Longer diazepam use may curb alcohol relapse

NCT ID NCT02242955

First seen Apr 24, 2026 · Last updated Jun 22, 2026 · Updated 9 times

Summary

This study tested whether giving people with alcohol dependence a one-month course of diazepam (40 mg per day) after detoxification could reduce the chance of relapsing into drinking within the next three months. The standard detoxification treatment is usually about one week. The idea was that longer treatment might ease lingering anxiety that often leads to relapse. The study enrolled 26 adults who had already started detoxification.

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Contacts and locations

Locations

  • Department of Addiction Medicine

    Lille, 59037, France

  • Outpatient Addiction Center "CSAPA - Le Pari"

    Lille, 59037, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

diazepam

What this could lead to

If it works, this could point toward a longer treatment approach to help prevent early alcohol relapse after detoxification.

What could go wrong

This is a very small, early-phase study with only 26 participants, so results may not apply broadly. The extended diazepam use also carries risks like dependence and side effects.

Conditions

The condition(s) this trial relates to.

alcohol abuse anxiety disorder Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.