Anxiety disorder

This completed study tested a program called RISE (Resiliency in Stressful Experiences) for young men ages 18-35 leaving state prisons in Florida. The program combines trauma counseling with practical help like housing and job support. Researchers measured whether participants ha…

This trial tests whether a 12-week telerehabilitation program—combining aerobic walking and progressive relaxation exercises—can improve blood sugar control, stress, anxiety, and physical function in adults with type-2 diabetes, both with and without a prior COVID-19 infection. P…

This trial tests whether different intensities of breathing exercises (inspiratory muscle training) can improve diaphragm function, thinking, sleep, and mood in young adults aged 18-25 who have low muscle mass. Participants will be randomly assigned to high-intensity, moderate-in…

This early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…

This trial tests whether a procedure called renal denervation — which uses ultrasound to calm overactive nerves around the kidneys — can lower blood pressure and reduce anxiety in people with uncontrolled hypertension. Sixty adults aged 30 to 70 with high blood pressure and eleva…

This pilot study is testing whether adults with serious mental health issues like psychosis, anxiety, or depression can receive hospital-level care in their own homes. Researchers will see how many people are eligible and willing to try this approach. The goal is to offer a safe,…

This study tests whether a combination of a special omega-3 supplement (LIPINOVA®) and a home-based exercise and education program can improve quality of life for people with lingering post-COVID symptoms. About 146 adults aged 18–70 who have had symptoms for more than 12 weeks w…

This trial tests whether a structured family support program helps relatives of critically ill patients in intensive care units (ICUs). The program includes a specialist nurse who supports families from admission through discharge and follow-up, plus better communication between …

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tested whether a 3-year physical activity program could help prevent colon cancer from coming back in 889 patients who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. Participants were randomly assigned to either the exercise program plus…

This study tested whether giving people with alcohol dependence a one-month course of diazepam (40 mg per day) after detoxification could reduce the chance of relapsing into drinking within the next three months. The standard detoxification treatment is usually about one week. Th…

This study tested a program called Positive Minds-Strong Bodies Enhanced (PMSB-E) in 427 older adults from racial, ethnic, and linguistic minority groups who had depression, anxiety, and some mobility issues. The program combined mental health support with physical exercises to h…

This study tested a 12-month telephone-based nurse care program for 805 adults with depression and signs of opioid use disorder. Participants were randomly assigned to receive nurse support or usual care. The goal was to see if the program could improve treatment for opioid use a…

This study tested whether adding mental health care (like therapy and education) to standard job support helps people on sick leave due to anxiety or depression return to work sooner. Over 600 participants in Denmark were randomly assigned to one of two programs or usual care. Th…

This trial tests whether a group prenatal care model that includes social services can improve maternal mental health and reduce preterm birth compared to standard individual care with added services. Pregnant women eligible for Medi-Cal in central California are randomly assigne…

Researchers are testing a school-based program that screens adolescents for anxiety, depression, and other mental health concerns, then offers stepped support. Students at eight schools in Spain complete regular mental health questionnaires. Based on their results, they receive d…

This trial tests whether short, equipment-free exercise sessions in the classroom can ease anxiety, depression, and stress while boosting physical activity in medical students. Around 105 students will be split into groups receiving either two, one, or no exercise sessions per we…

This study tested an online mentoring program for transgender and gender minority youth aged 14-18. The program paired each teen with an adult transgender mentor for seven 90-minute group sessions focused on building social and emotional skills. The goal was to prevent problems l…

This study follows up on 217 children who took part in a cognitive behavioral therapy program for anxiety and depression 5 years earlier. Researchers want to see if the program helped prevent these conditions from developing or worsening over time. The children, now teenagers, wi…

This study tested an online program called PROCARE-I+ designed to prevent anxiety and depression in teenagers who are at high risk. Thirty adolescents with early symptoms took part in the program, which included extra modules tailored to their needs. Results showed improvements i…

This study tested an online psychological program designed to prevent depression in people with atrial fibrillation (AF), a common heart rhythm problem. The program combined phone or video sessions with online modules and exercises over 4-12 weeks. The trial included 28 adults wi…

This study tested whether promoting a free web and mobile tool called StopBlues could reduce suicides and suicide attempts in the general population. Over 100,000 adults in 42 French communities took part, with some communities actively promoting the tool and others not. The goal…

This study tested whether a single 3-hour group therapy session based on Acceptance and Commitment Therapy (ACT) could prevent mental health disorders in 120 women recently displaced by war in Ukraine. The women had mild to moderate symptoms of anxiety or depression. The goal was…

This study tested a device called Cereset Research that plays tones in response to a person's brainwaves, aiming to reduce stress and improve sleep. 94 stressed healthcare workers used the device for several sessions and were followed for a year. The goal was to see if the device…

Researchers are testing a cognitive behavioral therapy program designed for autistic teens who have anxiety, depression, or both. The therapy focuses on exposure and behavioral activation, with adjustments for autism. Teens and their caregivers take part together. The trial compa…

Researchers are testing whether inhaling a low dose of xenon gas can ease anxiety before laser vision correction. The trial enrolls 140 people who score high on stress and anxiety tests and are scheduled for ReLEx SMILE eye surgery. Participants receive either xenon or a standard…

This trial tests whether drinking lavender herbal tea twice daily for nine days around each menstrual cycle can reduce the emotional and physical symptoms of premenstrual syndrome (PMS), such as anxiety, depression, stress, and pain. Sixty women with PMS will be randomly assigned…

Researchers are testing whether the 4-7-8 breathing technique can reduce anxiety, ease symptom burden, and improve sleep quality in people receiving chemotherapy. The trial enrolls 64 adults undergoing their third treatment cycle, splitting them into a group that practices the br…

Researchers are testing whether giving children a popit toy or a stress ball during inhaled medication can reduce anxiety, fear, and distress. The trial includes children aged 4 to 6 who come to a pediatric emergency unit with a respiratory condition needing nebulizer or inhaler …

Researchers are testing a stepped mental health program for adolescents in Pakistani public schools. The program starts with teacher-led support for emotional distress. Students who do not improve move to a CBT-based guided self-help app. The study checks whether this approach is…

Researchers are testing whether a horticultural therapy program can reduce anxiety and improve quality of life in older adults. The trial enrolls 56 volunteers who take part in gardening activities. Participants complete standard questionnaires about anxiety and well-being before…

This study looked at whether mandala art therapy (a structured coloring activity) can lower anxiety and increase comfort in people who received a kidney transplant. Eighty adult first-time kidney transplant recipients took part. The goal was to see if this simple, non-drug approa…

This study tested whether watching calming VR videos or squeezing a stress ball could reduce pain, anxiety, and improve satisfaction during insulin injections in older adults (65+) with type 2 diabetes. 90 participants were split into three groups: VR, stress ball, or usual care.…

Electromyography (EMG) and nerve conduction studies (NCS) check how nerves and muscles work, and many patients find them painful or stressful. Researchers are testing whether letting adults choose and listen to their own music during these tests lowers anxiety and pain compared w…

Researchers are testing a four-week acceptance and commitment therapy program for parents of children with complex medical conditions. The trial enrolls 24 parents who attend two-hour weekly sessions covering stress, values, mindfulness, and goal-setting. The study measures chang…

Researchers at Oregon State University are testing whether a brief, Spanish-language group program can reduce anxiety in Latino/a adults. The program teaches neuroscience-informed cognitive behavioral therapy over three weekly 90-minute sessions and asks participants to track the…

This study tests whether combining progressive muscle relaxation and guided imagery can lower stress, anxiety, and depression in people with stable coronary artery disease. Forty adults will be split into two groups: one gets eight sessions of these mind-body techniques over four…

Many people who move to a new country face depression, anxiety, stress, and trouble adjusting. This pilot study tests whether EMDR, a psychotherapy that uses guided eye movements to process distressing memories, can help when adapted for migration-related experiences. First-gener…

Researchers are testing whether a home-based program led by community health workers can reduce depression in older adults living in a low-resource district of Lima, Peru. The program, called VIDACTIVA, combines problem-solving exercises and physical activation over eight home se…

Intravitreal injections deliver medicine directly into the eye and are usually quick, but many patients feel anxious before and during the procedure. Researchers are testing whether playing classical music during the injection lowers anxiety and pain compared with no music. The t…

This study will test whether watching a liquid-gel or sand hourglass during blood collection can reduce pain, fear, and anxiety in children aged 5 to 10. About 120 children will be randomly assigned to use one type of hourglass or no hourglass. The goal is to find a simple, non-d…

This study tests whether using a virtual reality headset showing nature scenes with relaxing music can reduce pain and anxiety during dressing changes for pressure sores. Sixty-two adults with pressure sores will be randomly assigned to either receive VR during dressing or standa…

This study looked at whether structured play activities could reduce anxiety in children aged 4-10 receiving chemotherapy and their parents. 62 children and their parents took part in play sessions during chemo. Anxiety levels were measured before and after play. The goal is to s…

Researchers test whether an 8-session mindfulness-based stress reduction program can lower anxiety and work-related burnout and improve job satisfaction among midwives. Midwives at a Turkish hospital join either the program or a control group. The program runs online twice a week…

Researchers are testing whether a structured Enhanced Recovery After Surgery (ERAS) program improves recovery for people having their first coronary artery bypass graft. The program bundles 31 care steps before, during, and after surgery, including patient education, nutrition su…

Researchers are testing whether virtual reality glasses that show nature scenes with nature sounds can reduce pain and anxiety in women after a cesarean section. The trial enrolls 80 women who had spinal anesthesia and a healthy pregnancy, assigning half to use the VR glasses for…

Researchers at Atlas University are comparing three daily breathing practices, mindfulness breathing, box breathing, and Nadi Shodhana pranayama, in 48 healthy adults aged 18 to 40. Participants practice one technique at home for six weeks after learning it in person. The trial m…

Researchers are comparing two 9-week group classes for veterans who have a history of mild traumatic brain injury and post-traumatic stress disorder. One class teaches mindfulness, meditation, and yoga; the other teaches how the brain works and recovers after injury. The study me…

This study will test whether watching a short educational video or having a standard talk with a doctor is better at reducing anxiety and stress in women scheduled for a planned cesarean delivery. 140 women will be randomly assigned to one of the two groups. Their anxiety levels …

This study will test whether foot reflexology—a type of foot massage—can help women aged 18-45 with migraines feel less pain, anxiety, and fear of movement. Twenty women will either receive 10 foot massage sessions over 5 weeks or no massage. Researchers will measure changes in h…

Researchers at the University of Guadalajara are testing whether a short acceptance and commitment therapy (ACT) program can reduce anxiety in medical students. The program runs four in-person group sessions that teach students to accept difficult thoughts and feelings, step back…

