Insightec

This study tests whether a focused ultrasound device can safely open the blood-brain barrier in people with non-small cell lung cancer that has spread to the brain. About 30 participants will receive standard immunotherapy plus the ultrasound procedure. The goal is to see if this…

This study tests whether a second focused ultrasound treatment on the opposite side of the brain can further reduce tremors in people with essential tremor who already had one treatment. About 100 participants will be randomly assigned to get the second procedure or continue stan…

This study is testing a device called ExAblate 4000 that uses focused ultrasound waves to treat non-cancerous brain tumors in children and young adults. The goal is to see if the treatment is safe and can shrink tumors without open surgery. About 20 participants will be enrolled,…

This early-stage trial is testing whether low-intensity focused ultrasound (LIFU) can safely help people with opioid or other substance use disorders. The device sends sound waves to specific brain areas to calm cravings. 29 adults in outpatient treatment will receive both real a…

This registry follows 50 people with tremor-dominant Parkinson's disease who have undergone a focused ultrasound thalamotomy. The procedure uses sound waves to target a small area in the brain that causes tremors. The goal is to collect long-term safety data and measure how well …

This study tracks people with advanced Parkinson's disease who receive a treatment called Exablate, which uses focused ultrasound to target a small area in the brain. The goal is to see how well it reduces medication-resistant motor problems like shaking and stiffness. Researcher…

This early-phase trial tests whether a focused ultrasound device can safely open the blood-brain barrier to deliver a missing enzyme (GCase) directly into the brains of 14 people with Parkinson's disease. The goal is to see if this delivery method is safe and feasible, not yet to…

This study tests a device that uses focused ultrasound to temporarily open the blood-brain barrier in people with Alzheimer's disease. The goal is to see if this is safe and could help treatments reach the brain better. Fifty participants aged 50 to 85 with probable Alzheimer's w…