5-Year study tracks brain implant for Parkinson's and tremor

NCT ID NCT04071847

Recruiting now Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This international study is following 1,000 people who already have or are getting an Abbott deep brain stimulation (DBS) system to treat Parkinson's disease, essential tremor, or dystonia. Researchers will track how well the device controls symptoms and monitor for serious side effects over five years. The goal is to confirm the long-term safety and effectiveness of DBS for these movement disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deep brain stimulation (DBS) device
What this could lead to: If successful, this study could confirm that Abbott DBS systems provide lasting symptom control for movement disorders over many years.
What could go wrong: This is an observational post-market study, not a randomized trial, so results may be less definitive. There are also risks from surgery and the device itself, such as infection or lead movement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dystonia dystonic disorder essential tremor idiopathic torsion dystonia movement disorder Parkinson disease Tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSTONIA ESSENTIAL TREMOR MOVEMENT DISORDERS PARKINSON DISEASE PRIMARY DYSTONIA SECONDARY DYSTONIA TREMOR

Contacts and locations

Locations

Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Allegheny General Hospital Department of Neurosurgery
TERMINATED

Pittsburgh, Pennsylvania, 15212, United States
Az.Osp. Universitaria di Ferrara
TERMINATED

Cona, Emilia-Romagna, 44124, Italy
Beth Israe Deaconess Medical Center
ACTIVE_NOT_RECRUITING

Boston, Massachusetts, 02215, United States
CHU Gabriel Montpied
WITHDRAWN

Clermont-Ferrand, Auvergne, 63003, France
CHU Hopital Pasteur
RECRUITING

Nice, Provence-Alpes-Azur, 6002, France
CHU de St Etienne
ACTIVE_NOT_RECRUITING

Saint-Etienne, Auvergne, 42270, France
Cedars-Sinai Medical Center
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90048, United States
Center for Interventional Pain & Spine
WITHDRAWN

Exton, Pennsylvania, 19341, United States
Chang Gung Memorial Hospital
ACTIVE_NOT_RECRUITING

Linkou District, Ntaiwan, 333, Taiwan
Colorado Neurodiagnostics
TERMINATED

Littleton, Colorado, 80120, United States
Dartmouth Hitchcock Medical Center
ACTIVE_NOT_RECRUITING

Lebanon, New Hampshire, 03756, United States
Fondation Rothchild
WITHDRAWN

Paris, ILE, France
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
ACTIVE_NOT_RECRUITING

Milan, Lombardy, 20133, Italy
Helsinki University Central Hospital
RECRUITING

Helsinki, Uusimaa, 00290, Finland
Hospital Universitari Germans Trias I Pujol
RECRUITING

Badalona, Catalonia, 08916, Spain
Hospital Universitario de la Princesa
RECRUITING

Madrid, 28006, Spain
Hospital Virgen de Rocio
RECRUITING

Seville, Andalusia, 41013, Spain
Hualien Tzu Chi Hospital
RECRUITING

Hualien City, 97002, Taiwan
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Kansas University Medical Center
ACTIVE_NOT_RECRUITING

Kansas City, Kansas, 66160, United States
King's College Hospital
RECRUITING

London, SE5 9RS, United Kingdom
Medizinische Einrichtungen der Universität Düsseldorf
RECRUITING

Düsseldorf, North Rhine-Westphalia, 40225, Germany
Neurosurgery One
WITHDRAWN

Littleton, Colorado, 80122, United States
Ohio State Medical
RECRUITING

Columbus, Ohio, 43210, United States
Policlinico Universitario A. Gemelli
RECRUITING

Rome, Lazio, 00618, Italy
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Queen Elizabeth University Hospital
RECRUITING

Glasgow, Wdbtshr, United Kingdom
Royal Melbourne Hospital - City Campus
RECRUITING

Parkville, Victoria, 3050, Australia
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States
Southmead Hospita
WITHDRAWN

Bristol, South West England, BS10 5NB, United Kingdom
Texas Movement Disorder Specialist
ACTIVE_NOT_RECRUITING

Georgetown, Texas, 78628, United States
The Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44106, United States
The Walton Centre
ACTIVE_NOT_RECRUITING

Liverpool, North West England, L9 7LJ, United Kingdom
Thomas Jefferson Department or Neurosurgery
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UKE Hamburg (Universitatsklinik Eppendorf)
ACTIVE_NOT_RECRUITING

Hamburg, 20246, Germany
UNIVERSITATSMEDIZIN der Johannes Gutenberg-Universität Mainz
RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany
University of Aizona Health Sciences
ACTIVE_NOT_RECRUITING

Tucson, Arizona, 85274, United States
University of California at Davis
ACTIVE_NOT_RECRUITING

Sacramento, California, 95817, United States
University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States
University of Miami Hospital
ACTIVE_NOT_RECRUITING

Miami, Florida, 33136, United States
University of South Florida - Department of Neurology
RECRUITING

Tampa, Florida, 33612, United States
University of Utah Hospital
RECRUITING

Salt Lake City, Utah, 84132, United States
Universitäts Klinikum Tübingen
RECRUITING

Tübingen, Baden-Wurttemberg, 72076, Germany
Universitätsklinikum Münster
RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Universitätsklinikum des Saarlandes
RECRUITING

Homburg, Saarland, 66421, Germany
Willis-Knighton Medical Center
TERMINATED

Shreveport, Louisiana, 71103, United States
Wright State University & Premier Health
WITHDRAWN

Fairborn, Ohio, 45324, United States

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