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Could an 8-Day therapy course help teens overcome panic and agoraphobia?

NCT ID NCT00576719

Disease control Sponsor: Boston University Charles River Campus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether an intensive, 8-day form of cognitive behavioral therapy (CBT) can help adolescents with panic disorder and agoraphobia. The therapy includes 15-20 hours of one-on-one sessions focused on changing anxious thoughts and gradually facing feared situations. Some teens receive the therapy alone, while others have their parents involved. The goal is to see if this short but intense approach reduces panic attacks, fear, and avoidance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
intensive cognitive behavioral therapy (CBT) with exposure, delivered over 8 days with 15-20 hours of therapist contact
What this could lead to
If successful, this could provide a fast, effective treatment option for teens with panic disorder and agoraphobia, reducing symptoms and improving daily functioning.
What could go wrong
This is a small, early-stage study with 63 participants, so results may not apply to all teens. The intensive format may be hard to fit into regular care, and long-term benefits are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

63 people

The number who actually took part.

Start date

Mar 2005

Finished

Mar 2011

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meets DSM-IV criteria for principal diagnosis of PD or PDA prior to treatment * Adolescent must be accompanied by at least one parent or caregiver * If on medication, there must be a 1-month stabilization period for benzodiazepines or 3-month stabilization period for SSRIs or tricyclics prior to study entry Exclusion Criteria: * Positive diagnosis of schizophrenia, pervasive developmental disorder, organic brain syndrome, mental retardation, or current suicidal ideation * Unavailability of at least one parent or caregiver * Refusal of parent to accept random assignment to treatment condition * Refusal of parent or adolescent to accept stabilization of medication * Adolescent with parent who has any condition that would limit ability to understand treatment

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Conditions

The condition(s) this trial relates to.

agoraphobia panic disorder panic disorder with agoraphobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Agoraphobia Panic disorder

Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02215, United States

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