Transcranial direct current stimulation (tDCS) to treat patients with severe and resistant obsessive compulsive disorder
NCT ID NCT03304600
First seen Sep 09, 2026 ยท Last updated Sep 09, 2026
Summary
It's a multicentric, randomized, controlled study concerning 100 patients with treatment-resistant obsessive compulsive disorders (OCD). The aim of this study is to evaluate the effect of transcranial direct current stimulation (tDCS) on OCD patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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83 people
The number who actually took part.
- Started
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Nov 2017
- Finished
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Feb 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meets criteria for obsessive compulsive disorder according to Diagnostic and Statistical Manual (DSM IV) with a "good insight" (BABS) * No current depressive and suicidal risks * No epileptic pathology * Age: Participants will be both males and females, 18-70 years of age included. * Chronic Obsessive compulsive disorder ( Total Y-BOCS\>20 or Y-BOCS one subscale \> 15) * Obsessive compulsive disorder resistant to pharmacology treatment : 1. at least 2 antidepressants (IRS type) (\> 12 weeks) 2. cognitive and comportment therapy since at least one year * Treatment stability (antidepressants) for more than 12 weeks without significant improvement. * Affiliation to a social security system (recipient or assignee), * Signed written inform consent form Exclusion Criteria: * Female subject who is pregnant, or of child-bearing age, sexually active and not using reliable contraception or who is nursing, * Patient under curators * Patient hospitalized under duress * Meets another diagnosis of axe 1 of DSM-IV * Current depressive or suicidal risks * Patient with any form of metal in the cranium, a pacemaker, skull defects, or skin lesions to the scalp (cuts, abrasions, rash) * Epileptic patient * Patient with a medical history of cranial trauma * Patient unable to give his or hers informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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C.H. Guillaume Regnier
Rennes, 35703, France
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CHU de Nantes
Nantes, 44093, France
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Centre Hospitalier Henri Laborit
Poitiers, 86021, France
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Hospices Civils De Lyon
Lyon, France
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Other studies related to the condition(s) this trial covers.
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