Wisdom tooth study probes brain chemicals for clues to pain and anxiety
NCT ID NCT07644065
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 40 people having both wisdom teeth removed, two weeks apart. Researchers measured two natural chemicals in the blood—serotonin and kynurenic acid—before and after surgery to see if they relate to pain and anxiety. The goal was to better understand how these chemicals influence recovery, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ibuprofen, Gabapentin, Placebo
- What this could lead to
- If successful, this could help explain how the body's natural chemicals affect pain and anxiety after surgery, potentially guiding better pain management.
- What could go wrong
- This is a small, early-stage observational study with only 40 participants. The findings may not apply to other types of surgery or pain conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dental Medicine
Plovdiv, Plovdiv, 4002, Bulgaria
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