Reading the Brain's signals to predict who benefits from deep brain stimulation

NCT ID NCT06813300

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Deep brain stimulation uses implanted electrodes to send electrical pulses to specific brain regions, and doctors are still working out how to tune it for each patient. This study records brain activity while adults with neurological or psychiatric conditions perform cognitive and movement tasks before, during, and after their deep brain stimulation procedure. Researchers compare those recordings with symptom scores to look for brain-activity patterns that predict how well the stimulation works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
electrophysiological recordings of brain activity during cognitive tasks
What this could lead to
If researchers can link specific brain-activity patterns to how well deep brain stimulation works, doctors could tune the therapy faster and more precisely for each patient.
What could go wrong
The study observes brain signals rather than testing a new treatment, so it may not find reliable biomarkers. Results from a single group of patients may not apply broadly, and recording brain activity during surgery carries the usual risks of the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2024

Expected to finish

Apr 2036

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patient * Patient suffering from a pathology requiring treatment with deep brain stimulation: neurological disease (e.g.: Parkinson Disease, Essential Tremors, dystonia, epilepsy, etc.) or psychiatric disease (e.g.: Obsessive Compulsive Disorder, depression, eating disorders, etc.). * Patient capable of understanding the study procedures and completing the self-questionnaires in French * Patient informed and having signed the informed consent form Exclusion Criteria: * Contraindications to DBS, neurosurgery or anesthesia * Patients with significant hemorrhagic or infectious risks * Patient unable to perform the neurocognitive or sensorimotor tests * Patient who is not a beneficiary of a social security system.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Grenoble-Alpes Hospital Center

    NOT_YET_RECRUITING

    Grenoble, 38043, France

  • Groupe Hospitalo-Universitaire Paris Psychiatrie et Neurosciences, Paris

    RECRUITING

    Paris, 75014, France

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