ESSENTIAL TREMOR

This study is testing whether a gentle, focused ultrasound beam can safely calm overactive brain areas in people with movement disorders like Parkinson's or essential tremor, and conditions like epilepsy or addiction. Researchers will measure changes in brain activity and symptom…

This study is collecting real-world information on how a specific brain ablation procedure affects patients' quality of life. It will follow 200 people with Parkinson's disease, dystonia, or essential tremor who are scheduled to receive the treatment. The goal is to understand th…

This study is testing a non-surgical radiation treatment for people with severe hand tremor from Essential Tremor or Parkinson's disease. It aims to see if this one-time, outpatient procedure improves patients' quality of life and reduces shaking. Participants will complete quest…

This study tests whether a newer, more focused type of deep brain stimulation can better control essential hand tremor than the standard type. Researchers will compare how well each method reduces shaking while trying to avoid side effects like slurred speech or balance problems.…

This study aims to learn more about how deep brain stimulation (DBS) surgery helps control symptoms of Parkinson's disease, essential tremor, and dystonia. Researchers will observe 200 adults with these movement disorders who are having the standard DBS surgery. During the operat…

This study is creating a registry to track the real-world results of an already-approved brain implant treatment for essential tremor. It will follow 500 adults who have the implant to see how it affects their quality of life over time. The goal is to gather more evidence on how …

This study follows people for 3 years after they receive a focused ultrasound treatment for severe hand tremor that doesn't improve with medications. Researchers want to see if the tremor reduction lasts long-term and how it affects people's daily lives and brain health. About 24…

This study is testing whether a new drug called BP1.4979 can reduce shaking in adults with essential tremor. About 50 participants will take either the real drug or a placebo pill twice a day for four weeks. Researchers will compare the two groups to see if the drug is effective …

This study aims to make deep brain stimulation (DBS) therapy for essential tremor work better and be easier to set up. Researchers are testing a computer-guided method to help doctors find the most effective stimulation settings more quickly. The study involves 25 people who alre…

This study is testing a new 'smart' version of deep brain stimulation (DBS) for people with essential tremor, a condition causing uncontrollable shaking. The goal is to see if the implanted device can automatically turn off stimulation when it detects you are asleep, which may re…

This study is testing a new, smarter version of a brain implant for people with severe essential tremor whose current implant is no longer working well. The new system has two leads and is designed to detect when a tremor is about to start and deliver stimulation only when needed…

This study is testing a new, gentler pattern of deep brain stimulation for people with essential tremor, a condition that causes uncontrollable shaking, especially in the hands. Researchers want to see if this new approach, which uses lower currents in a specific pattern, is safe…

This study is for people with essential tremor who already had a focused ultrasound brain procedure on one side. It tests whether adding the same treatment to the other side of the brain works better than continuing with standard medication alone. Researchers will compare tremor …

This study aims to collect long-term safety and effectiveness data on Abbott's deep brain stimulation (DBS) systems. It will follow 1,000 patients with Parkinson's disease, essential tremor, or dystonia for five years after their device is implanted and programmed. The goal is to…

This study is testing a computer program called DystoniaNet that uses artificial intelligence to help doctors diagnose isolated dystonia, a movement disorder. The goal is to see if this tool can make diagnosis faster and more accurate, as current methods often lead to misdiagnosi…

This study is testing a new skin biopsy to see if it can identify which people with essential tremor are most likely to develop Parkinson's disease. Researchers will take small skin samples from 300 participants to look for a specific protein linked to Parkinson's. They will then…

This study is testing whether stimulating two specific brain areas with magnets can reduce hand tremors in people with essential tremor. Participants with shaking that isn't controlled by standard medications will receive five sessions of either real or fake brain stimulation. Re…

This study is testing a new wearable device designed to reduce hand tremors at home. It aims to see if gentle mechanical stimulation on the wrist can help people with Essential Tremor or Parkinson's Disease perform daily tasks more easily. Participants will use different versions…

This study is testing whether a non-invasive, focused ultrasound device can reduce hand tremor in people whose shaking doesn't improve with medication. It will involve 12 adults with Parkinson's disease tremor, essential tremor, or dystonic tremor. Researchers will use the NaviFU…

This study is testing an improved version of a non-surgical, FDA-approved ultrasound treatment for essential tremor, a condition that causes uncontrollable shaking. Researchers are using advanced 3D brain mapping to more precisely target and destroy the tiny brain area causing th…

This study aims to understand how alcohol affects shaking in people with different tremor conditions like essential tremor, dystonia, and Parkinson's disease. Participants will drink either an alcoholic beverage or a non-alcoholic placebo on separate days while researchers measur…

This study aims to understand how deep brain stimulation (DBS) treatment affects attention, eye movement, and emotion perception in people with Parkinson's disease and essential tremor. Researchers will track eye movements while participants view facial expressions before, during…

This study is testing whether low-energy sound waves, aimed at a specific brain pathway, can cause a temporary reduction in hand tremor for people with essential tremor. Researchers will test different settings of the sound waves on 60 participants who are already scheduled for a…

This study aims to understand how well deep brain stimulation (DBS) works in everyday practice for people with Parkinson's disease, essential tremor, or dystonia. Researchers will look back at the medical records of up to 5,000 people who have already had or are eligible for the …

This study aims to understand how the brain controls speech in people with Parkinson's disease, essential tremor, or dystonia. Researchers will record brain activity from 80 participants while they perform speech tasks during deep brain stimulation surgery. The goal is to learn h…

This study will examine how two important brain circuits - one involving the subthalamic nucleus (STN) and one involving the ventral intermediate nucleus of the thalamus (VIM) - contribute to learning and producing speech sequences. Participants will include two groups: 1. indivi…