Chinese Pla General Hospital

This early study tests a new treatment called KSVCBD for people with a type of blood cancer called B-cell non-Hodgkin's lymphoma that has come back or not responded to other treatments. KSVCBD is a special therapy that works inside the body to help immune cells attack cancer cell…

This phase 2 trial tests a combination of three drugs—zanubrutinib, rituximab, and venetoclax—in people with previously untreated follicular lymphoma. The goal is to see if this mix can improve the rate of complete remission (disappearance of cancer). Participants receive all thr…

This study tests a stem cell treatment called Amimestrocel in 120 people with diabetic kidney disease. The cells are given through an IV multiple times over 6 months. Researchers will check if it lowers protein in urine and improves kidney function. The goal is to see if this app…

This study tests whether Amimestrocel, a stem cell therapy from umbilical cords, can help people with acute kidney injury. Fifty adults aged 18 to 75 will receive the cells through an IV on four days. Researchers will check kidney function and safety over time.

This early-phase trial is testing a new type of immune cell therapy called CLEAR CAR-T (ET-970) in 30 people with advanced clear cell kidney cancer that has not responded to at least two prior treatments. The therapy uses donor immune cells engineered to target a protein called C…

This study tests a new combination of drugs (venetoclax, azacitidine, chidamide, and others) against the standard chemotherapy for adults aged 60-75 with newly diagnosed acute myeloid leukemia (AML). The goal is to see if the new combo leads to more remissions and fewer side effe…

This early-stage trial tests whether stem cells from the placenta, given through an IV, are safe and might help people recover from a recent stroke. About 24 participants will receive either the stem cells or a placebo. Researchers will track their recovery over two years, focusi…

This study tests a new treatment made from specially engineered immune cells (T cells) donated by healthy people. The cells are designed to better recognize and kill cancer cells while lasting longer in the body. The trial includes 24 adults with blood cancers or solid tumors tha…

This early-stage trial is testing a new treatment called KSVCBD for people with multiple myeloma that has come back or not responded to at least three prior treatments. KSVCBD is a type of CAR-T cell therapy given directly into the body to target two proteins (CD19 and BCMA) on m…

This study tests whether adding budesonide capsules early to standard blood-pressure and sugar-lowering drugs can reduce protein in the urine of people with IgA nephropathy, a kidney disease. Thirty adults with newly diagnosed disease will take the combination for 9 months, then …

This study tests a new type of CAR-T cell therapy for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to treatment. The therapy uses donor immune cells that are modified to target cancer cells and last longer in the body. The goal is to…

This study compares a new treatment (venetoclax plus CACAG) to the standard chemotherapy for adults newly diagnosed with intermediate- or high-risk acute myeloid leukemia (AML). About 160 participants aged 14 to 75 will be randomly assigned to one of the two groups. The main goal…

This study tests a new approach for treating hyperthyroidism (overactive thyroid) by combining a minimally invasive heat procedure with standard medication. About 454 adults with hyperthyroidism will receive thermal ablation to destroy overactive thyroid tissue, plus antithyroid …

This study tests whether adding two drugs (ruxolitinib and chidamide) to standard chemotherapy before a stem cell transplant can lower the chance of leukemia coming back. It involves 50 people aged 12–65 with high-risk B-cell acute lymphoblastic leukemia who have a suitable donor…

This study tests whether adding the immunotherapy drug camrelizumab to standard chemoradiotherapy can make rectal tumors disappear completely in people with a common type of locally advanced rectal cancer. About 44 adults aged 18-75 with tumors within 10 cm of the anus will recei…

This study compares two treatments for acute monocytic leukemia, a blood cancer. About 204 people aged 14 to 60 will get either a new drug combo (venetoclax plus CACAG) or standard chemotherapy (3+7). The goal is to see which approach leads to more complete remissions after one c…

This early-phase trial tests whether specially engineered immune cells (EBV-TCR-T cells) can safely control Epstein-Barr virus infections in people who have had a stem cell transplant. About 12 participants will receive one to three infusions of donor-derived cells. The main goal…

This Phase 2 trial tests whether adding venetoclax to a five-drug regimen (CACAG) works better than standard treatments for people whose acute myeloid leukemia has returned or not responded. About 200 adults aged 14 to 75 will be randomly assigned to one of the two approaches. Th…

This study tests a new sliding compression locking plate for treating fresh femoral neck fractures (a type of hip fracture). The goal is to see if this plate is safer and works better than current methods. About 1,150 adults who need surgery for this fracture will take part. The …

This study compares two treatments for low-risk papillary thyroid cancer: standard surgery and a less invasive option called ultrasound-guided thermal ablation, which uses heat (radiofrequency, microwave, or laser) to destroy tumors. Researchers will track about 3,700 patients ag…

