Beyond breathing: could an asthma drug lift emotional burdens for patients and partners?
NCT ID NCT04680611
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This study looks at how mepolizumab (Nucala), a treatment for severe eosinophilic asthma, impacts emotions and mental well-being in patients and their partners. Researchers will track changes in feelings like anxiety, depression, and stress using questionnaires and interviews. The goal is to understand the broader psychological effects of this therapy beyond just lung function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mepolizumab (Nucala)
- What this could lead to
- If successful, this could reveal how a biologic treatment for severe asthma improves emotional health and quality of life for patients and their partners.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all asthma patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Respiratory Medicine, Aberdeen Royal Infirmary
Aberdeen, Grampian, AB25 2ZN, United Kingdom
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Glasgow Gartnavel General Hospital
Glasgow, G12 0YN, United Kingdom
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Hull University Teaching Hospitals NHS Trust
Hull, Yorkshire, HU16 5JQ, United Kingdom
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Judit Varkonyi-Sepp
Southampton, Hampshire, SO166YD, United Kingdom
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Pinderfields Hospital
Wakefield, Yorkshire, WF1 4DG, United Kingdom
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Portsmouth Hospitals NHS Trust
Portsmouth, United Kingdom
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