Mapping the Brain's electrical signals to improve surgical precision
NCT ID NCT00575081
First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time
Summary
This study aims to build a comprehensive 'physiological brain atlas' by collecting electrical and other data from patients undergoing stereotactic brain surgery for conditions like Parkinson's disease, OCD, and epilepsy. The goal is to map this information onto a standard brain template, which could help doctors understand and treat brain disorders more precisely. The study will include up to 5,000 patients aged 6 to 90 who are already scheduled for such procedures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Stereotactic brain procedures
- What this could lead to
- If successful, this could create a detailed brain atlas that helps doctors target treatments like deep brain stimulation more precisely for conditions such as Parkinson's disease and epilepsy.
- What could go wrong
- This is an observational data-collection effort, not a treatment trial, so it may not directly improve outcomes. The atlas's usefulness depends on complex data analysis and may not generalize to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Aug 2006
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who have already consented to having a stereotactic brain procedure for surgical treatment or implantation of a device to treat any brain disease. This includes patients who are undergoing normal neurosurgical care for the treatment of their movement disorder (like tremor and Parkinson's disease), epilepsy, pain, or psychiatric disease.
- Ages
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6 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients who are recommended for Stereotactic Brain procedures * Any patient who has agreed to undergo a Stereotactic Brain procedure * Patients age under 6 -90 years old Exclusion Criteria: * Patients who fail recommendation for Stereotactic Brain procedures * Patients not consented for Stereotactic Brain procedures * Patients outside the age range of 6 -90 years old * Patients or legal guardians not able to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Vanderbilt Univeristy
RECRUITINGNashville, Tennessee, 37232, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can stem cells boost brain surgery for epilepsy?
- A genetic roadmap for Parkinson's: testing thousands to unlock clues
- Can magnetic pulses ease OCD in teens who Haven't improved?
- Can a focused electric field quiet the Brain's obsessive signals?
- Can gentle touch therapy calm Parkinson's tremors?