This trial tests whether acupressure, a traditional therapy that presses on specific body points, can reduce pain and anxiety in women who have just had a cesarean delivery. Sixty postpartum women will receive either acupressure or a sham version, along with standard medical care…

People with type 2 diabetes often face higher rates of anxiety and depression than the general public. Researchers at Dasman Diabetes Institute are testing whether six weeks of guided breath awareness, practiced inside a pyramid-shaped structure, can reduce those symptoms. The pi…

This study tests a group cognitive-behavioral therapy (CBT) program designed to help young adults who struggle with uncertainty. The program includes techniques like cognitive restructuring and exposure to uncertain situations, and it considers how a person's social environment a…

Researchers at MIT are testing whether a smartwatch that vibrates in time with your heartbeat can improve interoceptive awareness, the ability to sense what is happening inside your body. The study enrolls 29 people with high alexithymia scores, a trait linked to difficulty ident…

This study tests a mindfulness program (called GEM) delivered through an app and weekly group video calls. It aims to see if young adults (ages 18-24) who have faced early life hardships find the program helpful and easy to use. The study also checks if the program reduces sympto…

This trial tests whether teaching mothers how to perform aspiration care for their children in the intensive care unit can lower their anxiety and hopelessness. Researchers will compare two teaching methods: a video and a picture booklet. The study includes mothers whose children…

This trial tests whether a quilling exercise, a paper craft activity, can reduce fear and anxiety in children aged 9-12 who are about to undergo cardiac catheterization and angiography. Half an hour before the procedure, children in the intervention group will spend 15-20 minutes…

This trial tests whether letting children play video games or paint a mask during nebulizer treatment reduces their anxiety and improves how well they cooperate. The study includes children aged 7 to 12 who are receiving their first nebulizer treatment in the hospital. Researcher…

This study looks at whether mindfulness meditation can help first-generation college students feel less anxious or depressed and stay in school. About 53 students will be randomly assigned to either mindfulness meditation or a general mental health education group. Researchers wi…

Researchers are testing whether chewing mint-flavored sugar-free gum during childbirth can reduce pain and anxiety in first-time mothers. The trial includes 106 pregnant women at term with no complications, who will chew the gum for at least 20 minutes at different stages of labo…

Researchers are testing whether psilocybin, the active compound in magic mushrooms, can safely help people with Parkinson's disease who also struggle with depression or anxiety. In this pilot study, 12 participants receive two oral doses of psilocybin with psychological support. …

This study tested a new cognitive behavioral skills program (CBI) delivered in the metaverse for people with depression and anxiety. 306 participants were split into three groups: one using virtual reality, one using a flat-screen device, and a waitlist group. The program taught …

This trial tests whether a digital cognitive behavioral therapy (CBT) app called Daylight can reduce anxiety and improve health behaviors in adults who have had a heart event, such as a heart attack or stroke, and also experience significant anxiety. Participants will either use …

This study tests whether adding a group therapy called Kiesler Circle Training (KCT) to standard cognitive behavioral therapy (CBT) helps people with depression or anxiety improve their interpersonal skills. About 156 participants will receive either CBT alone or CBT plus KCT. Th…

This study tests whether giving a small amount of the sedative midazolam during anesthesia can lower the risk of delirium (sudden confusion) and anxiety in older adults after surgery. About 612 patients aged 65-85 having non-heart, non-brain surgery will be randomly assigned to r…

This study tested a new anxiety program designed for autistic youth ages 7 to 17. The program was delivered in community care centers to make it more accessible. Researchers wanted to see if it was practical and helpful for reducing anxiety symptoms. The study involved 32 partici…

This study tests whether using a virtual reality headset during labor can help reduce pain and anxiety and make the childbirth experience more satisfying. About 92 women in Taiwan will be randomly assigned to either use VR with calming nature scenes and music or receive standard …

This study looked at whether teaching patients about pain before a planned hysterectomy (removal of the uterus) could help lower their anxiety, stress, and pain after surgery. 62 adults took part and received either standard care or extra education about pain. The goal was to see…

Researchers at Brigham and Women's Hospital are testing whether automated motivational messages or coach support can improve engagement with SilverCloud, a digital mental health intervention for depression and anxiety. The trial enrolls adults with clinically significant symptoms…

This study tests whether chamomile or valerian extracts can reduce dental anxiety in healthy children aged 6 to 10 who need a tooth pulled. Kids are randomly given one of the herbal extracts or a placebo before the procedure. Researchers measure anxiety using child-friendly emoji…

This trial tests whether aromatherapy with rose oil or a massage using that oil can reduce pain, anxiety, and discomfort in women after a cesarean delivery. About 90 first-time mothers will be randomly assigned to receive one of these treatments or a placebo. The goal is to see i…

This study tests whether a 6-week group class on nonviolent communication (NVC) can improve mental well-being in parents of primary-school children. About 172 parents with mild to severe anxiety or depression symptoms will be randomly assigned to take the class right away or wait…

This trial tests whether watching short family videos or virtual reality nature scenes can reduce anxiety, agitation, and pain in adults staying in intensive care. Researchers will randomly assign 72 participants to one of three groups: family videos, family videos plus VR nature…

This trial investigates whether a structured educational program led by nurses can reduce anxiety and improve outcomes for adults undergoing their first heart surgery. Participants are randomly assigned to receive either the nurse-led program or usual care. The program covers pre…

This trial tests whether virtual reality-based breathing yoga can reduce pain and anxiety in adults before chest tube removal after cardiac surgery. Participants are randomly assigned to either watch breathing yoga videos through VR glasses for 15-20 minutes before the procedure,…

This study looked at whether an antidepressant, physical therapy, or a combination of both can help people with chronic low back pain who also struggle with negative feelings. About 308 adults aged 18-75 with pain lasting over 6 months took part. The goal was to see if these trea…

This pilot study will test whether a weighted blanket can help reduce anxiety and pain in people recovering from total knee replacement surgery. Thirty adults scheduled for knee replacement at NYU Langone will be randomly assigned to receive either a weighted blanket or a regular…

This trial tests whether a six-week program of mandala coloring—two 20-30 minute sessions per week—can improve psychological resilience among midwives working in hospital delivery rooms. These professionals face high stress from heavy workloads, shift work, and traumatic events, …

This study tested whether using a virtual reality headset showing calming scenery for 20-30 minutes could lower anxiety in parents whose children were in the hospital. 485 parents participated, and their anxiety levels were measured and compared to standard care without any tech-…

This study tests a mobile health system (smartwatch and app) combined with a week-long cycling event to help veterans reduce stress and PTSD symptoms. Thirty-six veterans will use the system for two months and participate in the cycling challenge. The goal is to see if this appro…

This trial tests whether looking at a ceiling-mounted curtain with a nature scene during a thyroid biopsy can lower pain, anxiety, and fear. About 100 adults scheduled for an ultrasound-guided fine-needle aspiration biopsy will be randomly assigned to either watch the curtain dur…

This trial tests whether acupressure applied to the Yintang point—a spot on the forehead—can reduce pain, anxiety, and improve satisfaction during childbirth. About 104 first-time mothers in active labor will receive either Yintang acupressure or a light touch at a non-therapeuti…

This trial tests whether an online therapy platform, BetterHelp, can reduce symptoms of moderate to severe depression and anxiety. Adults in the US with elevated scores on standard anxiety or depression scales will either get access to the platform for 16 weeks or be in a control…

This study tested whether an 8-week mindfulness-based stress reduction program could lower depression, anxiety, stress, and hopelessness in parents of children with autism. 96 parents took part in weekly 60-minute group sessions. The goal is to see if this simple, non-drug approa…

This study tests whether listening to live ukulele music for 30 minutes, one day after a cesarean delivery, can help reduce pain-related distress and anxiety while improving overall comfort. First-time mothers who had a C-section under spinal anesthesia will be randomly assigned …

This study looks at whether watching an animated film or reading a storybook can lower fear and anxiety in children aged 7 to 12 who have just been diagnosed with type 1 diabetes. About 64 children will take part, and their anxiety levels will be measured using special child-frie…

This study tested a program called ENCODE designed to help family caregivers of people with dementia manage stress and communicate better about pain. 452 caregivers were randomly assigned to either the ENCODE program or friendly video calls. The goal was to see if the program imp…

This trial tests whether combining 40-Hz binaural beat music with rhythmic light stimulation can reduce anxiety and psychological distress in adults with schizophrenia or schizoaffective disorder. Participants receive 20-minute sessions three times a week for 12 weeks, either wit…

This trial explores whether an internet-based cognitive behavioral therapy (CBT) program, combined with COPD education, can improve mental health, disease knowledge, and quality of life in adults with chronic obstructive pulmonary disease (COPD). Participants complete the 8-10 we…

This study tests whether guided mindfulness exercises delivered through a virtual reality (VR) headset can help older adults with symptoms of anxiety and depression. Participants in Ecuador will be randomly assigned to either VR mindfulness sessions or a simple phone check-in. Th…

This trial explores whether two different internet-delivered programs can help pregnant women reduce stress, anxiety, and depression. One program teaches cognitive-behavioral stress management skills, while the other is a supportive group discussion. Researchers will measure chan…

This trial tests whether a single 20-minute virtual reality session featuring calming nature scenes can reduce fear and anxiety in adults scheduled for bariatric (weight-loss) surgery. Participants will view 360° footage of forests, seas, and landscapes in their hospital room sho…

This trial tests whether a robotic pet or a video can reduce pain, fear, and anxiety in children aged 5-10 during a blood draw (venipuncture). Children are randomly assigned to interact with a robotic pet, watch an animal video, or receive routine care during the procedure. Resea…

This trial tests whether a 15-minute mixed reality session, featuring underwater scenes and guided relaxation, can reduce pain intensity in adults with chronic musculoskeletal pain. Participants are randomly assigned to either the active therapy or a sham control, both delivered …

This trial tests whether Emotional Freedom Technique (EFT), a therapy that combines tapping on acupressure points with focused thoughts, can reduce the emotional impact of a traumatic childbirth. Women who had a vaginal birth and reported high levels of childbirth-related distres…

This trial tests whether music therapy can reduce pain, anxiety, and stress in people undergoing hemodialysis for kidney failure. Participants in the intervention group listen to music for 30 minutes during their dialysis sessions, while a control group receives standard care. Re…

This trial tests whether listening to personalized music during cataract surgery can reduce anxiety and pain. About 100 patients having surgery under local anesthesia will either receive standard care or also listen to their preferred instrumental music (60-100 beats per minute) …

