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Spotting the warning signs of drug-resistant epilepsy in children

NCT ID NCT07723287

Knowledge-focused Sponsor: Pham Ngoc Thach University of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused This study
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study follows 375 children with epilepsy to find early clues—from brain wave patterns and clinical features—that may predict which cases become resistant to standard medications. Researchers will use statistical models and machine learning to build a risk profile. The goal is to help doctors intervene sooner in children at highest risk for difficult-to-control seizures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify children at high risk for drug-resistant epilepsy earlier, potentially guiding more aggressive or alternative treatments sooner.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test any new therapy. The findings may not apply to all children or healthcare settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 375 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children diagnosed with epilepsy receiving care at Children's Hospital 1, Ho Chi Minh City, Vietnam.

Ages

Up to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children younger than 16 years, including neonates. * Diagnosed with epilepsy according to International League Against Epilepsy criteria. * Receiving treatment or follow-up at Children's Hospital 1. * Parent or legal guardian provides informed consent. * Expected follow-up of at least 12 months. Exclusion Criteria: * Poor treatment adherence. * Insufficient baseline data. * Lost to follow-up. * Psychogenic nonepileptic seizures. * Severe systemic illness interfering with antiseizure medication. * Acute symptomatic seizures.

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Conditions

The condition(s) this trial relates to.

epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epilepsy Epilepsy (treatment refractory)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Children's Hospital 1, Ho Chi Minh City, Vietnam

    Ho Chi Minh City, Hồ Chí Minh, Vietnam

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