Virus-Immunotherapy combo targets Hard-to-Treat colorectal cancer

NCT ID NCT07411781

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a combination of a specially modified virus (PIN) and an immunotherapy drug (sintilimab) in about 25 adults with advanced colorectal cancer that has spread to the liver and has not responded to at least two prior treatments. The main goals are to check the safety of the combination and see if it can shrink tumors. Participants must be between 18 and 75 years old and have a specific type of colorectal cancer called pMMR/MSS.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Biotherapeutic Department and Hematology Department of Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100853, China