Brain pacemaker targets cerebellum to quiet severe tremors
NCT ID NCT07049003
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This study tests whether electrical stimulation of a part of the brain called the deep cerebellar nuclei can safely reduce severe tremor. The participants are adults with essential tremor, cerebellar outflow tremor, or MS-related tremor that has not improved with medication or prior treatments like thalamic deep brain stimulation. The goal is to assess safety and measure changes in tremor severity using a standard rating scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deep Brain Stimulation (Medtronic Percept DBS System)
- What this could lead to
- If successful, this could offer a new treatment option for people with severe tremor who have not benefited from existing therapies.
- What could go wrong
- This is an early-phase safety study with only 12 participants. The approach may not work for everyone, and there are risks associated with brain surgery and device implantation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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