Sound waves aimed at the brain could ease seizures

NCT ID NCT07353918

ENROLLING_BY_INVITATION Symptom relief Sponsor: Carilion Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small study tests whether low-intensity focused ultrasound (LIFU) can safely reduce seizures in people with temporal lobe epilepsy that doesn't improve with medication. Six participants with implanted brain electrodes will receive both real and sham ultrasound sessions. The main goal is to see if seizure frequency changes, and researchers will also track side effects and symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low-intensity focused ultrasound (LIFU) device
What this could lead to: If it works, this could point toward a non-invasive way to reduce seizures in people with epilepsy that doesn't respond to medication.
What could go wrong: This is a very early, tiny study with only 6 people. It's invite-only and uses a sham comparison, so results may not apply widely or show clear benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy mesial temporal lobe epilepsy with hippocampal sclerosis visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY (TREATMENT REFRACTORY) EPILEPSY COMORBIDITIES

Contacts and locations

Locations

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, 24016, United States

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