Zapping away tremors: scientists probe how electrical stimulation calms shaky hands
NCT ID NCT04501133
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study investigates how peripheral electrical stimulation (PES) to the forearm muscles can reduce tremors in people with Parkinson's disease or essential tremor, as well as in healthy volunteers. Researchers use brain and muscle recordings to understand the underlying nerve signals. The goal is to learn whether and how this non-invasive approach might one day offer tremor relief without medication or surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Peripheral electrical stimulation and single-pulse transcranial magnetic stimulation (TMS) delivered via devices
- What this could lead to
- If successful, this research could point toward a non-invasive, drug-free way to manage tremors in Parkinson's disease and essential tremor.
- What could go wrong
- This is an early-stage mechanistic study, not a treatment trial. It may not lead to a practical therapy, and individual results may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shirley Ryan AbilityLab
Chicago, Illinois, 60611, United States
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- Could a sleep disorder hold the key to Parkinson's pain?
- Could gentle electrical pulses steady shaky hands?