.

What could go wrong

This is a small, early-phase trial with only 46 participants. Results may not apply to everyone, and CBD can cause side effects like drowsiness or digestive issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McLean Hospital Brain Imaging Center

    Belmont, Massachusetts, 02478-9106, United States