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Can a second brain zap tame tremors on both sides?

NCT ID NCT06974916

Recruiting now Disease control Sponsor: InSightec Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This study tests whether a second focused ultrasound treatment on the opposite side of the brain can further reduce tremors in people with essential tremor who already had one treatment. About 100 participants will be randomly assigned to get the second procedure or continue standard care. The main goal is to see if tremor scores improve more in the treated group after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
focused ultrasound (Exablate) procedure
What this could lead to
If successful, this could offer a way to treat tremors on both sides of the body with a non-invasive procedure, potentially reducing the need for medication.
What could go wrong
This is a relatively small, early-stage study (100 people) and focused ultrasound can cause side effects like numbness or balance issues. It is not a cure, and long-term benefits are unproven.

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Conditions

The condition(s) this trial relates to.

essential tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESSENTIAL TREMOR

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Ascires Hospital_ECG Salud

    ACTIVE_NOT_RECRUITING

    Valencia, 46014, Spain

  • Central Japan International Medical Center

    NOT_YET_RECRUITING

    Minokamo, Gifu, Japan

  • Chang Bing Show Chwan Memorial Hospital

    RECRUITING

    Changhua, 500, Taiwan

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, 31008, Spain

  • Fondazione IRCCS Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

  • Germans Trias i Pujol Hospital

    RECRUITING

    Badalona, 08916, Spain

  • HM CINAC- Hospital Universitario HM Puerta del Sur

    RECRUITING

    Móstoles, 28938, Spain

  • Kashiwaba Neurology Hospital

    NOT_YET_RECRUITING

    Sapporo, Hokkaido, Japan

  • Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-Kofukai

    NOT_YET_RECRUITING

    Kita-ku, Osaka, Japan

  • National Taiwan University Hospital

    NOT_YET_RECRUITING

    Taipei, 100225, Taiwan

  • The Walton Center

    NOT_YET_RECRUITING

    Liverpool, L97LJ, United Kingdom

  • Turku University Hospital

    RECRUITING

    Turku, FI20520, Finland

  • Universitätsklinikum Schleswig-Holstein, Campus Kiel (UKSH)

    RECRUITING

    Kiel, 24105, Germany

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