This trial tests whether a group-based psychological treatment for insomnia, adapted for people with depression, anxiety, or PTSD, can improve sleep and reduce psychiatric symptoms. Participants receive either the adjusted CBT-i program or usual care. The study measures changes i…

This study tests whether a 20-minute foot reflexology session can reduce pain, anxiety, nausea, and vomiting in adults after laparoscopic gallbladder removal. Participants receive the foot massage in addition to standard postoperative care, and their symptoms are measured before …

This study tests a small vibrating device held near the skin during needle sticks (like IVs or blood draws) to see if it lowers pain and anxiety. About 1,100 children and adults will take part. Researchers will watch and ask about discomfort to see if the buzz helps people feel c…

This study tested whether wearing virtual reality glasses during a common kidney stone treatment (ESWL) can lower patients' pain, anxiety, and improve comfort. Seventy adults undergoing the procedure for the first time took part. Researchers measured pain, anxiety, and comfort le…

This trial investigates whether a 20-minute virtual reality nature scene or the Benson Relaxation Technique can lower anxiety and increase happiness in adults who have recently had bariatric surgery. Participants are randomly assigned to one of two groups or a control group, and …

This study tested whether playing white or pink noise through headphones before and during a colonoscopy can lower patients' pain and anxiety. 135 adults were randomly assigned to listen to white noise, pink noise, or standard care alone. Researchers measured anxiety and pain usi…

This study tests whether a virtual reality (VR) mindfulness app can reduce anxiety before surgery and acute pain after surgery. Adults scheduled for surgery will use the VR headset for up to 25 minutes, and researchers will measure changes in anxiety and pain scores, as well as u…

This study looks at whether adding sensory and cognitive activities—like listening to music, gentle touch, or brain exercises—to standard ICU care can help adults recover faster after heart surgery. About 125 patients will be randomly assigned to one of four groups to see which a…

This trial tests whether an online psychiatric nursing program based on the Tidal Model can improve psychological resilience and self-compassion in adults diagnosed with anxiety disorder. Participants are randomly assigned to either receive eight one-on-one online nursing session…

This study tested whether a structured education session led by a nurse could lower anxiety and improve quality of life in 188 adults having their first shock wave lithotripsy for kidney stones. The education covered what to expect during the procedure, pain management, and recov…

This trial tests whether using real-world props, like a kayak paddle or sitting in an actual kayak, can lower anxiety during a virtual reality (VR) kayaking game in adolescents with mild to moderate intellectual disabilities. Participants will be randomly assigned to play the VR …

This trial tests whether listening to preferred music or squeezing a stress ball during cataract surgery can reduce patients' pain and anxiety. About 240 adults having their first cataract surgery will be assigned to one of these two simple, drug-free techniques or to standard ca…

This study tested whether a computerized training program that targets emotional reactions can help relieve obsessive thoughts and compulsive behaviors in people with OCD. Five adults with OCD completed 14 training sessions over three weeks. The goal was to see if this approach c…

This study tests whether watching a virtual reality (VR) video of an electroconvulsive therapy (ECT) session can reduce anxiety and improve knowledge about the procedure. About 64 adults about to have ECT for the first time will be randomly assigned to either a VR education sessi…

This trial is testing a program called TEAMSS, designed to help fifth graders with elevated anxiety transition more smoothly to middle school. The program includes reading materials, a school tour, group sessions, parent meetings, and teacher consultations. The goal is to see if …

This trial asks whether letting mothers use their personal cellphones during a planned C-section under spinal anesthesia can lower anxiety and stress and improve satisfaction. About 82 low-risk pregnant women will be randomly assigned to either use their phones freely during surg…

This trial tests whether watching a 30-40 minute augmented-reality animation that shows a child's journey through surgery can reduce anxiety in children aged 3-12 before adenotonsillectomy. Half the children will watch the animation before surgery, while the other half receives s…

This pilot trial tests whether pediatric primary care providers can effectively deliver a brief intervention called the Anxiety Action Plan (AxAP) to help children aged 6-17 with elevated anxiety symptoms. Providers receive training and coaching to administer the intervention, wh…

This trial tests whether a daily synbiotic supplement, combining probiotics and a prebiotic fiber, can ease common perimenopause and menopause symptoms like poor sleep, anxiety, and brain fog. Women aged 44–55 experiencing these symptoms will take either the active supplement or …

This study tests if using a stress ball can reduce pain, anxiety, and changes in heart rate during chest tube removal after open heart surgery. About 46 adults who have one chest tube after surgery will be split into two groups: one will squeeze a stress ball during the procedure…

This study tests whether haptotherapy, a gentle touch-based therapy, can reduce anxiety and improve bonding in pregnant women who have had a previous abortion. Eighty women between 28 and 32 weeks of pregnancy will receive five 45-minute group sessions. Researchers will measure a…

This study explores whether listening to music after a cesarean section can help first-time mothers feel less pain and anxiety, and improve their breastfeeding success. Participants will be divided into groups, with one group listening to music and the other receiving standard ca…

This trial asks whether wearing a virtual reality (VR) headset before and during short hand surgeries can help reduce pain and anxiety. Adults undergoing elective hand surgery with local anesthesia and sedation will use the VR headset as a distraction. Researchers will measure se…

This study tests whether weekly live harp music sessions can reduce behavioral symptoms like agitation and anxiety in nursing home residents with moderate-to-severe dementia. Participants in memory care units will listen to a harp therapist play during the late afternoon, a time …

This study tests a smartphone app called Orbi, which uses cognitive behavioural therapy (CBT) to help people with long-term physical conditions cope with depression and anxiety. 60 participants will either use the app plus usual charity support, or charity support alone, then swi…

This study tests whether using virtual reality glasses or doing breathing exercises during chemotherapy can help reduce anxiety in breast cancer patients. Participants will be divided into three groups: one using VR glasses, one doing guided breathing exercises, and one receiving…

This trial tests whether a smartphone app called MindBoba, which uses problem-solving therapy techniques, can help Chinese Americans reduce stress and anxiety. Participants will be randomly assigned to use MindBoba, a standard cognitive-behavioral therapy app, or receive no app. …

This study follows 140 people with obstructive defecation syndrome (ODS) — a condition that causes straining and difficulty passing stool — who are scheduled for surgery. Researchers will measure depression and anxiety using standard questionnaires before and after the procedure,…

This trial tests whether a mindfulness-based neurofeedback program can help racial and ethnic minority college students reduce performance anxiety and improve academic performance. Participants practice mindfulness meditation while a device monitors their brain activity and provi…

This study tests whether using a virtual reality headset during PICC line placement can reduce anxiety and pain in cancer patients. About 120 adults will be randomly assigned to either receive VR plus standard care or standard care alone. The goal is to see if this non-drug appro…

This study tests whether wearing virtual reality glasses during a cystoscopy—a procedure to look inside the bladder—can reduce pain and anxiety. Half of the participants will use VR while the other half receives standard care. The trial aims to see if VR can make the experience m…

This study tests whether wearing virtual reality goggles that show calming nature scenes with music can reduce pain, anxiety, and changes in heart rate and blood pressure during urodynamics, a procedure that checks how well the bladder works. Half of the participants will wear th…

This trial tests whether an augmented reality (AR) app-based cognitive behavioral therapy (CBT) program can help children aged 6 to 12 who are undergoing chemotherapy for cancer cope with treatment-related distress and improve their quality of life. Participants are randomly assi…

This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can reduce psychological and existential distress in people with advanced, terminal illness. Participants receive rTMS sessions while on a palliative care unit, and researchers measure changes in depress…

This trial tests whether adding a ChatGPT-powered educational tool to standard instructions helps first-time colonoscopy patients achieve better bowel cleansing and feel less anxious before the procedure. Adults undergoing their first colonoscopy are randomly assigned to receive …

This study tests whether a four-week mindfulness program can reduce symptoms of depression, anxiety, and stress in college students in Guangzhou, China. Participants are randomly assigned to either the mindfulness training or a health education control group. The study also looks…

This trial tests whether watching an entertaining video through virtual reality glasses or on a tablet can reduce pain, anxiety, and fear in children aged 7 to 12 during intravenous (IV) cannulation in an emergency department. Children are randomly assigned to one of three groups…

This trial compares two simple educational tools—an animated video and a brochure—against routine care to see which best lowers anxiety and fear in children aged 7 to 10 who need an echocardiogram. All participants have a congenital heart condition and are scheduled for a follow-…

This pilot trial tests whether adding microcurrent neurofeedback (MCN) to standard residential treatment helps adults with substance use disorder more than standard care alone. MCN uses scalp sensors to deliver barely perceptible electrical pulses tailored to each person's brain …

This trial tests whether distraction techniques—like drawing, reading a story, watching a cartoon, or using a toy nebulizer and mask—can lower fear and anxiety in children aged 3 to 6 during inhalation therapy for respiratory infections. Children are randomly assigned to one of t…

This study tests two medications, dexmedetomidine and tramadol, given before hemorrhoid surgery to see which one better reduces anxiety and pain. Ninety adults will receive one of the drugs or a placebo before spinal anesthesia. Researchers will measure anxiety levels and pain sc…

This trial tests whether a 4-week progressive muscle relaxation (PMR) program can reduce psychological stress and improve bowling speed and accuracy in male cricket medium-fast bowlers aged 18-25. Participants are assigned to either PMR sessions before warm-ups or standard traini…

This trial tests whether using an immersive virtual reality headset during the first postoperative orthopedic dressing change can reduce anxiety and pain in children and adolescents aged 6 to 18. Participants are randomly assigned to either wear the VR headset during the procedur…

This trial compares two diets—low-FODMAP and lactose- and gluten-free—in adults with irritable bowel syndrome (IBS). Each participant tries both diets for four weeks, with a one-week break in between, to see which one better reduces gut symptoms and improves mental health. The go…

This study tested whether a 12-session parenting group therapy, called the Connecting and Reflecting Experience (CARE) program, is helpful and doable for new parents struggling with postpartum depression or anxiety. Seventeen parents of babies aged 3 to 12 months took part. The g…

This trial tests whether coloring pre-drawn mandala patterns for at least 30 minutes each day can lower anxiety and depression in adults awaiting open-heart surgery. About 69 first-time heart surgery patients will be randomly assigned to either the coloring activity or usual care…

This study tests whether giving family members of ICU patients a QR code that links to an educational video can improve their understanding of the ICU and reduce their anxiety. Participants are randomly assigned to receive either standard verbal information or the same informatio…

This pilot study tests a new approach for misophonia, a condition where common sounds like chewing or breathing cause extreme distress. Sixty adults with moderate to severe misophonia will learn emotion regulation skills and receive one of two types of brain stimulation (rTMS) ov…

