Simple sedative may shield seniors from Post-Surgery confusion

NCT ID NCT06963112

Completed Symptom relief Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This study tests whether giving a small amount of the sedative midazolam during anesthesia can lower the risk of delirium (sudden confusion) and anxiety in older adults after surgery. About 612 patients aged 65-85 having non-heart, non-brain surgery will be randomly assigned to receive either midazolam or a placebo. The goal is to see if this common drug can help prevent mental side effects after an operation.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DELIRIUM

Contacts and locations

Locations

Changhai Hostpital of Navy Medical University

Shanghai, China
China-Japan Union Hospital of Jilin University

Jilin City, China
Chinese PLA General Hospital

Beijing, 100853, China
The First Affiliate Hospital of Guangxi Medical University

Guangxi, Guangxi, China
The Second Norman Bethune Hospital of Jilin University

Jilin City, China

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