Simple skin test may spot Parkinson's risk years early

NCT ID NCT07428447

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a skin biopsy can detect abnormal proteins linked to Parkinson's disease in people with essential tremor, a common movement disorder. Researchers will follow 300 participants aged 50-85 for two years to see who develops Parkinson's. The goal is to find a simple, less invasive way to identify those at highest risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Syn-One Test (skin biopsy for phosphorylated alpha-synuclein)

What this could lead to

If successful, this could lead to a simple skin test that identifies which people with essential tremor are at high risk of developing Parkinson's disease, enabling earlier monitoring or intervention.

What could go wrong

This is an observational study, not a treatment trial. The test may not accurately predict progression, and results may not apply to all patients. It is still early, with only 300 participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

essential tremor movement disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CND Clinical Research Center

    RECRUITING

    Scottsdale, Arizona, 85258, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••