This study tests whether watching an animated educational video before laparoscopic tubal ligation reduces anxiety and pain more than standard verbal counseling. Eighty women are split into two groups: one receives routine verbal information, the other watches a video. Researcher…

This trial investigates whether wearing AI-powered active noise-cancelling headphones during rotational atherectomy — a heart procedure that generates loud drilling noise — can reduce patient anxiety and improve heart rate stability. One hundred adults with severe coronary artery…

This study is testing a behavioral therapy called 'Being Brave' to help reduce anxiety in autistic children aged 3 to 6. The therapy involves 16 weekly sessions with parents and children, using visual aids and practice exercises. Researchers will also look at biological markers t…

This study tested a counseling program called the Friendship Bench for 106 teens aged 13-18 who have HIV and feel depressed or anxious. The program aims to improve their mood and help them stay engaged in their HIV care. Researchers measured how well the program worked by looking…

This study tests whether using a stress ball or watching a short aquarium video with music can reduce fear, anxiety, and pain in children aged 6 to 12 who need an enema for constipation or bloating in the emergency department. Children are randomly assigned to one of the two dist…

This early-phase trial tests a new brain stimulation target for people with depression plus at least one other psychiatric disorder, such as anxiety, OCD, or PTSD. The treatment uses a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation …

This study tests whether a new type of group therapy, called Group Cognitive Evolutionary Therapy, can help reduce symptoms of depression and anxiety. Sixty-four adults with mild to severe depression will either receive two full days of therapy or be placed on a waiting list. Res…

This study looked at whether using artificial intelligence to teach first-time mothers about planned cesarean sections could lower their fear and anxiety and improve their comfort after birth. 75 pregnant women between 18 and 35 took part. The results help show if AI can be a sim…

This pilot study tests whether a brief psychological program called Problem Management Plus (PM+) can help reduce anxiety and depression symptoms in people held in Dutch remand prisons. The program, developed by the World Health Organization, teaches problem-solving, stress manag…

This study tests whether a 10-week storytelling (narrative therapy) program can reduce anxiety and depression in middle school students living in refugee camps in northern Palestine. About 120 students aged 12-15 with moderate-to-severe symptoms took part. The program uses cultur…

This study tested whether listening to Baroque music for 30 minutes could reduce anxiety in 18 adults with major depressive disorder. Participants listened to a specially chosen set of Baroque pieces, and their anxiety levels were measured before and after. The idea is that the m…

This study tests whether a one-day Acceptance and Commitment Therapy (ACT) workshop can improve psychological flexibility and well-being in university students who have moderate to severe anxiety or depression. Participants are randomly assigned to either attend the workshop or j…

This study tests whether writing about imagined future scenarios (worst-case, best-case, or neutral) can reduce social anxiety symptoms. 270 adults with elevated social anxiety will complete three online writing sessions over three weeks. Researchers will measure changes in anxie…

This study tests whether watching short telenovela-style videos can reduce anxiety and boost confidence in African-American and Hispanic family caregivers of hospice patients. 62 caregivers will either watch the videos during telehealth visits or receive usual hospice care. The g…

This trial tests whether a brief online group therapy called EMDR Flash can help adults who survived the 2023 Kahramanmaraş earthquakes in Türkiye. Participants receive two 60-90 minute group sessions via Zoom and are compared to a waitlist group. The study measures changes in PT…

This study tested a 5-month early time-restricted eating plan (eating only between 7 AM and 3 PM) in 100 highly trained young male judo athletes. Researchers measured changes in body composition, muscle damage markers, and psychological factors like anxiety and self-confidence. T…

This pilot study tested a six-session culturally adapted cognitive behavioral therapy (Ca-CBT) for depression and anxiety in 50 people living with HIV in Pakistan. The therapy was delivered by trained HIV health workers and included culturally relevant stories and materials. The …

This study tested whether adding dog-assisted therapy to usual care helps teens aged 12-18 with mental health issues like anxiety, depression, and emotional dysregulation. 70 teens in a day hospital were randomly assigned to either get dog therapy plus usual care or usual care al…

This pilot study tested whether a non-invasive device that uses magnetic pulses to stimulate the brain (rTMS) could safely help cancer survivors with depression and anxiety. Twenty-four adults who had been treated for any type of cancer and still had major depression received eit…

This trial investigates whether a double-reading animated film, watched by both children and their parents before surgery, can reduce anxiety in children aged 3 to 7. The film uses avatars to walk the child through their hospital journey, from room to operating room. Researchers …

This study tested whether repeating positive affirmations during a routine pregnancy test (Non-Stress Test) can lower pain, anxiety, fear, and stress. 90 pregnant women participated, with some using affirmations and others receiving standard care. The goal is to see if this simpl…

This study tested whether daily gummies containing L-theanine and lion's mane mushroom extract could reduce stress, anxiety, and improve sleep in university students. 67 students aged 18-25 took either the gummies or no supplement for 8 weeks. The goal was to see if this natural …

This study looked at whether touch-massage can reduce anxiety in people with blood disorders (like leukemia or lymphoma) who are hospitalized in a sterile, isolated room. Sixty-two patients received three massage sessions, and researchers measured their anxiety levels before and …

This study tested whether Swedish massage with lavender or chamomile oils can help reduce pain, fear, and anxiety during labor. 90 pregnant women were split into three groups: one got massage with chamomile oil, one with lavender oil, and one with plain carrier oil. Researchers m…

This study tests two short behavioral therapies delivered over video calls for adults with chronic orofacial (jaw or face) muscle pain and insomnia. One therapy focuses on sleep habits and routines; the other uses jaw relaxation and breathing exercises. The goal is to see which a…

This pilot study tested whether adding a 16-week meditation program to standard cardiac rehabilitation helps people with coronary artery disease feel less stressed and anxious. Forty participants were split into two groups: one did meditation plus rehab, the other did rehab alone…

This study looked at whether teaching cancer patients about their portable chemotherapy pump (elastomeric pump) can make them feel more comfortable and less anxious. 70 adults receiving 5-FU treatment were split into two groups: one got extra education and a booklet, the other go…

This study tested whether full-spectrum CBD oil can help with anxiety and depression in people with Parkinson's disease. Twenty-seven participants took one of three daily doses (30, 60, or 300 mg) for two months. Researchers measured changes in anxiety and depression scores, alon…

This study tested whether watching telenovela-style educational videos can help family caregivers of hospice patients feel more confident and less anxious. 59 caregivers participated over 8 weeks. The approach used weekly video lessons during regular hospice visits.

This study tested whether a gentle ear stimulation technique could reduce stress and anxiety in healthcare workers during the COVID-19 pandemic. 62 workers were randomly assigned to receive the stimulation or be placed on a waiting list. The goal was to see if this simple, non-dr…

This study tested a virtual reality app called StoryTelling Medicine (STM) to see if it could reduce anxiety in children aged 8–13 before elective surgery. The app guides kids through hospital settings in a fun, interactive way. Researchers measured anxiety, heart rate, and stres…

This study looked at whether music therapy can lower anxiety in women with early-stage breast cancer during chemotherapy. Twenty-seven patients took part, with some receiving music therapy sessions while others did not. Researchers measured anxiety levels before and after each ch…

This study looked at whether using a virtual reality hypnosis headset during a frozen embryo transfer is practical and can help lower anxiety. Fifty women undergoing IVF used the headset during the procedure. The main goal was to see if the headset could be used without technical…

This study tested whether wearing a virtual reality headset during heart device implantation (like pacemakers) could reduce patients' anxiety and pain. 111 adults were randomly assigned to use VR or standard care. The goal was to see if distraction through VR lowers stress and di…

This study tested an online guided self-help program called EMPOWER for medical professionals with mild depression or anxiety. The program teaches problem-solving and acceptance skills through videos and stories. 161 participants were randomly assigned to the program or a control…

This study tested whether listening to music during a daily cleaning procedure can reduce pain in children aged 6 months to 15 years in a pediatric intensive care unit. Each child experienced the cleaning twice—once with music and once without—and pain was measured using a standa…

This study tested whether wearing virtual reality goggles during the needle stick for dialysis can lower pain and anxiety. Fifty adults on hemodialysis were randomly assigned to either watch VR content during the procedure or receive usual care. The results will show if a simple,…

This study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…

This study tested a 6-week mindful self-compassion program for homeless women with PTSD and substance use. The program includes meditation, group discussions, and home practices. Researchers compared the program to usual care in 202 women living in a residential drug treatment fa…

This study looked at whether having dim light (50-80 lux) in the delivery room can help reduce pain and anxiety during labor. 120 pregnant women in active labor were randomly assigned to either a dimly lit room or standard lighting. Researchers measured pain and anxiety levels at…

This study tested whether squeezing a stress ball during an ultrasound-guided biopsy can reduce pain and anxiety. 79 adults were randomly assigned to either use a stress ball or receive standard care alone. Researchers measured pain, anxiety levels, and vital signs before and aft…

This study tested a brief, community-based psychological program called Problem Management Plus to see if it can reduce depression, anxiety, and distress. Over 1,200 adults with mild to moderate symptoms took part. The program focuses on practical problem-solving skills in just f…

This study tested whether aromatherapy with essential oils can reduce anxiety in adults before elective upper limb surgery. 289 participants were randomly assigned to either receive aromatherapy or not. The goal was to see if the scent helped people feel calmer in the operating r…

This study looked at whether multi-family therapy (therapy with several families together) can help teenagers who refuse to go to school because of anxiety. 74 teens aged 12-18 who had been out of school for at least 2 weeks took part. The researchers measured anxiety and school …

This study tested a 3-week program that helps cancer patients identify their personal strengths (like hobbies, social support, or personal qualities) and use them to cope better. 32 adults with different cancers took part in card-sorting sessions, phone calls, and home exercises.…

This study tested whether a 6-session educational program could help people receiving electroconvulsive therapy (ECT) feel less stigma and anxiety about their mental health treatment. Sixty adult inpatients with conditions like depression or bipolar disorder took part. Those who …

This study tested whether Acceptance and Commitment Therapy (ACT) can improve the well-being of parents caring for children with autism. Thirty parents in Saudi Arabia took part in online ACT sessions over five weeks. Researchers measured changes in stigma, mindfulness, and stres…

This study tested whether wearing virtual reality goggles showing relaxing nature scenes and music during IUD insertion could reduce pain and anxiety. 70 women were randomly assigned to either VR or standard care. Researchers measured pain, anxiety, comfort, and vital signs. The …

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This study tested whether listening to nature sounds while walking after gallbladder surgery could reduce anxiety, pain, and stress. Seventy adults who had laparoscopic cholecystectomy took part. Patients walked 50 meters while hearing nature sounds, then returned to bed. Their a…

