New brain stimulation approach aims to quiet tremors with less power

NCT ID NCT05897775

Recruiting now Symptom relief Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new way to deliver deep brain stimulation (DBS) for essential tremor, called coordinated reset DBS. Instead of constant high-frequency pulses, it uses lower-current patterns that may work better and have fewer downsides. About 23 adults with essential tremor who already have a DBS implant will try both the new and standard stimulation for one week each, and researchers will compare how well each controls tremor and affects daily activities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation device
What this could lead to: If successful, this could offer a more effective and less intense way to control essential tremor, potentially reducing side effects from traditional DBS.
What could go wrong: This is a very small, early-phase study with only 23 participants and short-term follow-up. The new stimulation pattern may not work better than standard DBS, and individual results may vary.

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Conditions

The condition(s) this trial relates to.

essential tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESSENTIAL TREMOR UPPER EXTREMITY ESSENTIAL TREMOR

Contacts and locations

Locations

University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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