Chinese Pla General Hospital

This study aims to see if combining a traditional Chinese herbal formula with a special virus therapy can help people with severe pneumonia caused by bacteria that don't respond to standard antibiotics. Researchers will enroll 240 adults with this hard-to-treat infection to test …

This early-stage study is testing the safety and initial effectiveness of a new two-part treatment for advanced colorectal cancer that has spread to the liver and hasn't responded to standard therapies. About 25-30 patients will receive injections of a genetically engineered viru…

This study aims to find the best personalized dose of the antifungal drug isavuconazole for people over 60 with serious lung fungal infections. Researchers will check drug levels in the blood and see how patients respond to different doses to improve treatment safety and effectiv…

This early-stage study is testing a non-surgical procedure that uses focused sound waves guided by an MRI machine to treat a small area deep in the brain. The goal is to see if this approach is safe and can reduce the number of seizures in adults whose epilepsy is not controlled …

This study aims to create a personalized dosing system for a powerful antibiotic called ceftobiprole in patients aged 60 and older. It will enroll 150 older patients to measure drug levels in their blood and adjust their doses in real-time. The goal is to find the perfect dose fo…

This study tests a new treatment for a severe type of pneumonia that doesn't respond to antibiotics. It will involve 248 patients on breathing machines who have infections from 'superbugs.' The treatment uses special viruses, called bacteriophages, inhaled into the lungs to targe…

This study is testing whether combining two drugs, tunlametinib and an anti-EGFR antibody, can help control advanced colorectal or pancreatic cancer in patients whose cancer has a specific genetic change called a RAS mutation. It will involve about 90 adults whose cancer has wors…

This study is testing if a simple spray of numbing medicine into the chest during lung surgery can reduce the sharp pain patients often feel from their drainage tubes afterward. Researchers will compare two different numbing sprays against a placebo spray in 300 adults having min…

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear during heart surgery can help prevent post-surgery confusion (delirium) and reduce feelings of anxiety and depression. About 270 patients having planned heart surgery will be randomly assigned to re…

This study is testing if giving a low dose of the drug esketamine during surgery can help reduce anxiety and depression in breast cancer patients who already have mild to severe depression. It will involve 142 women undergoing breast cancer surgery. Researchers will compare those…

This study is testing if giving a low, continuous dose of a drug called esketamine (related to ketamine) during breast cancer surgery can help reduce the anxiety and depression many patients feel around their operation. It will involve about 218 patients and will measure their em…

This study aims to see if giving the drug esketamine during surgery can help reduce anxiety and depression symptoms in breast cancer patients who also have severe depression. It will involve about 240 female patients undergoing breast cancer surgery. Researchers will compare thos…

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear during breast cancer surgery can help reduce feelings of anxiety and depression that often occur around the time of an operation. About 232 patients will be randomly assigned to receive either the r…

This study is testing whether a single medical device called Medstrom can effectively monitor pain, sedation level, and muscle relaxation during colon cancer surgery. Currently, doctors use multiple separate devices for these measurements, which can be complicated and sometimes g…

This study aims to find out if a special brain scan taken before surgery can predict which older patients with type 2 diabetes are most likely to experience confusion and delirium after an operation. Researchers will enroll 154 patients scheduled for liver tumor surgery and measu…

This study aims to understand the relationship between urinary function (like bladder control and flow) and the development of other common age-related health problems, such as diabetes, heart disease, and high blood pressure. It will follow 500 Beijing residents aged 60 and olde…