This study tested whether wearing a virtual reality mask during blood draws and allergy skin tests helps children aged 7 to 13 feel less pain and anxiety. About 300 kids from two hospitals took part. The goal was to see if distracting them with VR makes these procedures easier to…

This study tested a digital program to support the mental health of doctors during the COVID-19 pandemic. 293 physicians from Penn Medicine took part. The program included text messages, resource support, and peer groups. Researchers measured changes in well-being, depression, an…

This study tested whether using bandages printed with cartoon characters helps children feel less fear, stress, and pain during burn dressing changes. 42 children aged 6-11 with second-degree burns were randomly assigned to get either cartoon or plain bandages. The goal was to se…

This study tested whether a short behavioral program called Acceptance and Commitment Therapy (ACT) could reduce pain and improve function in veterans at risk for persistent pain after knee replacement. 402 veterans were randomly assigned to ACT or an attention control group. Res…

This study tested a personalized internet-based program (WebTIPS) to help children ages 1-12 feel less anxious before surgery and recover more smoothly. Over 1,200 parent-child pairs took part, with some using the tailored program and others receiving standard online information.…

This study tested a version of cognitive behavioral therapy (CBT) that was adapted to fit the cultural background of Canadians of South Asian origin. Researchers worked with 146 adults who had depression or anxiety to see if this tailored therapy could help reduce their symptoms.…

This study tested a 4-week program called COPE (Coping Options for Parent Empowerment) for parents of teenagers in Spain. The program teaches emotional regulation and positive parenting skills in group sessions. Researchers measured changes in parents' anxiety, depression, stress…

This study tested whether wearing virtual reality glasses during a routine postpartum uterine tone assessment could lower anxiety and pain while increasing comfort. 146 women within 24 hours of giving birth participated. Researchers measured pain with a visual scale and anxiety w…

This study looked at whether using white noise or squeezing a stress ball during a routine fetal heart rate test (NST) can lower anxiety and fear in pregnant women who are scheduled for a planned C-section. 168 women were split into four groups: white noise, stress ball, both, or…

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) could help young adults aged 18-39 who have cancer or desmoid tumors manage anxiety and depression. The program teaches skills like stress management, goal setting, and positive thinking.…

This study tested whether letting patients watch their own ACL reconstruction surgery live on a screen helps them feel less afraid of moving after the operation. 65 adults having ACL surgery under spinal anesthesia either watched the procedure or received standard care. The goal …

This study tested a brief virtual therapy called MAPP (Mindful Adaptive Practice in Pregnancy) to help pregnant women manage COVID-19-related anxiety. 69 women participated, comparing MAPP to usual care. The goal was to see if the therapy is feasible and acceptable, not yet to pr…

This study tested whether using virtual reality (VR) before a first-time heart catheterization could lower anxiety more than just standard education. 180 adults were split into two groups: one got VR plus education, the other only education. Anxiety was measured with a standard q…

This study tested whether structured educational sessions could reduce tokophobia—an intense fear of pregnancy and childbirth—in 50 pregnant women in Egypt. The program included five sessions covering causes, coping strategies, and lifestyle tips. Researchers measured changes in …

This study tested a new, non-invasive treatment for major depression called transcranial photobiomodulation (tPBM), which uses near-infrared light on the scalp. Fifty adults with depression received either real light therapy or a sham treatment three times a week for six weeks. T…

This study tested a mindfulness-based program (including breathing exercises and meditation) in 39 Generation Z nursing students during their clinical internship. The goal was to see if it could improve mental health and reduce anxiety, depression, and stress compared to usual ca…

This study looked at whether a short virtual reality mindfulness session could help patients feel less anxious and stressed after heart surgery. 34 adults who had heart bypass or valve repair took part. One group did a 15-minute VR mindfulness exercise, while the other group rece…

This study tested a program that combines counseling (behavioral activation) with medication adjustments to reduce depression and anxiety in adults aged 60 and older who were scheduled for hip or knee replacement surgery. 116 participants were randomly assigned to receive the pro…

This study looked at whether smelling lavender essential oil for 20 minutes before orthopedic surgery could lower anxiety, stress, and depression. 128 adults in Jordan took part, with half inhaling lavender oil and the other half receiving usual care. Results showed that the lave…

This study tested whether using virtual reality (VR) can help reduce pain and anxiety in people recovering from heart surgery, specifically when chest tubes are removed. 200 adults who had just had heart surgery were given either VR or nitrous oxide (laughing gas) during the proc…

This study tested whether using virtual reality hypnosis before chemotherapy infusions could lower anxiety in men with metastatic prostate cancer. Fifty-three patients were randomly assigned to either receive the VR hypnosis session or standard care before each docetaxel infusion…

This study tested a mobile app called PCYCARE in 120 first-time pregnant women in their third trimester. The app provides educational modules and guided relaxation sessions over 21 days. Researchers measured changes in anxiety, sleep quality, and childbirth preparedness compared …

This study tested a stress management program for nursing students aged 18-25 who had mild to moderate depression. The program taught cognitive-behavioral skills to handle stress. Students who took part reported lower levels of depression, anxiety, and stress compared to those wh…

This study tested a 5-week online group program called Rare Group Problem Management Plus (PM+) for parents of children with rare diseases. The program teaches stress management and problem-solving skills to help reduce anxiety, depression, and distress. Eight parents participate…

This study tested a program where parents and children prepare together before surgery to see if it lowers children's anxiety when they get anesthesia. Fifty children aged 5 to 12 having planned surgery took part. The program involved parents being present and prepared for the op…

This study tested a 9-week online mindfulness program for teens aged 12-17 with anxiety or depression. Half of the teens also had a parent or caregiver join the program. Researchers wanted to see if adding a caregiver improved the teen's symptoms. The study was very small (32 par…

This study tested a brief, self-guided internet-based cognitive behavioral therapy (iCBT) program designed for university students, researchers, and staff. The program includes four weekly modules to help manage stress and anxiety. Researchers enrolled 35 participants to see if t…

This study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…

This study tested whether listening to positive affirmations along with classical music during a cesarean section could lower anxiety and improve breastfeeding. 99 women were split into three groups: one listened to affirmations with music, one listened to music only, and one had…

This study tested whether a trained nurse using 'hypnotic communication'—a calm, supportive way of talking—could help men feel less anxious and experience less pain during a prostate biopsy. One hundred men were randomly assigned to receive either standard care or standard care p…

This small study tested a structured mindfulness program for adults with both substance use disorder and anxiety. Three participants completed the program to see if it was feasible and could help reduce stress and anxiety. The study focused on emotional awareness and coping skill…

This study tested whether wearing a virtual reality headset showing a nature video could reduce pain and anxiety in 90 adults undergoing coronary angiography, a heart procedure where patients are awake. One group watched the VR video during the procedure, while the other received…

This study tested whether using virtual reality (VR) glasses for 30 minutes each evening could improve sleep quality, reduce anxiety, and stabilize vital signs in intensive care patients with COPD. Fifty patients were split into two groups: one received VR sessions for a week, th…

This study tested whether listening to music during radionuclide treatment helps prostate cancer patients feel less anxious and distressed. Sixty men were split into two groups: one listened to their choice of instrumental music through headphones during treatment, while the othe…

This study tested whether a program called MindUP could help lower depression, anxiety, and stress in orphan teenagers in Pakistan. 61 boys aged 11-16 living in orphanages took part. Some did the MindUP program, which teaches mindfulness and emotional skills, while others did the…

This study tested whether progressive muscle relaxation (PMR) — a technique where you tense and then relax different muscle groups — could help nursing students feel less depressed, anxious, and stressed. Over 100 students were split into two groups; one group practiced PMR three…

This study tested a mindfulness-based psychoeducation program for 66 nurses working in intensive care, oncology, and emergency units. The goal was to see if the program could reduce burnout, improve clinical decision-making, and ease existential anxiety. Researchers measured chan…

This study looked at whether taking omega-3 supplements (like fish oil) could help with anxiety, depression, and vitamin D levels in college students aged 18-27. Over 100 students took either a placebo, a low dose, or a high dose of omega-3s daily for 90 days. Researchers measure…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study tested whether hypnosis can lower pain and anxiety during an ultrasound-guided liver biopsy. 70 adults were randomly assigned to receive either hypnosis or standard care during the procedure. Researchers measured pain and anxiety levels to see if hypnosis made the expe…

This study tested whether having a therapy dog present during dental treatment helps children aged 4 to 12 who are afraid of the dentist behave better and feel calmer. Twenty children each had two dental visits—one without a dog and one with a trained therapy dog. Researchers com…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study looked at whether therapeutic touch — a gentle, non-medical hands-on technique — can help first-time mothers feel less pain and anxiety during labour. Eighty women were split into two groups: one received therapeutic touch, the other standard care. Researchers measured…

This study tested a new online program for people with gut-brain interaction disorders (DGBI) who also have anxiety or depression. 27 adults tried self-guided online sessions and gave feedback through interviews and questionnaires. The goal was to see if the program is easy to us…

This study tested whether using virtual reality (VR) during tooth extractions can lower anxiety in adults. 119 people having at least two teeth pulled under local anesthesia were randomly assigned to either use VR or not. Researchers measured anxiety before and during the procedu…

This study tested a daily microalgae extract (Tetrasol) in 62 healthy adults with mild stomach issues to see if it helps gut health, anxiety, and immune function. Participants took the supplement for 4 weeks, and researchers measured symptoms, stress levels, and safety through bl…

This study tested a behavioral program called IMPROVE to help college students who drink heavily and feel anxious. The program teaches skills to handle anxiety and uncertainty without turning to alcohol. Forty students took part, and researchers checked if the program was easy to…

This study tested whether listening to music with AI-generated verbal guidance that uses Eastern imagery can reduce anxiety and improve mood in Chinese university students. 123 participants were randomly assigned to music with AI guidance, standard relaxation guidance, or music a…

This study looked at whether a structured counseling session over the phone before cataract surgery could lower patients' anxiety and improve their recovery. 128 adults scheduled for cataract surgery took part. Half received the extra phone counseling, while the other half got st…

This study tested whether a single 60-minute session of a videogame called 'ACTing Minds' could improve mental health in 302 adults with mild to moderate depression, anxiety, or stress. The game is based on Acceptance and Commitment Therapy (ACT) and aims to increase psychologica…

This study looked at whether a short session of bodyweight exercises combined with group motivation, breathing, and stretching could lower stress hormones and improve mood in healthy young adults aged 18-25. 84 participants were split into three groups: exercise plus motivation, …

This study tested whether different types of sounds (natural, city, broadband, or silence) can help improve mood, stress, and anxiety in people with fibromyalgia. 72 adults with fibromyalgia listened to each sound for 20 minutes during four weekly visits. Researchers measured cha…

