3-D brain mapping could sharpen ultrasound treatment for hand tremors

NCT ID NCT06331052

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using 3-D tractography—a detailed brain imaging method—can make focused ultrasound ablation safer and more effective for people with essential tremor. Twenty-four adults with moderate to severe tremor that hasn't responded to medication will receive the procedure. Researchers will track side effects and tremor improvement over three months to see if this advanced imaging helps target the right brain area more precisely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MR-guided focused ultrasound ablation

What this could lead to

If successful, this could offer a more precise, non-invasive treatment option for essential tremor, potentially reducing side effects and improving tremor control.

What could go wrong

This is an early feasibility study with only 24 participants, so results may not apply to everyone. The procedure carries risks like temporary balance or speech issues, and long-term benefits are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

essential tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••