ESSENTIAL TREMOR

This study tests a precise, non-invasive radiation treatment called frameless virtual cone radiosurgery for people with severe tremor from essential tremor or Parkinson's disease who cannot have deep brain stimulation. The goal is to reduce tremor and improve daily activities. Fo…

This study tests a new type of deep brain stimulator for people with essential tremor, a condition that causes uncontrollable shaking. Unlike standard devices that stimulate the brain constantly, this "closed-loop" system only delivers stimulation when it senses tremor activity. …

This study tests whether a daily food supplement called PICOZYME ET, which contains an enzyme called ALDH, can reduce tremors and improve daily activities in people with essential tremor. Forty adults with stable medication will take the supplement for three months. Researchers w…

This study tests a new way to treat severe hand tremors caused by essential tremor or Parkinson's disease. Instead of using an invasive head frame or surgery, the treatment delivers radiation in three small doses using a standard linear accelerator. The goal is to reduce tremors …

This study tests a wristband device that uses mild nerve stimulation to help reduce hand tremors in adults with essential tremor who are already scheduled for deep brain stimulation (DBS) surgery. About 20 participants will use the device twice daily for three months. Researchers…

This study tests an experimental drug called ulixacaltamide against a placebo in 1000 adults with essential tremor, a condition that causes shaking hands. The main goal is to see if the drug improves daily activities like eating and writing over 8 to 12 weeks. Participants may th…

This study was designed to see if deep brain stimulation (DBS) of the VIM brain area changes breathing in people with essential or dystonic tremor. Researchers planned to measure breath-holding and peak airflow before and after surgery. However, the study was withdrawn before enr…

This study looks at how different patterns of deep brain stimulation (DBS) affect movement and brain activity in people with Parkinson's disease, essential tremor, multiple sclerosis, or dystonia. Researchers will test various stimulation patterns to find which ones work best for…

This study follows 100 people with essential tremor over about 5 years to learn more about different types of the condition and how it changes over time. Researchers will use brain scans, movement tests, and lab work to find markers that might help predict progression. The goal i…

This study aimed to test a new ultrasound-based imaging technique called Echo-Focusing for people with severe depression or essential tremor that didn't improve with standard treatments. The goal was to see if it was safe and could improve quality of life. However, the study was …

This study uses an Apple Watch to monitor how the benefits of deep brain stimulation (DBS) change throughout the day in people with essential tremor. About 50 participants who already receive DBS at Mayo Clinic will perform simple tasks while the watch records movement. The goal …