This study tested whether group music therapy can improve emotional well-being, anxiety, and social connectedness in university students. 120 students in urban China were randomly assigned to active music-making, guided music listening, or a waitlist. Both therapy formats were de…

This study tested a 12-week mobile phone program of daily reflection and meditation exercises for children with cancer and their families. The goal was to see if the program is practical and helpful for improving mental well-being and reducing anxiety and depression. Forty partic…

This study tested a collaborative care model for people with depression in general practice. 389 Danish-speaking adults with depression were randomly assigned to either collaborative care (involving a care manager and stepped treatments like therapy and medication) or standard co…

This study tested whether a guided mindfulness meditation program, practiced during dialysis sessions, could reduce anxiety and improve spiritual well-being in people with chronic kidney disease. Fifty-eight adults on hemodialysis were randomly assigned to either the meditation g…

This study tested whether two types of gentle exercise—stretching or traditional pregnancy exercises—could improve sleep quality in pregnant women during their third trimester. Sixty women with sleep troubles took part in guided sessions twice a week for three weeks. The goal was…

This study tested several non-drug methods—like a textured plastic device called ShotBlocker, a vibrating ice pack (Buzzy), and a skin-tapping technique—to reduce pain from injections in children aged 4 to 6. 120 kids in a pediatric emergency department took part. The goal was to…

This study tested two types of online therapy for anxiety and depression in 2477 adults. Participants received either a cognitive behavioral treatment or a psychodynamic treatment, delivered over 8 or 16 weeks, with or without a support forum. The goal was to see which combinatio…

This study tested an app called EMPOWER-ED that provides education and tools to help veterans reduce or stop taking benzodiazepines (like Xanax or Ativan). Long-term use of these drugs can lead to dependence and other risks. The study enrolled 170 veterans who had been taking ben…

This study tested whether a procedure called a stellate ganglion block (SGB), given with standard medication, could improve thinking and memory in people with Alzheimer's disease. Forty participants were randomly assigned to receive either SGB plus standard drugs or standard drug…

This study tested whether an AI voice coach called Lumen can help adults with mild-to-moderate depression or anxiety. 200 participants were randomly assigned to receive problem-solving training from Lumen, a human coach, or a waitlist. The goal was to see if the AI coach could im…

This study tested a simple web-based platform called Adhere.ly to help therapists and their clients with therapy homework. 79 adults with anxiety or depression took part. The goal was to see if using the tool improved symptoms and quality of life compared to standard therapy alon…

This study looked at whether Emotional Freedom Technique (EFT), a method that involves tapping on specific body points, can help postmenopausal women feel less pain and anxiety before a probe curettage (a uterine biopsy). 132 women participated, and researchers measured their pai…

This study looked at whether showing cartoons or playing music during tooth extractions can lower pain and anxiety in children aged 6 to 12. Sixty kids were randomly assigned to watch cartoons, listen to music, or receive standard care. Researchers measured heart rate, oxygen lev…

This study looked at whether chewing gum (with or without sugar) can help children aged 7 to 12 feel less pain and fear during a blood draw. A total of 144 kids were randomly assigned to chew sugared gum, sugar-free gum, or no gum at all. Researchers measured pain, fear, and cryi…

This study looked at whether doing Zumba for 10 weeks could help reduce anxiety and depression in healthy adults aged 40 to 65. Forty people were split into two groups: one did Zumba three times a week, and the other continued their normal routine. Researchers measured mood befor…

This study tested a therapist-guided online program called AMOR for pregnant women and new mothers with ADHD. 31 participants listened to podcasts and attended online group sessions. The goal was to see if the program was easy to use and helpful for managing ADHD, stress, anxiety…

This study tested whether using virtual reality (VR) during a trans-vaginal ultrasound could help women with endometriosis feel less anxious and experience less pain. 155 women were randomly assigned to either use VR for relaxation during the exam or receive standard care. Resear…

This study tested an 8-week mindfulness-based psychoeducation program in 50 adults diagnosed with anxiety disorders. Half took the program, half did not. Researchers measured changes in perceived stress, intolerance of uncertainty, and cognitive flexibility. The goal was to see i…

This study looked at whether listening to music for a week before colon cancer surgery can lower anxiety. 116 adults scheduled for surgery were asked to listen to music three times a day. Their anxiety levels were compared to a group that did not have a music routine. The goal is…

This study tested a manual acupressure technique called Energy Resonance by Cutaneous Stimulation (RESC) to see if it could lower anxiety in 57 women about to undergo a breast macrobiopsy. Participants received a RESC session before the procedure, and their anxiety was measured u…

This study tested whether doing progressive relaxation exercises after emergency general surgery could help with pain, anxiety, and vital signs like heart rate and breathing. Seventy adults were randomly assigned to either do these exercises at specific times after surgery or rec…

This study looked at whether two sessions of hypnosis could lower anxiety in pregnant women with preterm premature rupture of membranes (PPROM). 60 women took part, with some receiving hypnosis and others standard care. The goal was to see if hypnosis helps reduce anxiety and imp…

This study tested whether using virtual reality (VR) in the waiting room could reduce anxiety in 156 adults about to undergo a heart catheterization. Participants used VR while waiting for their procedure, and researchers measured their stress levels using heart rate monitors and…

This study tested whether medical hypnosis can reduce anxiety and pain in patients undergoing electroneuromyography (ENMG), a nerve test that can be uncomfortable. Six anxious adults were enrolled and received either hypnosis or standard care. Researchers measured pain and anxiet…

This study tested whether aesthetic therapy sessions (like skincare or makeup) could reduce anxiety and improve quality of life for patients with acute leukemia or those who had a stem cell transplant. These patients are isolated in a protected hospital area for at least 28 days.…

This study tested an internet-based therapy program for adults still struggling with depression or anxiety after the COVID-19 pandemic. 24 participants in Sweden completed 8 weeks of online therapy with a therapist's support. The goal was to see if this approach could reduce ling…

This study tested whether qigong relaxation exercises can lower anxiety and depression in adults hospitalized for depression. 70 patients participated in a randomized controlled trial. The goal was to see if adding qigong to standard care improves mood and reduces anxiety symptom…

This study tested whether listening to music during wound dressing changes can help reduce pain and anxiety in people with venous leg ulcers. 97 patients were split into three groups: one listened to Turkish instrumental music, one to Western music without lyrics, and one had no …

This study tested whether playing with an interactive toy or a robot during nebulized inhalation treatment reduces anxiety and fear in children aged 4-10 in the pediatric emergency department. 72 children were randomly assigned to use an interactive doll, a robot, or standard car…

This study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…

This study tested a culturally adapted internet-based cognitive behavioral therapy (iCBT) program for Arabic-speaking refugee and migrant youth aged 15–29 with mild to moderate mental health problems like depression, anxiety, and insomnia. 125 participants were randomly assigned …

This study tested a 4-week movement program called Dance-Walk in 117 adults seeking mental health support. Participants either started the program right away or waited. The goal was to see if combining dance and walking could improve body awareness, energy, and reduce stress, anx…

This study looked at whether two types of talk therapy—cognitive behavioral therapy (CBT) and relaxation training—could improve mood and thinking in people with relapsing-remitting multiple sclerosis. 140 participants with mild to moderate disability were randomly assigned to one…

This study tested a program called Mood Lifters for college students. 125 undergraduates attended 14 weekly virtual meetings to learn mental health strategies. The goal was to see if this low-cost, peer-led approach could reduce symptoms of depression, anxiety, and stress. Resear…

This study tested a program called PRISM that teaches stress management, goal-setting, and coping skills to adolescents and young adults (ages 12-24) with advanced cancer. Researchers wanted to see if it could improve quality of life and reduce anxiety and depression. The program…

This study tested whether using virtual reality (VR) goggles during a blood draw could reduce pain, anxiety, and emotional distress in school-age children. 86 children were randomly assigned to either active VR (where they could control the experience) or passive VR (just watchin…

This study tested whether online group singing classes could help new mothers with postnatal depression feel better. 37 mothers with babies up to 9 months old joined 6 weekly online singing sessions. The goal was to see if singing together could reduce depression symptoms, especi…

This study tested whether virtual reality (VR) sessions can help reduce anxiety and depression in people aged 12 to 25 who do not want to take medication. Forty participants completed five weekly VR sessions focused on relaxation, coping skills, and healthy habits. Researchers me…

This study tested whether using a stress ball during an elective cesarean section can reduce anxiety and pain and help with breastfeeding. 109 pregnant women participated. Half used a stress ball for 15 minutes during surgery, while the other half did not. Researchers measured an…

This study tested whether listening to relaxing instrumental music during prostate surgery helps reduce anxiety and pain afterward. 135 men having a specific type of prostate surgery were randomly assigned to either listen to music or receive standard care. Researchers measured a…

This study tested a single-session program for children ages 7 to 17 with anxiety and their parents. The program teaches kids how to manage anxious thoughts and feelings, and shows parents how to support them. Researchers wanted to see if this quick help could reduce anxiety symp…

This study tested whether listening to music through headphones during cataract surgery could reduce anxiety and prevent high blood pressure. Over 300 patients took part, with some listening to music and others wearing silent headphones. The goal was to see if a simple, non-drug …

This study tested whether a simple mandala coloring activity could reduce anxiety, fatigue, and improve sleep quality in people aged 65 and older living in nursing homes. Over 8 weeks, participants colored mandala patterns for 1-2 hours each week. The study measured changes using…

This study tested a new web app that uses cognitive behavioral therapy (CBT) to help people with depression and anxiety. Researchers wanted to see if the app was easy to use and helpful. 50 adults from low- and middle-income countries took part. The goal was to see if this digita…

This study tested whether virtual reality (VR) exposure therapy could reduce anxiety in people with epilepsy who worry about their seizures. Fourteen participants were split into two groups: one received VR therapy using 360-degree videos of social or public settings, and the oth…

This study tested whether providing digital mental health resources (like apps and websites) to teens with anxiety in primary care could improve their understanding of anxiety and confidence to manage it. 365 teens from underserved communities participated. The goal was to see if…

This study tested a new type of talk therapy that helps people aged 50 to 90 learn to change how they think about upsetting memories and feelings. The goal was to reduce the risk of suicide after a hospital stay for suicidal thoughts or a suicide attempt. 107 participants took pa…

This study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble reintegrating into civilian life. The workshop taught skills like emotional control, problem solving, and attention to improve daily function and reduce anger. It was designed as a non-stigma…

This study looked at whether music therapy sessions could help people with depression feel better and become more resilient. 84 participants aged 8 to 70 with depression took part in weekly music therapy or wellness concerts for three months. Researchers measured changes in depre…

