Zapping away tremors: scientists probe how electrical stimulation calms shaky hands

NCT ID NCT04501133

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study investigates how peripheral electrical stimulation (PES) to the forearm muscles can reduce tremors in people with Parkinson's disease or essential tremor, as well as in healthy volunteers. Researchers use brain and muscle recordings to understand the underlying nerve signals. The goal is to learn whether and how this non-invasive approach might one day offer tremor relief without medication or surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Peripheral electrical stimulation and single-pulse transcranial magnetic stimulation (TMS) delivered via devices
What this could lead to
If successful, this research could point toward a non-invasive, drug-free way to manage tremors in Parkinson's disease and essential tremor.
What could go wrong
This is an early-stage mechanistic study, not a treatment trial. It may not lead to a practical therapy, and individual results may vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shirley Ryan AbilityLab

    Chicago, Illinois, 60611, United States

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