Brain implant learns to read OCD signals in tiny pilot study

NCT ID NCT03457675

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early study tests an adaptive deep brain stimulation (aDBS) system in 2 people with severe, treatment-resistant OCD. The device records brain signals to identify patterns linked to OCD distress and stimulation side effects. The goal is not to treat OCD now, but to gather data needed to build a future system that automatically adjusts stimulation for better symptom control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Deep brain stimulation (DBS) device
What this could lead to
If successful, this could pave the way for a smarter DBS system that automatically adjusts stimulation to better control OCD symptoms and reduce side effects.
What could go wrong
This is a very early, tiny study with only 2 participants, focused on gathering data rather than proving treatment works. The approach may not lead to a usable system.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Brown University

    Providence, Rhode Island, 02912, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

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