This study tested whether electronic distractions like music, virtual reality, or TV can reduce discomfort in ICU patients. Sixty awake, non-delirious adults tried each device for 15 minutes. Researchers measured changes in pain, anxiety, thirst, shortness of breath, and insomnia…

This study tested whether using virtual reality (VR) exposure therapy could prevent anxiety, depression, and PTSD in people recovering from a lung transplant in the ICU. 62 adults on the lung transplant waiting list participated. They used a VR headset to gradually get used to st…

This study tested whether watching 360° virtual reality movies can reduce fear and anxiety in cancer patients about to start radiation therapy. 292 adults with breast, lung, prostate, head and neck cancer, or brain tumors participated. Patients watched a VR movie and then filled …

This study tested whether a colorful undersea-themed cover for the exam table could lower fear and anxiety in children aged 3 to 12 during their first ECG. 80 children participated, with half using the special cover. The goal was to see if this simple, non-medical change could ma…

This study tested whether coloring mandalas (circular patterns) could improve mood and quality of life for 51 adults hospitalized with depression and anxiety. Participants completed 8 guided coloring sessions over 3 weeks. Researchers measured changes in depression, anxiety, stre…

This study tested whether taking part in art activities (like painting, music, or dance) can improve mental well-being. 382 people with mental health issues such as anxiety, depression, or emotional disorders were randomly assigned to either an art program or a waitlist. The stud…

This study tests whether shining low-level laser or LED light on specific acupoints on the hand can help people relax and improve sleep and anxiety. Researchers will measure heart rate and energy levels in 60 healthy volunteers before and after light therapy. The goal is to see i…

This study tested two online programs—cognitive behavioral therapy (CBT) and mindfulness—to help adults cope with the distress caused by tinnitus (ringing in the ears). 67 participants were randomly assigned to one of the two treatments or a waiting list. The goal was to see if t…

This study tested whether listening to slow-tempo music through noise-cancelling headphones twice a day could help older adults in the ICU avoid delirium—a state of confusion linked to longer hospital stays and lasting cognitive problems. Researchers enrolled 160 critically ill p…

This completed study tested a one-session, nurse-led intervention called the Riddikulus Nursing Intervention to reduce anxiety in university students. 36 students with moderate anxiety were randomly assigned to receive the intervention or not. The approach helped students reframe…

This study tested whether using a hand fan for 10 minutes daily over six weeks could reduce shortness of breath, anxiety, and depression in people with COPD. Fifty-nine patients from a hospital in Turkey took part, with half using the fan and half receiving standard care. The goa…

This study tested whether using augmented virtual reality (AVR) during chemotherapy can help reduce pain, stress, and anxiety while boosting self-confidence. 150 adult cancer patients in the West Bank were split into two groups: one received standard care, and the other used AVR …

This study looked at whether listening to relaxing classical music could help women feel less pain and anxiety after a cesarean delivery. 110 first-time mothers who had a C-section took part. Starting 24 hours after birth, the music group listened to 15 minutes of classical music…

This study tested whether a self-hypnosis smartphone app called Hypnotidoo could improve attention and reduce anxiety in children aged 7 to 12 with ADHD who were already taking methylphenidate. The app offers short, screenless audio sessions with stories and breathing exercises. …

This study tested three types of medicinal cannabis oil (with different levels of THC and CBD) against a placebo in 91 cancer patients. The goal was to see which oil, if any, helps with pain, nausea, anxiety, and sleep problems. Each patient tried multiple oils and a placebo in a…

This study looked at whether telling patients they don't need to fast before cataract surgery could lower their anxiety. 126 adults having their first cataract surgery under topical anesthesia were surveyed. The goal was to see if a non-fasting recommendation could make the exper…

This study tested whether using a peanut-shaped ball between the knees during early labor can lower anxiety and pain in first-time mothers. 163 women were randomly assigned to use the ball or not. Researchers measured anxiety and pain levels using standard scales. The goal is to …

This study tested whether a 6-week group dance fitness class could lower stress and improve mood in women aged 30 to 60. Forty-six women from Louisiana State University either joined the dance classes or continued their usual routine. Researchers measured stress through saliva sa…

This study tested a new program called Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT) for veterans with anxiety disorders. It involved 48 veterans and their family members to see if adding family support to standard therapy was acceptable and helpful. The main goal was t…

This study tested whether a colorful, interactive toy called the Storytelling Caterpillar could help children aged 3 to 6 feel less pain and anxiety during a blood draw. 140 children were randomly assigned to either use the toy during the procedure or receive standard care. Resea…

This study looked at whether showing patients a dynamic video before a prostate biopsy could lower their pain and anxiety compared to just verbal instructions or static images. 223 men aged 50-80 with elevated PSA levels participated. Pain was measured with a Visual Analog Scale …

This study tested whether daily omega-3 supplements (fish oil) can help reduce stress, anxiety, depression, and improve memory and sleep in 64 Saudi adults who reported high stress. Participants took either omega-3 or a placebo for three months. Those taking omega-3 reported lowe…

This study looked at 40 people having both wisdom teeth removed, two weeks apart. Researchers measured two natural chemicals in the blood—serotonin and kynurenic acid—before and after surgery to see if they relate to pain and anxiety. The goal was to better understand how these c…

Researchers at Hacettepe University are studying people who had surgery for a massive rotator cuff tear. They want to see how the brain's signals to shoulder muscles, shoulder function, and psychological resilience relate to each other. Participants complete shoulder and mood que…

This study looked at whether people with alcohol dependence or a history of early life stress have more trouble learning to feel calm after a scary event. Researchers used brain scans, mild electric shocks, and genetic tests to understand these differences. The goal was to learn …

This study explores the connection between anxiety and frailty in people aged 65 and older who are about to have hip replacement surgery. Researchers will measure anxiety and frailty using standard questionnaires before the operation. The goal is to understand how these factors r…

This study investigates how the brain's emotion network works by recording brain activity directly from the surface of the brain in people with epilepsy who are already undergoing surgery for seizure monitoring. Participants watch short video clips designed to trigger emotions li…

This study tests whether a training program for parents of children who have had a febrile convulsion (a seizure caused by fever) can lower parental anxiety and increase their knowledge about the condition. About 66 parents of children aged 6 months to 5 years will be randomly as…

This study follows people treated for anal cancer with radiotherapy to see how their sexual quality of life changes over time. Participants complete questionnaires during treatment, three months later, and two years after diagnosis. The goal is to understand the long-term impact …

Researchers at Jacobs University Bremen are running a three-phase study to understand how environmentally friendly behaviors relate to eco-anxiety, well-being, and loneliness. About 1,684 adults complete surveys about their food choices, consumption habits, and feelings of social…

This study surveys Indonesian sports science undergraduates to understand how self-esteem, anxiety, sleep habits, and social media use relate to feelings of being a fraud (impostor phenomenon). Researchers aim to identify which psychological, behavioral, and structural factors mo…

This trial tests whether two mental training methods, computer-based multiple object tracking and mental imagery, can improve tennis performance, thinking skills, anxiety, and body responses in university students taking a tennis course. Participants either practiced tracking mov…

This pilot study is testing a program called Tiwahe Tewichaglapi, which adapts the Family Acceptance Project for Lakota 2SLGBTQ+ youth and their caregivers. The goal is to see if the program is acceptable, safe, and feasible, and to check if it helps reduce depression, anxiety, a…

This study tests whether brain scans and decision-making tasks can predict how well people with anxiety and depression respond to different types of talk therapy. Participants will be randomly assigned to one of three therapies: behavioral activation, exposure-based therapy, or s…

This observational study looks at whether voice characteristics can be linked to symptoms of depression and anxiety. Researchers will analyze voice recordings and mental health questionnaires from people who used the Kintsugi Voice Journaling app. The goal is to see if voice biom…

This trial explores whether adding simulation-based training to standard theoretical lessons helps midwifery students learn more about oxytocin induction and feel less anxious about it. Third-year midwifery students are randomly assigned to receive either theory alone or theory p…

This study aims to understand how common depression and anxiety are among parents involved with Swedish child welfare services due to child maltreatment or other family risks. Parents will fill out questionnaires about their symptoms and background. The results will be compared w…

This study tests a new approach called the Collaboration-Screening-Referral (SSH) model, which aims to identify parents involved with child welfare services who may have depression or anxiety. Social workers will be trained to use screening questionnaires and refer parents to men…

This study tests a three-session virtual program designed to help U.S. adults improve their social connections, get more involved in their communities, and feel better physically and mentally. Researchers will enroll 200 people who will attend weekly Zoom meetings with trained fa…

This study asks whether a single 30-minute session of moderate exercise can raise natural brain chemicals called endocannabinoids and improve thinking, stress, and mood in children and teens aged 9 to 17. Participants are randomly assigned to brisk walking or jogging on a treadmi…

This trial investigates whether paroxetine, a drug used for anxiety, affects the heart's electrical activity (QT interval) in healthy adults. Participants will take increasing doses of paroxetine, and their heart rhythm will be monitored via ECG. The study aims to see if any dose…

This study aims to understand the lived experiences of family caregivers who provide unpaid care to people with mental health conditions like depression, anxiety, and trauma in Zambia during the COVID-19 pandemic. Researchers will interview caregivers and mental health experts to…

This study tests whether a French version of the Pain Sensitivity Questionnaire (PSQ) accurately measures a person's natural sensitivity to pain. The PSQ uses 17 questions about everyday situations that might cause pain. Researchers will compare answers from healthy volunteers an…

This study tests an 8-week school program called INSPIRE, designed to help Indonesian teenagers aged 13-15 learn about mental health, build resilience, and reduce symptoms of depression and anxiety. Trained school counselors deliver the program using lesson plans and activities, …

This study will test whether an AI-generated educational program can improve how mothers manage their children's fevers and reduce their anxiety. Eighty mothers of young children visiting a Turkish emergency department will be split into two groups: one gets the AI-based training…

This study looks at how mepolizumab (Nucala), a treatment for severe eosinophilic asthma, impacts emotions and mental well-being in patients and their partners. Researchers will track changes in feelings like anxiety, depression, and stress using questionnaires and interviews. Th…

This study looks at how fear of pain affects movement in 26 healthy adults. Researchers used verbal suggestions and inactive electrodes to create a sense of threat during walking and arm-pointing tasks. The goal is to understand how fear of movement changes walking speed, stride,…

This study looks at whether certain slow brain waves in the prefrontal cortex can be a sign of social anxiety. Researchers will measure brain activity in 30 people with social anxiety disorder while they wait to give a speech. The goal is to better understand the brain's role in …

