Brain zap study reveals secrets of speech learning
NCT ID NCT07455760
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how two brain areas—the subthalamic nucleus and the ventral intermediate nucleus of the thalamus—help us learn and produce speech. Researchers will temporarily turn deep brain stimulation (DBS) on or off in 80 people with Parkinson's disease or essential tremor while they practice saying new sound sequences. The goal is to understand how DBS affects speech learning, which may lead to better DBS settings that improve both movement and speech.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deep brain stimulation (DBS) targeting the subthalamic nucleus or ventral intermediate nucleus of the thalamus
What this could lead to
If successful, this research could guide doctors in fine-tuning DBS settings to better preserve or improve speech in people with Parkinson's disease or essential tremor.
What could go wrong
This is an early-stage observational study with only 80 participants, so results may not apply to everyone. The temporary turning off of DBS may cause discomfort or temporary worsening of symptoms.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Boston University
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact