Could mushroom supplements soothe anxiety in young women?

NCT ID NCT06406946

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study investigates whether taking lion's mane mushroom or a blend of lion's mane and reishi mushroom for 28 days can improve wellbeing in women aged 18-26 who feel stressed or anxious. Participants are randomly assigned to receive one of the mushroom supplements or a placebo, and their anxiety, stress, fatigue, and self-esteem are measured through questionnaires. The goal is to see if these natural supplements offer a safe way to support mental health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lion's mane mushroom and a blend of lion's mane and reishi mushroom
What this could lead to
If it works, this could point toward a natural supplement option for easing anxiety and stress in young women.
What could go wrong
This is a small, early-stage trial with only 84 participants, and the effects may be modest or no better than placebo. Dietary supplements are not regulated as strictly as drugs.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brain, Performance and Nutrition Research Centre, Northumbria University

    Newcastle upon Tyne, Tyne and Wear, NE1 8ST, United Kingdom

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