Sound waves vs. seizures: new ultrasound treatment for epilepsy

NCT ID NCT07249190

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests whether focused ultrasound waves can safely reduce seizures in 20 adults with drug-resistant epilepsy. The procedure uses MRI guidance to precisely target a small brain area involved in seizure spread. Researchers will monitor side effects and seizure frequency for two years to see if this non-surgical approach works.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
MR-guided focused ultrasound (procedure)
What this could lead to
If successful, this could offer a non-invasive option to reduce seizures in people with drug-resistant epilepsy, potentially improving quality of life.
What could go wrong
This is a very early Phase 1 trial with only 20 people. The procedure may not reduce seizures, and risks include side effects from brain ablation, MRI claustrophobia, or radiation exposure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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