This study tests whether adding two drugs, ruxolitinib and decitabine, to the standard chemotherapy given before a stem cell transplant can lower the chance of leukemia returning in high-risk patients. About 200 adults and teens with acute myeloid leukemia in first remission will…

This study is testing whether adding eculizumab to standard steroid therapy helps people having an acute attack of neuromyelitis optica spectrum disorder (NMOSD). Researchers will follow 200 patients in China, comparing those who get eculizumab plus steroids to those who get ster…

This phase 2 trial tests whether adding eliglustat (a GSL synthetase inhibitor) to standard treatments can help shrink tumors or slow cancer growth in people with advanced colorectal cancer that has not responded to at least two prior treatments. About 120 participants will be ra…

This study tests a new first-line treatment for people with advanced colorectal cancer that cannot be removed by surgery or has spread. The treatment combines two drugs, levozolinate and 5-FU, given together through an IV. The goal is to see if this approach helps control the can…

This study tests a combination of drugs (Chidamide, Decitabine, and an anti-PD-1 antibody) for people with classical Hodgkin lymphoma that has come back or not responded to treatment, and who cannot or choose not to have a stem cell transplant. The goal is to see if this combo he…

This study tests whether adding the drug eliglustat to CD30-targeted immunotherapy can make the treatment work better for people with CD30-positive lymphoma. About 40 adults who have already tried at least one other cancer treatment will receive either a CAR-T cell therapy or an …

This study tests a new treatment called RAK cell therapy, made from human umbilical cord blood, for people with advanced stomach cancer that has spread or come back after standard treatment. The goal is to see if it can help patients live longer and keep the cancer from growing, …

This study tests a new drug called pegmolesatide, alone or combined with roxadustat, to treat anemia in 240 adults on dialysis for chronic kidney disease. Participants currently on another anemia drug (rHuEPO) will switch to one of three treatment plans for 24 weeks. The goal is …

This Phase 2 trial tests a personalized cell therapy called anti-BCMA-CD19 CAR-T cells in 9 adults with IgG4-related disease that hasn't responded to standard treatments. Participants receive an infusion of their own modified immune cells after a short course of chemotherapy. The…

This study is testing whether a new type of CT scan, called photon-counting CT, can do it all in one go for people who have had a coronary stent placed. The scan aims to check the stent and arteries, measure blood flow to the heart muscle, and assess heart function in a single ex…

This study compares two types of CT scans for imaging the buildup of plaque in the carotid arteries, which supply blood to the brain. The newer photon-counting detector CT (PCD-CTA) will be compared with the standard energy-integrating detector CT (EID-CTA) in 100 people with car…

This study is testing a new wearable ultrasound sensor that sticks to the skin like a patch. The goal is to see if it can help doctors find and monitor deep vein thrombosis (blood clots) and heart conditions early, without needing bulky machines. About 300 adults with heart failu…

This study tests whether using a lung water monitor to tailor fluid intake can prevent acute kidney injury in elderly patients with kidney disease who are undergoing coronary angiography. 320 participants will receive hydration rates adjusted based on their lung water levels. The…

This early study tests whether a steam treatment guided by MRI can safely shrink an enlarged prostate and improve urinary symptoms. About 30 men with moderate-to-severe symptoms who haven't responded well to medication will receive the procedure. Researchers will measure changes …

This study looks at whether a pulmonary rehabilitation program—including exercise training, education, and behavior changes—can help patients who need high flow oxygen therapy. Researchers will measure muscle strength, breathing, and daily living skills in 70 participants. The go…

This study looks at whether the presence and distribution of H. pylori bacteria in the stomach, along with tissue features of early gastric cancer, can help predict how the cancer will behave and what the long-term outlook may be. Researchers will analyze data from about 1,500 pe…

This study aims to validate the 2025 ASAS-SPARTAN classification criteria for axial spondyloarthritis (axSpA) in Chinese patients with chronic back pain. AxSpA is a chronic inflammatory spine disease often misdiagnosed. Researchers will compare the new criteria against standard c…

This study looks at how well ultrasound-guided heat ablation works for non-cancerous thyroid nodules and aims to create an AI model that can predict treatment results. Researchers will follow 1500 adults who choose this minimally invasive procedure instead of surgery. The goal is…

This study looks at whether a special breathing therapy called OLE (Oscillatory Lung Expansion) helps ICU patients with pneumonia clear mucus from their lungs. Researchers will use a lung imaging tool (EIT) to see how well the therapy works. About 62 adults in the ICU will take p…

This study is a large survey of over 12,500 men aged 40 and older across China. Its goal is to find out how common lower urinary tract symptoms are and how they affect quality of life. Researchers will use questionnaires and tests to gather information, aiming to improve understa…