This study tested whether three weekly sessions of basic disaster awareness education could improve disaster literacy and reduce earthquake anxiety in adolescents aged 10-14. A total of 128 students from two middle schools in Erzincan took part, with half receiving the education …

This completed study looked at how well a collaborative care model works for common mental health issues like anxiety and depression in four French health clinics. The model involves a care manager who coordinates between family doctors and mental health specialists. Researchers …

This study tested whether using augmented reality (AR) or a 3D hip model helps first-year nursing students learn how to give intramuscular injections better than traditional methods. 146 students were randomly assigned to practice with AR, a 3D model, or a standard model. Researc…

This study looked at whether an adaptive e-learning course on urgent medical conditions could reduce anxiety and improve skills in junior doctors starting work in emergency departments. 233 new doctors were randomly assigned to either take the course in their first six weeks or r…

This study looked at 103 adults with narcolepsy or obstructive sleep apnea to see if anxiety, social, or work factors affect their ability to stay awake during a standard test. Participants filled out an anxiety questionnaire before the test. The goal is to better understand why …

This study gave 100 healthy adults either 50 mg of CBG or a placebo to see how it affects anxiety, stress, mood, memory, and physical signs like heart rate and blood pressure. Researchers also tracked side effects like sleepiness or dry mouth. The goal is to better understand bot…

This study tested whether daily mood check-ins via a mobile app could help predict and prevent depression in people who recently had a stroke. Over 400 participants used the app for three months while researchers tracked their emotional symptoms. The goal was to see if this kind …

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study looked at how often older adults feel anxious or depressed after breaking a bone from a fall and having surgery. Researchers used a simple questionnaire to check symptoms in 40 patients aged 65 and older, both those who had surgery and those who did not. The goal was t…

This study aimed to find simple ways to predict how much pain people will feel after oral surgery, like having a tooth pulled. Researchers measured things like pain sensitivity before the procedure in 148 adults. The goal was to create a model that helps doctors plan better pain …

This study looked at 38 people who had a first stroke in the cerebellum, a brain area involved in mood. Researchers used interviews and smartphone tracking to measure depression, anxiety, and apathy in daily life. The goal was to better understand how these mood problems develop …

This study looks at 128 children who were part of an early intervention program in infancy and are now teenagers. Researchers measure brain activity, stress responses, and behaviors like risk-taking and mood to see if early help made a difference. No new treatment is given; this …

This study looked at 60 teens ages 12 to 18 to see if those with Avoidant and Restrictive Food Intake Disorder (ARFID) had more feeding problems before age 4 compared to healthy teens. Researchers used questionnaires to check early feeding history, growth, and sensory sensitiviti…

This study looked at whether adding specialty palliative care early on to standard intensive care can improve the experience for critically ill older adults (age 60+) and their families. Over 1,000 patients and their family members took part. The goal was to see if this approach …

This study surveyed over 750 adult patients before elective surgeries to learn about their anxiety and find out which calming methods they find helpful. Participants answered anonymous questionnaires about their feelings and preferences. The goal was to gather information to impr…

This completed study looked at how constant noise in intensive care units (ICUs) affects healthcare workers. Researchers compared 102 ICU and ward staff on hearing, anxiety, and noise sensitivity. The goal was to see if long-term exposure to ICU noise is linked to health problems…

This study looked at whether simulation-based training for vaginal exams helps midwifery students feel less anxious and more confident. 67 third-year students were split into two groups: one practiced on a simulator in a lab, the other in a real clinical setting. Results showed t…

This study looked at how children ages 8 to 17 use smartphones and tablets, including social media and games, and how that relates to their mental health, sleep, and physical activity. Over 900 children and their parents used the Aura app and completed surveys for three months. T…

This study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…

This study tested whether holding a newborn skin-to-skin right after a C-section (within 5 minutes) or within the first hour helps with breastfeeding, reduces anxiety, and keeps mom and baby healthy. 92 mothers and their newborns took part. The results showed that early contact c…

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group t…

This study measured anxiety in 300 adults before they underwent allergy testing. Researchers used a simple 0-to-10 scale and a questionnaire to gauge how anxious patients felt. The goal was to better understand what affects a patient's experience and how anxiety might influence t…

This study tested whether a one-hour class on climate change and pregnancy could help pregnant women feel more aware, less anxious, and more hopeful about the future. 154 pregnant women were split into two groups: one received the class, the other did not. Researchers measured th…

This study looked at how parents cope emotionally after their child is hospitalized in intensive care for a severe injury. Researchers checked for signs of anxiety, depression, and post-traumatic stress in 62 parents, 3 to 6 months after the child left the ICU. The goal was to un…

This study tested an AI tool called LyssnCBT that listens to therapy sessions and gives therapists feedback on how well they are using cognitive behavioral therapy (CBT). Researchers worked with 449 therapists, supervisors, and clients at five community mental health agencies in …

This completed study looked at how common depression and anxiety are in teenagers with cystic fibrosis and their parents. Researchers used questionnaires during routine clinic visits to screen for symptoms. The goal was to better understand mental health needs in this group.

This study looked at how the brain develops over time in young teenage girls who have hurt themselves on purpose (non-suicidal self-injury). Researchers used interviews, brain scans (MRI), and thinking tests to understand the condition better. A total of 168 girls took part, incl…

This study tested a special fiber-optic sensor that can measure breathing and heart rate during MRI scans. The goal was to see if these measurements could show how anxious a patient feels. 200 MRI patients took part, and their sensor readings were compared to anxiety questionnair…

This study measured anxiety levels in 543 nurses who have worked in psychiatric settings for over a year. Researchers used a standard anxiety questionnaire to understand how stress from unpredictable patients, violence risk, and emotional demands affects these healthcare workers.…

This study tested a new online program (iACTforDGBI) for people with disorders of the gut-brain interaction, like IBS, who also have anxiety or depression. 30 participants tried the self-guided sessions and gave feedback through interviews and questionnaires. The goal was to see …

This completed study in Slovakia examined how psychological factors like resilience, stress, and positive thinking relate to the body's immune system. Researchers measured immune markers in blood and compared them to mental health questionnaires in 700 adults, including people in…

This completed study looked at how common cognitive (thinking) difficulties are in 150 people with myasthenia gravis. Researchers measured memory, attention, and other mental skills, and how these issues affect daily activities, work, and quality of life. The goal is to better un…

This study examined anxiety, depression, fatigue, and quality of life in 20 adults with Behçet's disease using questionnaires. Researchers aimed to understand the psychological symptoms that often accompany this rare inflammatory condition. The study was observational and did not…

This study tested whether combining mental health treatment with job coaching helps people on sick leave due to anxiety, depression, stress, personality disorders, or functional disorders return to work. 900 participants in Denmark received either the combined service or usual ca…

This study looked at 206 medical residents in France to see if their physical activity levels are linked to anxiety, depression, and burnout. Participants filled out online surveys about their exercise habits and mental health. The goal is to understand whether staying active mig…

This completed study looked at 72 adults to see how certain chemicals (Substance P and CGRP) in saliva and tooth pulp relate to dental pain, inflammation, and stress. Participants provided saliva samples and had pulp tissue collected during routine root canal treatment. The goal …

This study tested whether keeping a hospital diary during a child's stay in the pediatric intensive care unit (PICU) could improve mental health outcomes for families. Over 400 families participated across four PICUs in Rio de Janeiro. Researchers measured anxiety, depression, PT…

This study followed 127 first-time mothers to see if their sleep quality, anxiety levels, and nighttime phone use before labor were linked to how long labor lasted and whether they needed extra medical help. Participants filled out questionnaires during routine checkups, and rese…

This study looked at whether a quick screening when patients leave the intensive care unit (ICU) can predict if they will have psychological issues (like depression or anxiety) or new physical disabilities three months later. Researchers followed 773 adults who stayed in the ICU …

This study followed 2,365 adults from urban areas of Chile for 12 months to learn more about chronic pain and its effects. Researchers looked at how chronic pain relates to mental health issues like depression and anxiety, as well as work stress and daily functioning. The goal wa…

This study looked at how inflammation affects feelings of pleasure and motivation in older adults (ages 60-80) with anxiety. Researchers used brain scans and computer tasks to measure reward responses. The goal was to better understand the link between anxiety, inflammation, and …

This completed study followed 1,290 adults with type 1 or type 2 diabetes for two years. Researchers tracked mental health issues like depression, anxiety, and eating problems alongside daily blood sugar levels using smartphone surveys and continuous glucose monitors. The goal wa…

This study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…

This study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …

This study tested a community-based mental health screening and referral program for women aged 18-49 affected by floods in rural Pakistan. Trained health workers screened nearly 4,800 women for anxiety and depression, referred those with symptoms for counselling, and tracked how…

This study followed 19 teens and young adults with cystic fibrosis to see how starting the drug ORKAMBI changed their anxiety, depression, quality of life, and how well they stuck to their treatments. Researchers compared those taking ORKAMBI to a similar group not on the drug. T…

This study looked at whether a school program called MindUP, which teaches mindfulness, can improve mental health and school performance in 5th to 8th graders. About 68 students from Alabama schools took part. Researchers measured changes in anxiety, attention, and stress to see …

This completed study tested a tablet-based screening system for substance use, depression, and anxiety in over 10,000 HIV-positive adults during routine clinic visits. Patients who screened positive were offered behavioral treatments like motivational interviewing and cognitive b…

This study analyzed electronic medical records of nearly 920,000 Canadian adults to see how the COVID-19 pandemic affected primary care for chronic conditions like diabetes, heart failure, and depression. Researchers compared care before and during the pandemic, looking at visits…

This study looked at 25 people with FOXP1 syndrome, a rare genetic condition, to better understand their psychiatric symptoms. Researchers used interviews and questionnaires with families to assess hyperactivity, attention, anxiety, autism traits, and more. The goal is to improve…

This study looked at 21 children, teens, and young adults who had surgery for Moyamoya disease, a rare brain vessel condition. Researchers used questionnaires to measure anxiety, depression, attachment, and quality of life in patients and their parents. The goal was to understand…

This study looked at how people with high anxiety process emotional faces, since they often struggle to tell safe from threatening situations. Twenty-three young adults completed brain scans and some returned months later for a computer training task that teaches them to spot tin…

This study looked at how healthy young adults (ages 18-35) suppress negative emotional memories. Researchers used EEG to track brain activity while participants performed memory-suppression tasks. The goal was to better understand the brain's natural ability to forget unpleasant …

This study looked at how many hospital workers had COVID-19 antibodies and how long they lasted. Over 500 staff at a French cancer center gave blood samples and answered questionnaires at the start, 3 months, and 12 months. The goal was to understand immune response in people who…